MeSH term | MeSH ID | Detail |
---|---|---|
Vitamin B 6 Deficiency | D026681 | 10 associated lipids |
Monckeberg Medial Calcific Sclerosis | D050380 | 1 associated lipids |
Osteophyte | D054850 | 2 associated lipids |
Osteoarthritis, Spine | D055013 | 2 associated lipids |
Iodoacetic acid is a lipid of Fatty Acyls (FA) class. Iodoacetic acid is associated with abnormalities such as Photoreceptor degeneration and Post MI. The involved functions are known as Hypoxia, Glycolysis, Metabolic Inhibition, Oxidation and PTPS activity. Iodoacetic acid often locates in Extracellular, Muscle, Mitochondria, Cytoplasmic matrix and Tissue membrane. The associated genes with Iodoacetic acid are SLC33A1 gene, GTF2I gene, Mutant Proteins, TRIM33 gene and oxytocin, 1-desamino-(O-Et-Tyr)(2)-.
To understand associated biological information of Iodoacetic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Iodoacetic acid is suspected in Photoreceptor degeneration, Post MI and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Iodoacetic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Thote T et al. | Localized 3D analysis of cartilage composition and morphology in small animal models of joint degeneration. | 2013 | Osteoarthr. Cartil. | pmid:23747340 |
Kelly S et al. | Spinal nociceptive reflexes are sensitized in the monosodium iodoacetate model of osteoarthritis pain in the rat. | 2013 | Osteoarthr. Cartil. | pmid:23973147 |
Mapp PI et al. | Differences in structural and pain phenotypes in the sodium monoiodoacetate and meniscal transection models of osteoarthritis. | 2013 | Osteoarthr. Cartil. | pmid:23973148 |
Lee J et al. | Coenzyme Q10 ameliorates pain and cartilage degradation in a rat model of osteoarthritis by regulating nitric oxide and inflammatory cytokines. | 2013 | PLoS ONE | pmid:23894457 |
Wang XD et al. | Estrogen aggravates iodoacetate-induced temporomandibular joint osteoarthritis. | 2013 | J. Dent. Res. | pmid:23934157 |
Shao H et al. | Intra-articular injection of xanthan gum reduces pain and cartilage damage in a rat osteoarthritis model. | 2013 | Carbohydr Polym | pmid:23399228 |
Cialdai C et al. | Comparison between oral and intra-articular antinociceptive effect of dexketoprofen and tramadol combination in monosodium iodoacetate-induced osteoarthritis in rats. | 2013 | Eur. J. Pharmacol. | pmid:23891968 |
Escobar-Hoyos LF et al. | Genotoxic and clastogenic effects of monohaloacetic acid drinking water disinfection by-products in primary human lymphocytes. | 2013 | Water Res. | pmid:23602619 |
Dhaneshwar S and Patil D | Chondromodulating chimeric prodrugs of diacetylrhein: synthesis and evaluation in monoiodoacetate-induced hyperalgesia. | 2013 | Med Chem | pmid:22920092 |
Fiaschi T et al. | Redox Regulation of Nonmuscle Myosin Heavy Chain during Integrin Engagement. | 2012 | J Signal Transduct | pmid:22220276 |