MeSH term | MeSH ID | Detail |
---|---|---|
Vitamin B 6 Deficiency | D026681 | 10 associated lipids |
Monckeberg Medial Calcific Sclerosis | D050380 | 1 associated lipids |
Osteophyte | D054850 | 2 associated lipids |
Osteoarthritis, Spine | D055013 | 2 associated lipids |
Iodoacetic acid is a lipid of Fatty Acyls (FA) class. Iodoacetic acid is associated with abnormalities such as Photoreceptor degeneration and Post MI. The involved functions are known as Hypoxia, Glycolysis, Metabolic Inhibition, Oxidation and PTPS activity. Iodoacetic acid often locates in Extracellular, Muscle, Mitochondria, Cytoplasmic matrix and Tissue membrane. The associated genes with Iodoacetic acid are SLC33A1 gene, GTF2I gene, Mutant Proteins, TRIM33 gene and oxytocin, 1-desamino-(O-Et-Tyr)(2)-.
To understand associated biological information of Iodoacetic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Iodoacetic acid is suspected in Photoreceptor degeneration, Post MI and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Iodoacetic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Lai SL et al. | Interprotein disulfide bonds formed during isolation process tighten the structure of the postsynaptic density. | 1999 | J. Neurochem. | pmid:10537073 |
Guo Z et al. | Iodoacetate protects hippocampal neurons against excitotoxic and oxidative injury: involvement of heat-shock proteins and Bcl-2. | 2001 | J. Neurochem. | pmid:11677264 |
Gibson A and Brammer MJ | Incorporation of [14C]glucose into lipids of bovine oligodendroglia. | 1984 | J. Neurochem. | pmid:6747626 |
Thampy KG and Barnes EM | Adenosine transport by primary cultures of neurons from chick embryo brain. | 1983 | J. Neurochem. | pmid:6827282 |
Cervia D et al. | Modulation of the neuronal response to ischaemia by somatostatin analogues in wild-type and knock-out mouse retinas. | 2008 | J. Neurochem. | pmid:18624922 |
Dóra E | Glycolysis and epilepsy-induced changes in cerebrocortical NAD/NADH redox state. | 1983 | J. Neurochem. | pmid:6644311 |
Wurm A et al. | Glial cell-derived glutamate mediates autocrine cell volume regulation in the retina: activation by VEGF. | 2008 | J. Neurochem. | pmid:17953668 |
Gysin R and Flanagan SD | Alkylation of free sulfhydryls fortifies electroplax subsynaptic structures. | 1987 | J. Neurochem. | pmid:3110373 |
Wood JP et al. | Energy substrate requirements for survival of rat retinal cells in culture: the importance of glucose and monocarboxylates. | 2005 | J. Neurochem. | pmid:15836627 |
Sabri MI and Ochs S | Inhibition of glyceraldehyde-3-phosphate dehydrogenase in mammalian nerve by iodoacetic acid. | 1971 | J. Neurochem. | pmid:4398402 |
Ochs S and Smith CB | Fast axoplasmic transport in mammalian nerve in vitro after block of glycolysis with iodoacetic acid. | 1971 | J. Neurochem. | pmid:4105449 |
Di-Capua N et al. | Protein kinase C-epsilon is involved in the adenosine-activated signal transduction pathway conferring protection against ischemia-reperfusion injury in primary rat neuronal cultures. | 2003 | J. Neurochem. | pmid:12559003 |
Spector R and Goldberg MJ | Active transport of nicotine by the isolated choroid plexus in vitro. | 1982 | J. Neurochem. | pmid:7108560 |
Ientile R et al. | Polyamine localization and biosynthesis in chemically fractionated rat retina. | 1986 | J. Neurochem. | pmid:3760865 |
Parkinson FE and Xiong W | Stimulus- and cell-type-specific release of purines in cultured rat forebrain astrocytes and neurons. | 2004 | J. Neurochem. | pmid:15009686 |
Rego AC et al. | Adenosine triphosphate degradation products after oxidative stress and metabolic dysfunction in cultured retinal cells. | 1997 | J. Neurochem. | pmid:9282947 |
Otero de Bengtsson MS et al. | Involvement of a disulfide bond in the binding of flunitrazepam to the benzodiazepine receptor from bovine cerebral cortex. | 1993 | J. Neurochem. | pmid:8380435 |
Uto A et al. | Delayed neuronal death after brief histotoxic hypoxia in vitro. | 1995 | J. Neurochem. | pmid:7722504 |
Pyza E and Górska-Andrzejak J | Involvement of glial cells in rhythmic size changes in neurons of the housefly's visual system. | 2004 | J. Neurobiol. | pmid:15085538 |
Reidarson TH et al. | Inducible macrophage cytotoxins. I. Biokinetics of activation and release in vitro. | 1982 | J. Natl. Cancer Inst. | pmid:6956764 |
Rheins MS and Filppi JA | Iodoacetate-induced inhibition and enhancement of spontaneous leukemia in AKR mice. | 1977 | J. Natl. Cancer Inst. | pmid:857029 |
Ferrero ME et al. | Inhibition of glycolysis and interference with protein synthesis in hepatoma cells. | 1977 | J. Natl. Cancer Inst. | pmid:190411 |
Varriano-Marston E et al. | The structure and disposition of crossbridges in deep-etched fish muscle. | 1984 | J. Muscle Res. Cell. Motil. | pmid:6541228 |
Kasuga N and Umazume Y | Deterioration induced by physiological concentration of calcium ions in skinned muscle fibres. | 1990 | J. Muscle Res. Cell. Motil. | pmid:2351746 |
Gilbert SH and Ford LE | The thermoelastic effect in rigor muscle of the frog. | 1986 | J. Muscle Res. Cell. Motil. | pmid:3485655 |
Sigalov E et al. | VIP-Related protection against lodoacetate toxicity in pheochromocytoma (PC12) cells: a model for ischemic/hypoxic injury. | 2000 | J. Mol. Neurosci. | pmid:11303779 |
Shani V et al. | Involvement of Src tyrosine kinases (SFKs) and of focal adhesion kinase (FAK) in the injurious mechanism in rat primary neuronal cultures exposed to chemical ischemia. | 2009 | J. Mol. Neurosci. | pmid:18584337 |
Gillespie JM et al. | A comparison of lizard claw keratin proteins with those of avian beak and claw. | 1982 | J. Mol. Evol. | pmid:6178835 |
Chung TH et al. | 17beta-estradiol reduces the effect of metabolic inhibition on gap junction intercellular communication in rat cardiomyocytes via the estrogen receptor. | 2004 | J. Mol. Cell. Cardiol. | pmid:15522278 |
Barrigon S et al. | Characterization of the calcium overload in cultured neonatal rat cardiomyocytes under metabolic inhibition. | 1996 | J. Mol. Cell. Cardiol. | pmid:8782074 |
Jennings RB et al. | Total ischemia III: Effect of inhibition of anaerobic glycolysis. | 1989 | J. Mol. Cell. Cardiol. | pmid:2733029 |
Rodrigo GC et al. | Dinitrophenol pretreatment of rat ventricular myocytes protects against damage by metabolic inhibition and reperfusion. | 2002 | J. Mol. Cell. Cardiol. | pmid:12056859 |
Zoref-Shani E et al. | Pathways of adenine nucleotide catabolism in primary rat cardiomyocyte cultures. | 1988 | J. Mol. Cell. Cardiol. | pmid:3259263 |
Dumont M and Lemaire S | Interactions of dynorphin A-(1-13) and nociceptin with cardiac D2 binding sites: inhibition of ischemia-evoked release of noradrenaline from synaptosomal-mitochondrial fractions. | 2000 | J. Mol. Cell. Cardiol. | pmid:10900181 |
Bukoski RD and Sparks HV | Adenosine production and release by adult rat cardiocytes. | 1986 | J. Mol. Cell. Cardiol. | pmid:3016289 |
Carlsson L | A crucial role of ongoing anaerobic glycolysis in attenuating acute ischemia-induced release of myocardial noradrenaline. | 1988 | J. Mol. Cell. Cardiol. | pmid:3398056 |
MejÃa-Alvarez R and Marban E | Mechanism of the increase in intracellular sodium during metabolic inhibition: direct evidence against mediation by voltage-dependent sodium channels. | 1992 | J. Mol. Cell. Cardiol. | pmid:1336064 |
Cappelli-Bigazzi M et al. | Role of oxidative metabolism on endothelium-dependent vascular relaxation of isolated vessels. | 1997 | J. Mol. Cell. Cardiol. | pmid:9152848 |
Higgins TJ et al. | The relationship between glycolysis, fatty acid metabolism and membrane integrity in neonatal myocytes. | 1981 | J. Mol. Cell. Cardiol. | pmid:7277506 |
Senges J et al. | Effect of glycolytic inhibitors on the sinoatrial node, atrium and atrioventricular node in the rabbit heart. | 1981 | J. Mol. Cell. Cardiol. | pmid:7299831 |
Im JH et al. | Energy dependent insulin binding, internalization and degradation in isolated cardiac myocytes from normal and diabetic rats. | 1986 | J. Mol. Cell. Cardiol. | pmid:3514924 |
Schumacher CA et al. | Energy-dependent transport of calcium to the extracellular space during acute ischemia of the rat heart. | 1998 | J. Mol. Cell. Cardiol. | pmid:9737948 |
Coombs PJ et al. | Identification of novel contributions to high-affinity glycoprotein-receptor interactions using engineered ligands. | 2010 | J. Mol. Biol. | pmid:20004209 |
Creighton TE and Goldenberg DP | Kinetic role of a meta-stable native-like two-disulphide species in the folding transition of bovine pancreatic trypsin inhibitor. | 1984 | J. Mol. Biol. | pmid:6210370 |
Monika EM et al. | A thioreduction pathway tethered to the membrane for periplasmic cytochromes c biogenesis; in vitro and in vivo studies. | 1997 | J. Mol. Biol. | pmid:9299319 |
Knauf PA et al. | Calcium-potassium-stimulated net potassium efflux from human erythrocyte ghosts. | 1975 | J. Membr. Biol. | pmid:2781 |
Masters BR and Fanestil DD | Metabolic dependence of the offset of antidiuretic hormone-induced osmotic flow of water across the toad urinary bladder. | 1979 | J. Membr. Biol. | pmid:490626 |
Flagg-Newton J and Loewenstein WR | Experimental depression of junctional membrane permeability in mammalian cell culture. A study with tracer molecules in the 300 to 800 Dalton range. | 1979 | J. Membr. Biol. | pmid:41101 |
Alvarez J et al. | All or none cell responses of Ca2+-dependent K channels elicited by calcium or lead in human red cells can be explained by heterogeneity of agonist distribution. | 1988 | J. Membr. Biol. | pmid:3193453 |
Spoerl E et al. | Reversible permeability changes in the membrane of a yeast cell sugar compartment. | 1975 | J. Membr. Biol. | pmid:1095751 |
Gomme J | D-Glucose transport across the apical membrane of the surface epithelium in Nereis diversicolor. | 1981 | J. Membr. Biol. | pmid:6792359 |
Lees-Miller JP and Caveney S | Drugs that block calmoduLin activity inhibit cell-to-cell coupling in the epidermis of Tenebrio molitor. | 1982 | J. Membr. Biol. | pmid:6128425 |
Kutchai H | Uptake of sorbitol by chick embryo heart cells at various stages of development. | 1975 | J. Membr. Biol. | pmid:1214274 |
Neurath AR and Strick N | Antibodies as immunological probes for studying the denaturation of HBsAg. | 1981 | J. Med. Virol. | pmid:6165803 |
Hynes WL and Tagg JR | Proteinase-related broad-spectrum inhibitory activity among group-A streptococci. | 1986 | J. Med. Microbiol. | pmid:3534275 |
Barrow PA and Lovell MA | Invasion of Vero cells by Salmonella species. | 1989 | J. Med. Microbiol. | pmid:2643706 |
Gopal-Srivastava R and Hylemon PB | Purification and characterization of bile salt hydrolase from Clostridium perfringens. | 1988 | J. Lipid Res. | pmid:2903208 |
Uyama T et al. | The tumor suppressor gene H-Rev107 functions as a novel Ca2+-independent cytosolic phospholipase A1/2 of the thiol hydrolase type. | 2009 | J. Lipid Res. | pmid:19047760 |
Bennett TA et al. | Evidence for a third component in neutrophil aggregation: potential roles of O-linked glycoproteins as L-selectin counter-structures. | 1995 | J. Leukoc. Biol. | pmid:7595051 |
Lowenhaupt RW et al. | Factors which influence blood platelet migration. | 1977 | J. Lab. Clin. Med. | pmid:17642 |
Said HM et al. | Intestinal surface acid microclimate in vitro and in vivo in the rat. | 1986 | J. Lab. Clin. Med. | pmid:3701189 |
Mengelers HJ et al. | Cognate interaction between human lymphocytes and eosinophils is mediated by beta 2-integrins and very late antigen-4. | 1995 | J. Lab. Clin. Med. | pmid:7545203 |
Rosenberg EM et al. | Phosphate accumulation by the isolated renal tubule and the effects of parathyroid hormone and cyclic adenosine monophosphate. | 1980 | J. Lab. Clin. Med. | pmid:6248607 |
Malinconico SM et al. | Hementin: anticoagulant protease from the salivary gland of the leech Haementeria ghilianii. | 1984 | J. Lab. Clin. Med. | pmid:6361187 |
Choi SJ et al. | Effect of ketamine on apoptosis by energy deprivation in astroglioma cells using flow cytometry system. | 2005 | J. Korean Med. Sci. | pmid:15716615 |
Six S et al. | Reactivity of the N-terminal cysteine residues in active and inactive forms of FNR, and O2-responsive, Fe containing transcriptional regulator of Escherichia coli. | 1996 | J. Inorg. Biochem. | pmid:8729797 |
Bongers J et al. | Platinum(II) binding to metallothioneins. | 1988 | J. Inorg. Biochem. | pmid:3216202 |
Lai CY et al. | Chemistry of cholera toxin: the subunit structure. | 1976 | J. Infect. Dis. | pmid:815448 |
Chersi A et al. | 14C-labeling of synthetic peptides. | 1988 | J. Immunol. Methods | pmid:3379315 |
Rector ES et al. | A method for the preparation of protein-protein conjugates of predetermined composition. | 1978 | J. Immunol. Methods | pmid:102705 |
Houen G and Jensen OM | Conjugation to preactivated proteins using divinylsulfone and iodoacetic acid. | 1995 | J. Immunol. Methods | pmid:7745248 |
Saito T and Yamaguchi J | 2-Chloroadenosine: a selective lethal effect to mouse macrophages and its mechanism. | 1985 | J. Immunol. | pmid:3968433 |
Walker WS and Demus A | Antibody-dependent cytolysis of chicken erythrocytes by an in vitro-established line of mouse peritoneal macrophages. | 1975 | J. Immunol. | pmid:1167563 |
Trinchieri G and De Marchi M | Antibody-dependent cell-mediated cytotoxicity in humans. II. Energy requirement. | 1975 | J. Immunol. | pmid:1151059 |
Yasaka T et al. | Monocyte aggregation and superoxide anion release in response to formyl-methionyl-leucyl-phenylalanine (FMLP) and platelet-activating factor (PAF). | 1982 | J. Immunol. | pmid:6278021 |
O'Flaherty JT et al. | Influence of inhibitors of cellular function on chemotactic factor-induced neutrophil aggregation. | 1977 | J. Immunol. | pmid:915280 |
Leif RC et al. | A procedure for dissociating Ayre scrape samples. | 1977 | J. Histochem. Cytochem. | pmid:894001 |
Jasra N et al. | Characterization of glucose uptake by Trichuris globulosa (Nematoda) in vitro. | 1990 | J. Helminthol. | pmid:2230035 |
Xu M and Akabas MH | Identification of channel-lining residues in the M2 membrane-spanning segment of the GABA(A) receptor alpha1 subunit. | 1996 | J. Gen. Physiol. | pmid:8833341 |
Herness MS | Neurophysiological and biophysical evidence on the mechanism of electric taste. | 1985 | J. Gen. Physiol. | pmid:2993476 |
PRICE WH | Bacteriophage formation without bacterial growth; the effect of iodoacetate, fluoride, gramicidin, and azide on the formation of bacteriophage. | 1947 | J. Gen. Physiol. | pmid:18896936 |
Busturia A and Lagunas R | Catabolite inactivation of the glucose transport system in Saccharomyces cerevisiae. | 1986 | J. Gen. Microbiol. | pmid:3519857 |
Stewart LM et al. | Energy coupling to K+ uptake via the Trk system in Escherichia coli: the role of ATP. | 1985 | J. Gen. Microbiol. | pmid:3886836 |
Ozaki K and Ito S | Purification and properties of an acid endo-1,4-beta-glucanase from Bacillus sp. KSM-330. | 1991 | J. Gen. Microbiol. | pmid:2045781 |
White BA and Clewell DB | Identification and partial purification of a dipeptidyl aminopeptidase from Streptococcus faecalis. | 1986 | J. Gen. Microbiol. | pmid:3095489 |
Thomas AM et al. | The uptake of choline by Streptococcus pneumoniae. | 1978 | J. Gen. Microbiol. | pmid:34010 |
Piper B et al. | The influence of various substances on the gliding motility of Mycoplasma mobile 163K. | 1987 | J. Gen. Microbiol. | pmid:3446749 |
Horisaki T et al. | Isolation and characterization of monochloroacetic acid-degrading bacteria. | 2011 | J. Gen. Appl. Microbiol. | pmid:22139456 |
Gong K et al. | Rat model of lumbar facet joint osteoarthritis associated with facet-mediated mechanical hyperalgesia induced by intra-articular injection of monosodium iodoacetate. | 2011 | J. Formos. Med. Assoc. | pmid:21497277 |
Stone BB and Sidell BD | Metabolic responses of striped bass (Morone saxatilis) to temperature acclimation. I. Alterations in carbon sources for hepatic energy metabolism. | 1981 | J. Exp. Zool. | pmid:7338722 |
Lane HC | Nucleoside triphosphate changes during the peripheral life-span of erythrocytes of adult rainbow trout (Salmo gairdneri). | 1984 | J. Exp. Zool. | pmid:6470650 |
Bailey JR et al. | Maintenance of resting tension in the american eel (Anguilla rostrata L.) heart is dependent upon exogenous fuel and the sarcoplasmic reticulum. | 2000 | J. Exp. Zool. | pmid:10797323 |
Li M et al. | A novel function for vimentin: the potential biomarker for predicting melanoma hematogenous metastasis. | 2010 | J. Exp. Clin. Cancer Res. | pmid:20701774 |
Izumi M et al. | RBCS1A and RBCS3B, two major members within the Arabidopsis RBCS multigene family, function to yield sufficient Rubisco content for leaf photosynthetic capacity. | 2012 | J. Exp. Bot. | pmid:22223809 |
Kaloyianni M et al. | Effect of adenosine on glucose metabolism of Rana ridibunda erythrocytes. | 1993 | J. Exp. Biol. | pmid:8487000 |
Espelt MV et al. | Volumetric and ionic responses of goldfish hepatocytes to anisotonic exposure and energetic limitation. | 2003 | J. Exp. Biol. | pmid:12502772 |
Farrar RS et al. | Steroid-induced cardiac contractility requires exogenous glucose, glycolysis and the sarcoplasmic reticulum in rainbow trout. | 2006 | J. Exp. Biol. | pmid:16709913 |
Winmill RE et al. | Development of the respiratory response to hypoxia in the isolated brainstem of the bullfrog Rana catesbeiana. | 2005 | J. Exp. Biol. | pmid:15634841 |
Riegel JA | Factors affecting glomerular function in the pacific hagfish Eptatretus stouti (Lockington). | 1978 | J. Exp. Biol. | pmid:650147 |
Baum KF et al. | Purine nucleoside and nucleobase cell membrane transport in Giardia lamblia. | 1993 Sep-Oct | J. Eukaryot. Microbiol. | pmid:8401476 |