Iodoacetic acid

Iodoacetic acid is a lipid of Fatty Acyls (FA) class. Iodoacetic acid is associated with abnormalities such as Photoreceptor degeneration and Post MI. The involved functions are known as Hypoxia, Glycolysis, Metabolic Inhibition, Oxidation and PTPS activity. Iodoacetic acid often locates in Extracellular, Muscle, Mitochondria, Cytoplasmic matrix and Tissue membrane. The associated genes with Iodoacetic acid are SLC33A1 gene, GTF2I gene, Mutant Proteins, TRIM33 gene and oxytocin, 1-desamino-(O-Et-Tyr)(2)-.

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Introduction

To understand associated biological information of Iodoacetic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Iodoacetic acid?

Iodoacetic acid is suspected in Photoreceptor degeneration, Post MI and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Iodoacetic acid

MeSH term MeSH ID Detail
Vitamin B 6 Deficiency D026681 10 associated lipids
Monckeberg Medial Calcific Sclerosis D050380 1 associated lipids
Osteophyte D054850 2 associated lipids
Osteoarthritis, Spine D055013 2 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Iodoacetic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Iodoacetic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Iodoacetic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Iodoacetic acid?

There are no associated biomedical information in the current reference collection.

What genes are associated with Iodoacetic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Iodoacetic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Iodoacetic acid

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Authors Title Published Journal PubMed Link
Orita S et al. Pain-related sensory innervation in monoiodoacetate-induced osteoarthritis in rat knees that gradually develops neuronal injury in addition to inflammatory pain. 2011 BMC Musculoskelet Disord pmid:21679434
Nam J et al. Transcriptome-wide gene regulation by gentle treadmill walking during the progression of monoiodoacetate-induced arthritis. 2011 Arthritis Rheum. pmid:21400474
Siebelt M et al. Quantifying osteoarthritic cartilage changes accurately using in vivo microCT arthrography in three etiologically distinct rat models. 2011 J. Orthop. Res. pmid:21520262
Huang J et al. Isolation, characterization and identification of a Paracoccus sp. 2-haloacid-degrading bacterium from the marine sponge Hymeniacidon perlevis. 2011 J. Basic Microbiol. pmid:21298680
Schuelert N et al. Local application of the endocannabinoid hydrolysis inhibitor URB597 reduces nociception in spontaneous and chemically induced models of osteoarthritis. 2011 Pain pmid:21185649
Wang W et al. Selective rod degeneration and partial cone inactivation characterize an iodoacetic acid model of Swine retinal degeneration. 2011 Invest. Ophthalmol. Vis. Sci. pmid:21896868
Nam J et al. Sequential alterations in catabolic and anabolic gene expression parallel pathological changes during progression of monoiodoacetate-induced arthritis. 2011 PLoS ONE pmid:21931681
Buchwalow I et al. Non-specific binding of antibodies in immunohistochemistry: fallacies and facts. 2011 Sci Rep pmid:22355547
Bezawada J et al. Recovery of Bacillus licheniformis Alkaline Protease from Supernatant of Fermented Wastewater Sludge Using Ultrafiltration and Its Characterization. 2011 Biotechnol Res Int pmid:21876816
Cherel P et al. Joint analysis of quantitative trait loci and major-effect causative mutations affecting meat quality and carcass composition traits in pigs. 2011 BMC Genet. pmid:21875434
Rawlings ND et al. Asparagine peptide lyases: a seventh catalytic type of proteolytic enzymes. 2011 J. Biol. Chem. pmid:21832066
House SA et al. Giardia flagellar motility is not directly required to maintain attachment to surfaces. 2011 PLoS Pathog. pmid:21829364
Yu J et al. Mussel protein adhesion depends on interprotein thiol-mediated redox modulation. 2011 Nat. Chem. Biol. pmid:21804534
Li A et al. Serotonin Receptor 2A/C Is Involved in Electroacupuncture Inhibition of Pain in an Osteoarthritis Rat Model. 2011 Evid Based Complement Alternat Med pmid:21799685
Liao HH et al. Down-regulation of granulocyte-macrophage colony-stimulating factor by 3C-like proteinase in transfected A549 human lung carcinoma cells. 2011 BMC Immunol. pmid:21324206
Porteus C et al. Time domains of the hypoxic ventilatory response in ectothermic vertebrates. 2011 J. Comp. Physiol. B, Biochem. Syst. Environ. Physiol. pmid:21312038
Sánchez-Aragó M and Cuezva JM The bioenergetic signature of isogenic colon cancer cells predicts the cell death response to treatment with 3-bromopyruvate, iodoacetate or 5-fluorouracil. 2011 J Transl Med pmid:21303518
Singla DK et al. TGF-β2 treatment enhances cytoprotective factors released from embryonic stem cells and inhibits apoptosis in infarcted myocardium. 2011 Am. J. Physiol. Heart Circ. Physiol. pmid:21297031
Samgina TY et al. Novel cysteine tags for the sequencing of non-tryptic disulfide peptides of anurans: ESI-MS study of fragmentation efficiency. 2011 J. Am. Soc. Mass Spectrom. pmid:21979873
Al-Jallad HF et al. Plasma membrane factor XIIIA transglutaminase activity regulates osteoblast matrix secretion and deposition by affecting microtubule dynamics. 2011 PLoS ONE pmid:21283799