MeSH term | MeSH ID | Detail |
---|---|---|
Vitamin B 6 Deficiency | D026681 | 10 associated lipids |
Monckeberg Medial Calcific Sclerosis | D050380 | 1 associated lipids |
Osteophyte | D054850 | 2 associated lipids |
Osteoarthritis, Spine | D055013 | 2 associated lipids |
Iodoacetic acid is a lipid of Fatty Acyls (FA) class. Iodoacetic acid is associated with abnormalities such as Photoreceptor degeneration and Post MI. The involved functions are known as Hypoxia, Glycolysis, Metabolic Inhibition, Oxidation and PTPS activity. Iodoacetic acid often locates in Extracellular, Muscle, Mitochondria, Cytoplasmic matrix and Tissue membrane. The associated genes with Iodoacetic acid are SLC33A1 gene, GTF2I gene, Mutant Proteins, TRIM33 gene and oxytocin, 1-desamino-(O-Et-Tyr)(2)-.
To understand associated biological information of Iodoacetic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Iodoacetic acid is suspected in Photoreceptor degeneration, Post MI and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Iodoacetic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Hall AM et al. | Albumin uptake in OK cells exposed to rotenone: a model for studying the effects of mitochondrial dysfunction on endocytosis in the proximal tubule? | 2010 | Nephron Physiol | pmid:20484937 |
Mielicki W and Wierzbicki R | Factor X-activating activity from Guerin epithelioma. | 1988 | Neoplasma | pmid:3405336 |
Akimov IuA and Shuba MF | [The effect of mono-iodoacetic acid on the electrophysiologic properties of the giant neurons of the grape snail]. | 1972 Jan-Feb | Neirofiziologiia | pmid:5073433 |
Baranova IP et al. | [Effect of iodoacetic acid and sodium fluoride on the development of lactic acid bacterium Streptococcus lactis, a producer of the polypeptide antibiotic nisin]. | 1976 | Nauchnye Doki Vyss Shkoly Biol Nauki | pmid:828507 |
Voronova NV and Chumachenko AA | [The effect of limiting neuronal energy metabolism on the level of impulse activity and membrane potentials]. | 1989 | Nauchnye Doki Vyss Shkoly Biol Nauki | pmid:2611296 |
Lemasters JJ et al. | Blebbing, free Ca2+ and mitochondrial membrane potential preceding cell death in hepatocytes. | 1987 Jan 1-7 | Nature | pmid:3099216 |
Santos-Rosa H et al. | Histone H3 tail clipping regulates gene expression. | 2009 | Nat. Struct. Mol. Biol. | pmid:19079264 |
Adachi T et al. | S-Glutathiolation by peroxynitrite activates SERCA during arterial relaxation by nitric oxide. | 2004 | Nat. Med. | pmid:15489859 |
Yu J et al. | Mussel protein adhesion depends on interprotein thiol-mediated redox modulation. | 2011 | Nat. Chem. Biol. | pmid:21804534 |
McCormick SP et al. | Apolipoprotein E variation in patients with hyperlipidaemia: DNA and protein phenotyping. | 1989 | N. Z. Med. J. | pmid:2797589 |
Malcolm GB et al. | Biochemical and serological characteristics of soluble yeast phase antigens of Histoplasma capsulatum. | 1979 | Mycopathologia | pmid:450035 |
Kirsch-Volders M | Differential staining of chromosomes and spindle cannot be used as an assay to determine the effect of cancer promoters on primary cultures of human fibroblasts. | 1986 Aug-Sep | Mutat. Res. | pmid:2427946 |
Bogliolo M et al. | Alternative metabolic pathways for energy supply and resistance to apoptosis in Fanconi anaemia. | 2002 | Mutagenesis | pmid:11752230 |
Liviac D et al. | Genotoxicity testing of three monohaloacetic acids in TK6 cells using the cytokinesis-block micronucleus assay. | 2010 | Mutagenesis | pmid:20547559 |
Kuwabara T et al. | 31P-NMR studies on an animal model of human defective muscle glycolysis. | 1986 | Muscle Nerve | pmid:3951487 |
Heller SL et al. | IMP response: an indicator of metabolic stress in working muscle. | 1986 Jul-Aug | Muscle Nerve | pmid:3736584 |
Lunetta C et al. | Impaired expression of insulin-like growth factor-1 system in skeletal muscle of amyotrophic lateral sclerosis patients. | 2012 | Muscle Nerve | pmid:22246875 |
Cairns SP and Dulhunty AF | Beta-adrenergic potentiation of E-C coupling increases force in rat skeletal muscle. | 1993 | Muscle Nerve | pmid:8232387 |
Ochrietor JD et al. | The 2M6 antigen is a Müller cell-specific intracellular membrane-associated protein of the sarcolemmal-membrane-associated protein family and is also TopAP. | 2010 | Mol. Vis. | pmid:20577597 |
Zhu Y et al. | Differential gene expression in mouse retina related to regional differences in vulnerability to hyperoxia. | 2010 | Mol. Vis. | pmid:20454693 |
Xu S et al. | Transport of L-carnitine in human corneal and conjunctival epithelial cells. | 2010 | Mol. Vis. | pmid:21045919 |
Nochez Y et al. | Acute and late-onset optic atrophy due to a novel OPA1 mutation leading to a mitochondrial coupling defect. | 2009 | Mol. Vis. | pmid:19325939 |
Srivastava OP et al. | Isolation and characterization of betaA3-crystallin associated proteinase from alpha-crystallin fraction of human lenses. | 2008 | Mol. Vis. | pmid:18949065 |
Duan X et al. | Proteomic analysis of aqueous humor from patients with myopia. | 2008 | Mol. Vis. | pmid:18334949 |
Hashimoto S et al. | Low oxygen tension during in vitro maturation is beneficial for supporting the subsequent development of bovine cumulus-oocyte complexes. | 2000 | Mol. Reprod. Dev. | pmid:11066064 |
Horton JK et al. | Paraquat uptake into freshly isolated rabbit lung epithelial cells and its reduction to the paraquat radical under anaerobic conditions. | 1986 | Mol. Pharmacol. | pmid:3010076 |
Yeramian E et al. | N-ethylmaleimide-induced changes in agonist affinity for histamine H1-receptors in the guinea pig brain. | 1985 | Mol. Pharmacol. | pmid:4022000 |
Snyder RM et al. | Effect of auranofin and other gold complexes on the activity of phospholipase C. | 1987 | Mol. Pharmacol. | pmid:3118179 |
Tolonen AC et al. | Targeted gene inactivation in Clostridium phytofermentans shows that cellulose degradation requires the family 9 hydrolase Cphy3367. | 2009 | Mol. Microbiol. | pmid:19775243 |
Elmore MJ et al. | Activation of potassium efflux from Escherichia coli by glutathione metabolites. | 1990 | Mol. Microbiol. | pmid:2192231 |
Trageser M and Unden G | Role of cysteine residues and of metal ions in the regulatory functioning of FNR, the transcriptional regulator of anaerobic respiration in Escherichia coli. | 1989 | Mol. Microbiol. | pmid:2668693 |
Pyle JE and Howe HB | Uptake and dissimilation of glycerol by wild type and glycerol nonutilizing strains of Neurospora crassa. | 1983 | Mol. Gen. Genet. | pmid:6222238 |
Morgan A and Maliga P | Rapid chloroplast segregation and recombination of mitochondrial DNA in Brassica cybrids. | 1987 | Mol. Gen. Genet. | pmid:17191340 |
Verity MA et al. | Paradoxical potentiation by low extracellular Ca2+ of acute chemical anoxic neuronal injury in cerebellar granule cell culture. | 1991 | Mol. Chem. Neuropathol. | pmid:1687239 |
Hazum E | Some characteristics of GnRH receptors in rat-pituitary membranes: differences between an agonist and and antagonist. | 1981 | Mol. Cell. Endocrinol. | pmid:6269924 |
Necessary PC et al. | Activity of alkylated prolactin and human growth hormone in receptor and cell assays. | 1985 | Mol. Cell. Endocrinol. | pmid:2984068 |
Visser TJ et al. | Differential sensitivity of brain iodothyronine 5'-deiodinases to sulfhydryl-blocking reagents. | 1983 | Mol. Cell. Endocrinol. | pmid:6653873 |
Rodesch F et al. | Compartmentalization and movement of calcium in the thyroid. | 1976 Aug-Sep | Mol. Cell. Endocrinol. | pmid:782959 |
Durnam DM and Palmiter RD | Induction of metallothionein-I mRNA in cultured cells by heavy metals and iodoacetate: evidence for gratuitous inducers. | 1984 | Mol. Cell. Biol. | pmid:6717431 |
Plessel G et al. | m3G cap hypermethylation of U1 small nuclear ribonucleoprotein (snRNP) in vitro: evidence that the U1 small nuclear RNA-(guanosine-N2)-methyltransferase is a non-snRNP cytoplasmic protein that requires a binding site on the Sm core domain. | 1994 | Mol. Cell. Biol. | pmid:8196654 |
Helm BA and Gunn JM | The effect of insulinomimetic agents on protein degradation in H35 hepatoma cells. | 1986 | Mol. Cell. Biochem. | pmid:3534545 |
Lee CY et al. | Purification and characterization of mouse glucose 6-phosphate dehydrogenase. | 1979 | Mol. Cell. Biochem. | pmid:460173 |
Marlewski M et al. | Accelerated degradation of adenine nucleotide in erythrocytes of patients with chronic renal failure. | 2000 | Mol. Cell. Biochem. | pmid:11129963 |
Kaye NM and Jollès P | Characterization of the amino acids of bovine fibrinogen involved in the fibrinogen-thrombin interaction of the blood clotting process. Comparison with the milk clotting process. | 1978 | Mol. Cell. Biochem. | pmid:360048 |
Brooks SP and Storey KB | Control of glycolytic enzyme binding: effect of changing enzyme substrate concentrations on in vivo enzyme distributions. | 1993 | Mol. Cell. Biochem. | pmid:8350861 |
Hama T et al. | Purification of dipeptidyl-aminopeptidase IV from human kidney by anti dipeptidyl-aminopeptidase IV affinity chromatography. | 1982 | Mol. Cell. Biochem. | pmid:7043238 |
Zervos C and Adams E | Hydroxyproline-2-epimerase of Pseudomonas: active-site peptides. | 1975 | Mol. Cell. Biochem. | pmid:1165763 |
Grubbs RD and Walter A | Determination of cytosolic Mg2+ activity and buffering in BC3H-1 cells with mag-fura-2. | 1994 | Mol. Cell. Biochem. | pmid:7854327 |
Argaraña CE et al. | Release of [14C]tyrosine from tubulinyl-[14C]tyrosine by brain extract. Separation of a carboxypeptidase from tubulin-tyrosine ligase. | 1978 | Mol. Cell. Biochem. | pmid:25379 |
Hacker TA et al. | The role of glucose metabolism in a pig heart model of short-term hibernation. | 1998 | Mol. Cell. Biochem. | pmid:9546633 |