Iodoacetic acid

Iodoacetic acid is a lipid of Fatty Acyls (FA) class. Iodoacetic acid is associated with abnormalities such as Photoreceptor degeneration and Post MI. The involved functions are known as Hypoxia, Glycolysis, Metabolic Inhibition, Oxidation and PTPS activity. Iodoacetic acid often locates in Extracellular, Muscle, Mitochondria, Cytoplasmic matrix and Tissue membrane. The associated genes with Iodoacetic acid are SLC33A1 gene, GTF2I gene, Mutant Proteins, TRIM33 gene and oxytocin, 1-desamino-(O-Et-Tyr)(2)-.

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Introduction

To understand associated biological information of Iodoacetic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Iodoacetic acid?

Iodoacetic acid is suspected in Photoreceptor degeneration, Post MI and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Iodoacetic acid

MeSH term MeSH ID Detail
Vitamin B 6 Deficiency D026681 10 associated lipids
Monckeberg Medial Calcific Sclerosis D050380 1 associated lipids
Osteophyte D054850 2 associated lipids
Osteoarthritis, Spine D055013 2 associated lipids
Per page 10 20 50 100 | Total 54

PubChem Associated disorders and diseases

What pathways are associated with Iodoacetic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Iodoacetic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Iodoacetic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Iodoacetic acid?

There are no associated biomedical information in the current reference collection.

What genes are associated with Iodoacetic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Iodoacetic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Iodoacetic acid

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Authors Title Published Journal PubMed Link
Lee J et al. Coenzyme Q10 ameliorates pain and cartilage degradation in a rat model of osteoarthritis by regulating nitric oxide and inflammatory cytokines. 2013 PLoS ONE pmid:23894457
Calmettes G et al. Improved energy supply regulation in chronic hypoxic mouse counteracts hypoxia-induced altered cardiac energetics. 2010 PLoS ONE pmid:20174637
Edes K et al. JS-K, a nitric oxide prodrug, has enhanced cytotoxicity in colon cancer cells with knockdown of thioredoxin reductase 1. 2010 PLoS ONE pmid:20098717
Ahamed J et al. In vitro and in vivo evidence that thrombospondin-1 (TSP-1) contributes to stirring- and shear-dependent activation of platelet-derived TGF-beta1. 2009 PLoS ONE pmid:19672301
Cao S et al. A mitochondria-dependent pathway mediates the apoptosis of GSE-induced yeast. 2012 PLoS ONE pmid:22403727
Fagerholm S et al. Rapid insulin-dependent endocytosis of the insulin receptor by caveolae in primary adipocytes. 2009 PLoS ONE pmid:19543529
Wei Y et al. Binding to the minor groove of the double-strand, tau protein prevents DNA from damage by peroxidation. 2008 PLoS ONE pmid:18596978
Goytia M et al. Molecular and structural discrimination of proline racemase and hydroxyproline-2-epimerase from nosocomial and bacterial pathogens. 2007 PLoS ONE pmid:17849014
Du J et al. The protein partners of GTP cyclohydrolase I in rat organs. 2012 PLoS ONE pmid:22479495
Thakur M et al. Characterisation of a peripheral neuropathic component of the rat monoiodoacetate model of osteoarthritis. 2012 PLoS ONE pmid:22470467
Sun L et al. N-acetylcysteine protects against apoptosis through modulation of group I metabotropic glutamate receptor activity. 2012 PLoS ONE pmid:22442667
Nam J et al. Sequential alterations in catabolic and anabolic gene expression parallel pathological changes during progression of monoiodoacetate-induced arthritis. 2011 PLoS ONE pmid:21931681
Menkhorst EM et al. Decidual-secreted factors alter invasive trophoblast membrane and secreted proteins implying a role for decidual cell regulation of placentation. 2012 PLoS ONE pmid:22359590
Sabari J et al. Fibronectin matrix assembly suppresses dispersal of glioblastoma cells. 2011 PLoS ONE pmid:21980357
Jeong YJ et al. Anti-Osteoarthritic Effects of the Litsea japonica Fruit in a Rat Model of Osteoarthritis Induced by Monosodium Iodoacetate. 2015 PLoS ONE pmid:26244981
Kodali VK et al. A novel disulfide-rich protein motif from avian eggshell membranes. 2011 PLoS ONE pmid:21479176
Zilliges Y et al. The cyanobacterial hepatotoxin microcystin binds to proteins and increases the fitness of microcystis under oxidative stress conditions. 2011 PLoS ONE pmid:21445264
John S et al. Subcellular localization of hexokinases I and II directs the metabolic fate of glucose. 2011 PLoS ONE pmid:21408025
Wang Q et al. Purification and characterization of a CkTLP protein from Cynanchum komarovii seeds that confers antifungal activity. 2011 PLoS ONE pmid:21364945
Al-Jallad HF et al. Plasma membrane factor XIIIA transglutaminase activity regulates osteoblast matrix secretion and deposition by affecting microtubule dynamics. 2011 PLoS ONE pmid:21283799