MeSH term | MeSH ID | Detail |
---|---|---|
Brain Edema | D001929 | 20 associated lipids |
Blood Platelet Disorders | D001791 | 12 associated lipids |
Blindness | D001766 | 6 associated lipids |
Arthritis, Experimental | D001169 | 24 associated lipids |
Iodoacetic acid is a lipid of Fatty Acyls (FA) class. Iodoacetic acid is associated with abnormalities such as Photoreceptor degeneration and Post MI. The involved functions are known as Hypoxia, Glycolysis, Metabolic Inhibition, Oxidation and PTPS activity. Iodoacetic acid often locates in Extracellular, Muscle, Mitochondria, Cytoplasmic matrix and Tissue membrane. The associated genes with Iodoacetic acid are SLC33A1 gene, GTF2I gene, Mutant Proteins, TRIM33 gene and oxytocin, 1-desamino-(O-Et-Tyr)(2)-.
To understand associated biological information of Iodoacetic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Iodoacetic acid is suspected in Photoreceptor degeneration, Post MI and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Iodoacetic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Xiang T et al. | Localization and quantitation of free sulfhydryl in recombinant monoclonal antibodies by differential labeling with 12C and 13C iodoacetic acid and LC-MS analysis. | 2009 | Anal. Chem. | pmid:19722496 |
Chumsae C et al. | Identification and localization of unpaired cysteine residues in monoclonal antibodies by fluorescence labeling and mass spectrometry. | 2009 | Anal. Chem. | pmid:19572546 |
Baragi VM et al. | A new class of potent matrix metalloproteinase 13 inhibitors for potential treatment of osteoarthritis: Evidence of histologic and clinical efficacy without musculoskeletal toxicity in rat models. | 2009 | Arthritis Rheum. | pmid:19565489 |
Suna H et al. | Dysideamine, a new sesquiterpene aminoquinone, protects hippocampal neuronal cells against iodoacetic acid-induced cell death. | 2009 | Bioorg. Med. Chem. | pmid:19414266 |