MeSH term | MeSH ID | Detail |
---|---|---|
Brain Edema | D001929 | 20 associated lipids |
Blood Platelet Disorders | D001791 | 12 associated lipids |
Blindness | D001766 | 6 associated lipids |
Arthritis, Experimental | D001169 | 24 associated lipids |
Iodoacetic acid is a lipid of Fatty Acyls (FA) class. Iodoacetic acid is associated with abnormalities such as Photoreceptor degeneration and Post MI. The involved functions are known as Hypoxia, Glycolysis, Metabolic Inhibition, Oxidation and PTPS activity. Iodoacetic acid often locates in Extracellular, Muscle, Mitochondria, Cytoplasmic matrix and Tissue membrane. The associated genes with Iodoacetic acid are SLC33A1 gene, GTF2I gene, Mutant Proteins, TRIM33 gene and oxytocin, 1-desamino-(O-Et-Tyr)(2)-.
To understand associated biological information of Iodoacetic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Iodoacetic acid is suspected in Photoreceptor degeneration, Post MI and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Iodoacetic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Zhou X et al. | Protective Effect of Edaravone in Primary Cerebellar Granule Neurons against Iodoacetic Acid-Induced Cell Injury. | 2015 | Oxid Med Cell Longev | pmid:26557222 |
Moilanen LJ et al. | Monosodium iodoacetate-induced inflammation and joint pain are reduced in TRPA1 deficient mice--potential role of TRPA1 in osteoarthritis. | 2015 | Osteoarthr. Cartil. | pmid:26521748 |
Bhattacharjee S et al. | Site-Specific Zwitterionic Polymer Conjugates of a Protein Have Long Plasma Circulation. | 2015 | Chembiochem | pmid:26481301 |
James AD et al. | The Plasma Membrane Calcium Pump in Pancreatic Cancer Cells Exhibiting the Warburg Effect Relies on Glycolytic ATP. | 2015 | J. Biol. Chem. | pmid:26294767 |
Rahman W et al. | Electrophysiological evidence for voltage-gated calcium channel 2 (Cav2) modulation of mechano- and thermosensitive spinal neuronal responses in a rat model of osteoarthritis. | 2015 | Neuroscience | pmid:26247695 |
Jeong YJ et al. | Anti-Osteoarthritic Effects of the Litsea japonica Fruit in a Rat Model of Osteoarthritis Induced by Monosodium Iodoacetate. | 2015 | PLoS ONE | pmid:26244981 |
Ogbonna AC et al. | Development of monosodium acetate-induced osteoarthritis and inflammatory pain in ageing mice. | 2015 | Age (Dordr) | pmid:25971876 |
Yassin NZ et al. | Effect of a topical copper indomethacin gel on inflammatory parameters in a rat model of osteoarthritis. | 2015 | Drug Des Devel Ther | pmid:25792809 |
Wang S and Kaltashov IA | Identification of reduction-susceptible disulfide bonds in transferrin by differential alkylation using O(16)/O(18) labeled iodoacetic acid. | 2015 | J. Am. Soc. Mass Spectrom. | pmid:25716754 |
Sagar DR et al. | Dissecting the contribution of knee joint NGF to spinal nociceptive sensitization in a model of OA pain in the rat. | 2015 | Osteoarthr. Cartil. | pmid:25623624 |