Iodoacetic acid

Iodoacetic acid is a lipid of Fatty Acyls (FA) class. Iodoacetic acid is associated with abnormalities such as Photoreceptor degeneration and Post MI. The involved functions are known as Hypoxia, Glycolysis, Metabolic Inhibition, Oxidation and PTPS activity. Iodoacetic acid often locates in Extracellular, Muscle, Mitochondria, Cytoplasmic matrix and Tissue membrane. The associated genes with Iodoacetic acid are SLC33A1 gene, GTF2I gene, Mutant Proteins, TRIM33 gene and oxytocin, 1-desamino-(O-Et-Tyr)(2)-.

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Introduction

To understand associated biological information of Iodoacetic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Iodoacetic acid?

Iodoacetic acid is suspected in Photoreceptor degeneration, Post MI and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Iodoacetic acid

MeSH term MeSH ID Detail
Cumulative Trauma Disorders D012090 2 associated lipids
Monckeberg Medial Calcific Sclerosis D050380 1 associated lipids
Clonorchiasis D003003 1 associated lipids
Osteoarthritis, Spine D055013 2 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Iodoacetic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Iodoacetic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Iodoacetic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Iodoacetic acid?

There are no associated biomedical information in the current reference collection.

What genes are associated with Iodoacetic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Iodoacetic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Iodoacetic acid

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Authors Title Published Journal PubMed Link
Matsuura K et al. Syntheses and self-assembling behaviors of pentagonal conjugates of tryptophane zipper-forming peptide. 2011 Int J Mol Sci pmid:21954352
John S et al. Subcellular localization of hexokinases I and II directs the metabolic fate of glucose. 2011 PLoS ONE pmid:21408025
Plewa MJ et al. Mammalian cell cytotoxicity and genotoxicity of the haloacetic acids, a major class of drinking water disinfection by-products. 2010 Oct-Dec Environ. Mol. Mutagen. pmid:20839218
Fang M et al. Serum N-glycome biomarker for monitoring development of DENA-induced hepatocellular carcinoma in rat. 2010 Mol. Cancer pmid:20704698
Li M et al. A novel function for vimentin: the potential biomarker for predicting melanoma hematogenous metastasis. 2010 J. Exp. Clin. Cancer Res. pmid:20701774
Xu YD et al. The early asthmatic response is associated with glycolysis, calcium binding and mitochondria activity as revealed by proteomic analysis in rats. 2010 Respir. Res. pmid:20691077
Garner OB et al. Endothelial galectin-1 binds to specific glycans on nipah virus fusion protein and inhibits maturation, mobility, and function to block syncytia formation. 2010 PLoS Pathog. pmid:20657665
Swearingen CA et al. A short-term pharmacodynamic model for monitoring aggrecanase activity: injection of monosodium iodoacetate (MIA) in rats and assessment of aggrecan neoepitope release in synovial fluid using novel ELISAs. 2010 Osteoarthr. Cartil. pmid:20633676
Strassle BW et al. Inhibition of osteoclasts prevents cartilage loss and pain in a rat model of degenerative joint disease. 2010 Osteoarthr. Cartil. pmid:20633675
Ochrietor JD et al. The 2M6 antigen is a Müller cell-specific intracellular membrane-associated protein of the sarcolemmal-membrane-associated protein family and is also TopAP. 2010 Mol. Vis. pmid:20577597
Collas A et al. 2-(4-Formyl-2,6-dimeth-oxy-phenoxy)-acetic acid. 2010 Acta Crystallogr Sect E Struct Rep Online pmid:21589164
Evans C [3-(Iodo-acetamido)prop-yl]triphenyl-phospho-nium tetra-phenyl-borate. 2010 Acta Crystallogr Sect E Struct Rep Online pmid:21579806
Qiao YL [Perspective of cervical cancer prevention and control in developing countries and areas]. 2010 Chin J Cancer pmid:20038301
González-Teuber M et al. Glucanases and chitinases as causal agents in the protection of Acacia extrafloral nectar from infestation by phytopathogens. 2010 Plant Physiol. pmid:20023149
Okamoto M and Atsuta Y Cartilage degeneration is associated with augmented chemically-induced joint pain in rats: a pilot study. 2010 Clin. Orthop. Relat. Res. pmid:20013164
Coombs PJ et al. Identification of novel contributions to high-affinity glycoprotein-receptor interactions using engineered ligands. 2010 J. Mol. Biol. pmid:20004209
Liviac D et al. Genotoxicity testing of three monohaloacetic acids in TK6 cells using the cytokinesis-block micronucleus assay. 2010 Mutagenesis pmid:20547559
Miao J et al. 2-Oxo-2,3-dihydro-1H-imidazo[1,2-a]pyridinium iodide. 2010 Acta Crystallogr Sect E Struct Rep Online pmid:21580362
Chambers JE et al. The reduction potential of the active site disulfides of human protein disulfide isomerase limits oxidation of the enzyme by Ero1α. 2010 J. Biol. Chem. pmid:20657012
Wada M and Shirahata A Conformational stabilization of rat s-adenosylmethionine decarboxylase by putrescine. 2010 Biol. Pharm. Bull. pmid:21048303