Iodoacetic acid

Iodoacetic acid is a lipid of Fatty Acyls (FA) class. Iodoacetic acid is associated with abnormalities such as Photoreceptor degeneration and Post MI. The involved functions are known as Hypoxia, Glycolysis, Metabolic Inhibition, Oxidation and PTPS activity. Iodoacetic acid often locates in Extracellular, Muscle, Mitochondria, Cytoplasmic matrix and Tissue membrane. The associated genes with Iodoacetic acid are SLC33A1 gene, GTF2I gene, Mutant Proteins, TRIM33 gene and oxytocin, 1-desamino-(O-Et-Tyr)(2)-.

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Introduction

To understand associated biological information of Iodoacetic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Iodoacetic acid?

Iodoacetic acid is suspected in Photoreceptor degeneration, Post MI and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Iodoacetic acid

MeSH term MeSH ID Detail
Cumulative Trauma Disorders D012090 2 associated lipids
Monckeberg Medial Calcific Sclerosis D050380 1 associated lipids
Clonorchiasis D003003 1 associated lipids
Osteoarthritis, Spine D055013 2 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Iodoacetic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Iodoacetic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Iodoacetic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Iodoacetic acid?

There are no associated biomedical information in the current reference collection.

What genes are associated with Iodoacetic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Iodoacetic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Iodoacetic acid

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Authors Title Published Journal PubMed Link
Mehrotra S et al. Mutational analysis of cysteine 328 and cysteine 368 at the interface of Plasmodium falciparum adenylosuccinate synthetase. 2012 Biochim. Biophys. Acta pmid:22289630
Sotelo-Hitschfeld T et al. Acute feedback control of astrocytic glycolysis by lactate. 2012 Glia pmid:22290492
Lunetta C et al. Impaired expression of insulin-like growth factor-1 system in skeletal muscle of amyotrophic lateral sclerosis patients. 2012 Muscle Nerve pmid:22246875
Xie L et al. Quantitative imaging of cartilage and bone morphology, reactive oxygen species, and vascularization in a rodent model of osteoarthritis. 2012 Arthritis Rheum. pmid:22231023
Izumi M et al. RBCS1A and RBCS3B, two major members within the Arabidopsis RBCS multigene family, function to yield sufficient Rubisco content for leaf photosynthetic capacity. 2012 J. Exp. Bot. pmid:22223809
North SJ et al. Glycomic analysis of human mast cells, eosinophils and basophils. 2012 Glycobiology pmid:21725073
Shimada T et al. Development of iodoacetic acid-based cysteine mass tags: detection enhancement for cysteine-containing peptide by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry. 2012 Anal. Biochem. pmid:22206935
Reyes-Fermín LM et al. Neuroprotective effect of α-mangostin and curcumin against iodoacetate-induced cell death. 2012 Nutr Neurosci pmid:22776704
Raddatz E et al. Differential contribution of mitochondria, NADPH oxidases, and glycolysis to region-specific oxidant stress in the anoxic-reoxygenated embryonic heart. 2011 Am. J. Physiol. Heart Circ. Physiol. pmid:21193588
Stitham J et al. Prostacyclin: an inflammatory paradox. 2011 Front Pharmacol pmid:21687516