Iodoacetic acid

Iodoacetic acid is a lipid of Fatty Acyls (FA) class. Iodoacetic acid is associated with abnormalities such as Photoreceptor degeneration and Post MI. The involved functions are known as Hypoxia, Glycolysis, Metabolic Inhibition, Oxidation and PTPS activity. Iodoacetic acid often locates in Extracellular, Muscle, Mitochondria, Cytoplasmic matrix and Tissue membrane. The associated genes with Iodoacetic acid are SLC33A1 gene, GTF2I gene, Mutant Proteins, TRIM33 gene and oxytocin, 1-desamino-(O-Et-Tyr)(2)-.

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Introduction

To understand associated biological information of Iodoacetic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Iodoacetic acid?

Iodoacetic acid is suspected in Photoreceptor degeneration, Post MI and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Iodoacetic acid

MeSH term MeSH ID Detail
Cumulative Trauma Disorders D012090 2 associated lipids
Monckeberg Medial Calcific Sclerosis D050380 1 associated lipids
Clonorchiasis D003003 1 associated lipids
Osteoarthritis, Spine D055013 2 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Iodoacetic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Iodoacetic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Iodoacetic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Iodoacetic acid?

There are no associated biomedical information in the current reference collection.

What genes are associated with Iodoacetic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Iodoacetic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Iodoacetic acid

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Authors Title Published Journal PubMed Link
Ruff RL and Weissman J Iodoacetate-induced contracture in rat skeletal muscle: possible role of ADP. 1991 Am. J. Physiol. pmid:1951670
Matsumoto Y et al. Creatine kinase kinetics in diabetic cardiomyopathy. 1995 Am. J. Physiol. pmid:7611380
Gores GJ et al. Swelling, reductive stress, and cell death during chemical hypoxia in hepatocytes. 1989 Am. J. Physiol. pmid:2764095
Chih CP et al. Energy metabolism, ion homeostasis, and evoked potentials in anoxic turtle brain. 1989 Am. J. Physiol. pmid:2802002
Conrad CH et al. Outward current and repolarization in hypoxic rat myocardium. 1983 Am. J. Physiol. pmid:6829776
Plishker GA Iodoacetic acid inhibition of calcium-dependent potassium efflux in red blood cells. 1985 Am. J. Physiol. pmid:3993768
SANDOW A and KARCZMAR AG Effect of iodoacetate on changes in muscular latency induced by activity. 1950 Am. J. Physiol. pmid:14789991
Plishker GA Effects of cadmium and zinc on calcium uptake in human red blood cells. 1984 Am. J. Physiol. pmid:6089571
Strewler GJ Release of cAMP from a renal epithelial cell line. 1984 Am. J. Physiol. pmid:6322592
Norris SH and Hersey SJ Stimulation of pepsinogen secretion in permeable isolated gastric glands. 1985 Am. J. Physiol. pmid:3876033
Sumpio BE and Maack T Kinetics, competition, and selectivity of tubular absorption of proteins. 1982 Am. J. Physiol. pmid:7124951
Hartmund T and Gesser H Cardiac force and high-energy phosphates under metabolic inhibition in four ectothermic vertebrates. 1996 Am. J. Physiol. pmid:8897986
Kone BC et al. Cellular pathways of potassium transport in renal inner medullary collecting duct. 1989 Am. J. Physiol. pmid:2539729
Rodríguez-Estrada C Reduced nicotinamide adenine dinucleotide and depolarization in neurons. 1975 Am. J. Physiol. pmid:165729
Lorenz JN and Paul RJ Dependence of Ca2+ channel currents on endogenous and exogenous sources of ATP in portal vein smooth muscle. 1997 Am. J. Physiol. pmid:9124463
Gores GJ et al. Extracellular acidosis delays onset of cell death in ATP-depleted hepatocytes. 1988 Am. J. Physiol. pmid:3421314
Dizon J et al. Metabolic inhibition in the perfused rat heart: evidence for glycolytic requirement for normal sodium homeostasis. 1998 Am. J. Physiol. pmid:9575910
Schwarzbaum PJ et al. Functional role of ecto-ATPase activity in goldfish hepatocytes. 1998 Am. J. Physiol. pmid:9575966
Connett RJ and Hays ET Energy coupling to sodium transport in frog skeletal muscle. 1978 Am. J. Physiol. pmid:307914
Greenwood SL et al. Transtrophoblast and microvillus membrane potential difference in mature intermediate human placental villi. 1993 Am. J. Physiol. pmid:8368275