Iodoacetic acid

Iodoacetic acid is a lipid of Fatty Acyls (FA) class. Iodoacetic acid is associated with abnormalities such as Photoreceptor degeneration and Post MI. The involved functions are known as Hypoxia, Glycolysis, Metabolic Inhibition, Oxidation and PTPS activity. Iodoacetic acid often locates in Extracellular, Muscle, Mitochondria, Cytoplasmic matrix and Tissue membrane. The associated genes with Iodoacetic acid are SLC33A1 gene, GTF2I gene, Mutant Proteins, TRIM33 gene and oxytocin, 1-desamino-(O-Et-Tyr)(2)-.

Cross Reference

Introduction

To understand associated biological information of Iodoacetic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Iodoacetic acid?

Iodoacetic acid is suspected in Photoreceptor degeneration, Post MI and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Iodoacetic acid

MeSH term MeSH ID Detail
Cumulative Trauma Disorders D012090 2 associated lipids
Monckeberg Medial Calcific Sclerosis D050380 1 associated lipids
Clonorchiasis D003003 1 associated lipids
Osteoarthritis, Spine D055013 2 associated lipids
Per page 10 20 50 100 | Total 54

PubChem Associated disorders and diseases

What pathways are associated with Iodoacetic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Iodoacetic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with Iodoacetic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Iodoacetic acid?

There are no associated biomedical information in the current reference collection.

What genes are associated with Iodoacetic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Iodoacetic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Iodoacetic acid

Download all related citations
Per page 10 20 50 100 | Total 2490
Authors Title Published Journal PubMed Link
Wei X et al. Drinking water disinfection byproduct iodoacetic acid induces tumorigenic transformation of NIH3T3 cells. 2013 Environ. Sci. Technol. pmid:23641915
Nan Y et al. Functional evaluation of iodoacetic acid induced photoreceptor degeneration in the cat. 2013 Sci China Life Sci pmid:23657794
More AS et al. Effect of iNOS inhibitor S-methylisothiourea in monosodium iodoacetate-induced osteoathritic pain: implication for osteoarthritis therapy. 2013 Pharmacol. Biochem. Behav. pmid:23287799
La Porta C et al. Role of CB1 and CB2 cannabinoid receptors in the development of joint pain induced by monosodium iodoacetate. 2013 Pain pmid:23199705
Shao H et al. Intra-articular injection of xanthan gum reduces pain and cartilage damage in a rat osteoarthritis model. 2013 Carbohydr Polym pmid:23399228
Cialdai C et al. Comparison between oral and intra-articular antinociceptive effect of dexketoprofen and tramadol combination in monosodium iodoacetate-induced osteoarthritis in rats. 2013 Eur. J. Pharmacol. pmid:23891968
Pals J et al. Human cell toxicogenomic analysis linking reactive oxygen species to the toxicity of monohaloacetic acid drinking water disinfection byproducts. 2013 Environ. Sci. Technol. pmid:24050308
Dhaneshwar S and Patil D Chondromodulating chimeric prodrugs of diacetylrhein: synthesis and evaluation in monoiodoacetate-induced hyperalgesia. 2013 Med Chem pmid:22920092
Liu X et al. An optimized analytical method for the simultaneous detection of iodoform, iodoacetic acid, and other trihalomethanes and haloacetic acids in drinking water. 2013 PLoS ONE pmid:23613747
Ferland CE et al. Antinociceptive effects of eugenol evaluated in a monoiodoacetate-induced osteoarthritis rat model. 2012 Phytother Res pmid:23015356
Camboim EK et al. Defluorination of sodium fluoroacetate by bacteria from soil and plants in Brazil. 2012 ScientificWorldJournal pmid:22619595
Cao S et al. A mitochondria-dependent pathway mediates the apoptosis of GSE-induced yeast. 2012 PLoS ONE pmid:22403727
Gallis JL et al. Resveratrol plus ethanol counteract the ethanol-induced impairment of energy metabolism: ³¹P NMR study of ATP and sn-glycerol-3-phosphate on isolated and perfused rat liver. 2012 Pharmacol. Res. pmid:22227530
Li Y et al. Analysis of iodinated haloacetic acids in drinking water by reversed-phase liquid chromatography/electrospray ionization/tandem mass spectrometry with large volume direct aqueous injection. 2012 J Chromatogr A pmid:22658134
Cardador MJ and Gallego M Development of a method for the quantitation of chloro-, bromo-, and iodoacetic acids in alcoholic beverages. 2012 J. Agric. Food Chem. pmid:22225467
Wang XD et al. Progression of cartilage degradation, bone resorption and pain in rat temporomandibular joint osteoarthritis induced by injection of iodoacetate. 2012 PLoS ONE pmid:22984604
Kaneda T et al. Key role of glycogen storage in high K+-induced contraction of the smooth muscles of the bovine trachea. 2012 J. Vet. Med. Sci. pmid:22673054
Mikulíková K et al. Study of saiga horn using high-performance liquid chromatography with mass spectrometry. 2012 ScientificWorldJournal pmid:22629195
Trivedi M et al. Improving the stability of the EC1 domain of E-cadherin by thiol alkylation of the cysteine residue. 2012 Int J Pharm pmid:22531851
Du J et al. The protein partners of GTP cyclohydrolase I in rat organs. 2012 PLoS ONE pmid:22479495
Kim JK et al. Effect of GCSB-5, a Herbal Formulation, on Monosodium Iodoacetate-Induced Osteoarthritis in Rats. 2012 Evid Based Complement Alternat Med pmid:22474519
Thakur M et al. Characterisation of a peripheral neuropathic component of the rat monoiodoacetate model of osteoarthritis. 2012 PLoS ONE pmid:22470467
Sun L et al. N-acetylcysteine protects against apoptosis through modulation of group I metabotropic glutamate receptor activity. 2012 PLoS ONE pmid:22442667
Jia D et al. Fibronectin matrix-mediated cohesion suppresses invasion of prostate cancer cells. 2012 BMC Cancer pmid:22433434
Weinans H Periarticular bone changes in osteoarthritis. 2012 HSS J pmid:22423223
Okun A et al. Afferent drive elicits ongoing pain in a model of advanced osteoarthritis. 2012 Pain pmid:22387095
Sixt SU et al. Distinct proteasome subpopulations in the alveolar space of patients with the acute respiratory distress syndrome. 2012 Mediators Inflamm. pmid:22363101
Menkhorst EM et al. Decidual-secreted factors alter invasive trophoblast membrane and secreted proteins implying a role for decidual cell regulation of placentation. 2012 PLoS ONE pmid:22359590
Kelly S et al. Spontaneous firing in C-fibers and increased mechanical sensitivity in A-fibers of knee joint-associated mechanoreceptive primary afferent neurones during MIA-induced osteoarthritis in the rat. 2012 Osteoarthr. Cartil. pmid:22285737
Mehrotra S et al. Mutational analysis of cysteine 328 and cysteine 368 at the interface of Plasmodium falciparum adenylosuccinate synthetase. 2012 Biochim. Biophys. Acta pmid:22289630
Ahn CM et al. Decreased lung hyaluronan in a model of ARDS in the rat: effect of an inhibitor of leukocyte elastase. 2012 Ups. J. Med. Sci. pmid:22283425
Sotelo-Hitschfeld T et al. Acute feedback control of astrocytic glycolysis by lactate. 2012 Glia pmid:22290492
Yu MK et al. Targeting strategies for multifunctional nanoparticles in cancer imaging and therapy. 2012 Theranostics pmid:22272217
Lunetta C et al. Impaired expression of insulin-like growth factor-1 system in skeletal muscle of amyotrophic lateral sclerosis patients. 2012 Muscle Nerve pmid:22246875
Xie L et al. Quantitative imaging of cartilage and bone morphology, reactive oxygen species, and vascularization in a rodent model of osteoarthritis. 2012 Arthritis Rheum. pmid:22231023
Izumi M et al. RBCS1A and RBCS3B, two major members within the Arabidopsis RBCS multigene family, function to yield sufficient Rubisco content for leaf photosynthetic capacity. 2012 J. Exp. Bot. pmid:22223809
Fiaschi T et al. Redox Regulation of Nonmuscle Myosin Heavy Chain during Integrin Engagement. 2012 J Signal Transduct pmid:22220276
Vincent A et al. parkin-induced defects in neurophysiology and locomotion are generated by metabolic dysfunction and not oxidative stress. 2012 Hum. Mol. Genet. pmid:22215442
Wang H et al. Proteomic analysis of early-responsive redox-sensitive proteins in Arabidopsis. 2012 J. Proteome Res. pmid:22050424
North SJ et al. Glycomic analysis of human mast cells, eosinophils and basophils. 2012 Glycobiology pmid:21725073
Wang S and Kaltashov IA A new strategy of using O18-labeled iodoacetic acid for mass spectrometry-based protein quantitation. 2012 J. Am. Soc. Mass Spectrom. pmid:22562395
Lin X et al. B2A peptide induces chondrogenic differentiation in vitro and enhances cartilage repair in rats. 2012 J. Orthop. Res. pmid:22271086
Izumi M et al. Local ASIC3 modulates pain and disease progression in a rat model of osteoarthritis. 2012 J. Biomed. Sci. pmid:22909215
Ashkavand Z et al. Silymarin potentiates the anti-inflammatory effects of Celecoxib on chemically induced osteoarthritis in rats. 2012 Phytomedicine pmid:22925727
Schuelert N and McDougall JJ Involvement of Nav 1.8 sodium ion channels in the transduction of mechanical pain in a rodent model of osteoarthritis. 2012 Arthritis Res. Ther. pmid:22225591
Shimada T et al. Development of iodoacetic acid-based cysteine mass tags: detection enhancement for cysteine-containing peptide by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry. 2012 Anal. Biochem. pmid:22206935
Reyes-Fermín LM et al. Neuroprotective effect of α-mangostin and curcumin against iodoacetate-induced cell death. 2012 Nutr Neurosci pmid:22776704
Ferreira-Gomes J et al. Dose-dependent expression of neuronal injury markers during experimental osteoarthritis induced by monoiodoacetate in the rat. 2012 Mol Pain pmid:22769424
Noel JM et al. Iodoacetic acid, but not sodium iodate, creates an inducible swine model of photoreceptor damage. 2012 Exp. Eye Res. pmid:22251455
Hardes K et al. Design, synthesis, and characterization of chromogenic substrates of coagulation factor XIIIa. 2012 Anal. Biochem. pmid:22683584