Iodoacetic acid

Iodoacetic acid is a lipid of Fatty Acyls (FA) class. Iodoacetic acid is associated with abnormalities such as Photoreceptor degeneration and Post MI. The involved functions are known as Hypoxia, Glycolysis, Metabolic Inhibition, Oxidation and PTPS activity. Iodoacetic acid often locates in Extracellular, Muscle, Mitochondria, Cytoplasmic matrix and Tissue membrane. The associated genes with Iodoacetic acid are SLC33A1 gene, GTF2I gene, Mutant Proteins, TRIM33 gene and oxytocin, 1-desamino-(O-Et-Tyr)(2)-.

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Introduction

To understand associated biological information of Iodoacetic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Iodoacetic acid?

Iodoacetic acid is suspected in Photoreceptor degeneration, Post MI and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Iodoacetic acid

MeSH term MeSH ID Detail
Cumulative Trauma Disorders D012090 2 associated lipids
Monckeberg Medial Calcific Sclerosis D050380 1 associated lipids
Clonorchiasis D003003 1 associated lipids
Osteoarthritis, Spine D055013 2 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Iodoacetic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Iodoacetic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Iodoacetic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Iodoacetic acid?

There are no associated biomedical information in the current reference collection.

What genes are associated with Iodoacetic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Iodoacetic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Iodoacetic acid

Download all related citations
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Authors Title Published Journal PubMed Link
Bazzocco S et al. Highly Expressed Genes in Rapidly Proliferating Tumor Cells as New Targets for Colorectal Cancer Treatment. 2015 Clin. Cancer Res. pmid:25944804
Procházka E et al. In Vitro Cytotoxicity and Adaptive Stress Responses to Selected Haloacetic Acid and Halobenzoquinone Water Disinfection Byproducts. 2015 Chem. Res. Toxicol. pmid:26327680
Taniguchi A et al. Decreased calcitonin gene-related peptide expression in the dorsal root ganglia of TNF-deficient mice in a monoiodoacetate-induced knee osteoarthritis model. 2015 Int J Clin Exp Pathol pmid:26722492
Xu YK et al. The role of MCP-1-CCR2 ligand-receptor axis in chondrocyte degradation and disease progress in knee osteoarthritis. 2015 Biol. Res. pmid:26578310
Zhou X et al. Protective Effect of Edaravone in Primary Cerebellar Granule Neurons against Iodoacetic Acid-Induced Cell Injury. 2015 Oxid Med Cell Longev pmid:26557222
Ogbonna AC et al. Development of monosodium acetate-induced osteoarthritis and inflammatory pain in ageing mice. 2015 Age (Dordr) pmid:25971876
Yassin NZ et al. Effect of a topical copper indomethacin gel on inflammatory parameters in a rat model of osteoarthritis. 2015 Drug Des Devel Ther pmid:25792809
Wang S and Kaltashov IA Identification of reduction-susceptible disulfide bonds in transferrin by differential alkylation using O(16)/O(18) labeled iodoacetic acid. 2015 J. Am. Soc. Mass Spectrom. pmid:25716754
Sagar DR et al. Dissecting the contribution of knee joint NGF to spinal nociceptive sensitization in a model of OA pain in the rat. 2015 Osteoarthr. Cartil. pmid:25623624
Liu Y et al. Activation of α7 nicotinic acetylcholine receptors prevents monosodium iodoacetate-induced osteoarthritis in rats. 2015 Cell. Physiol. Biochem. pmid:25613062