Iodoacetic acid

Iodoacetic acid is a lipid of Fatty Acyls (FA) class. Iodoacetic acid is associated with abnormalities such as Photoreceptor degeneration and Post MI. The involved functions are known as Hypoxia, Glycolysis, Metabolic Inhibition, Oxidation and PTPS activity. Iodoacetic acid often locates in Extracellular, Muscle, Mitochondria, Cytoplasmic matrix and Tissue membrane. The associated genes with Iodoacetic acid are SLC33A1 gene, GTF2I gene, Mutant Proteins, TRIM33 gene and oxytocin, 1-desamino-(O-Et-Tyr)(2)-.

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Introduction

To understand associated biological information of Iodoacetic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Iodoacetic acid?

Iodoacetic acid is suspected in Photoreceptor degeneration, Post MI and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Iodoacetic acid

MeSH term MeSH ID Detail
Cumulative Trauma Disorders D012090 2 associated lipids
Monckeberg Medial Calcific Sclerosis D050380 1 associated lipids
Clonorchiasis D003003 1 associated lipids
Osteoarthritis, Spine D055013 2 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Iodoacetic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Iodoacetic acid?

Related references are published most in these journals:

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What functions are associated with Iodoacetic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Iodoacetic acid?

There are no associated biomedical information in the current reference collection.

What genes are associated with Iodoacetic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Iodoacetic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Iodoacetic acid

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Authors Title Published Journal PubMed Link
Bell SD et al. RNA molecules that bind to and inhibit the active site of a tyrosine phosphatase. 1998 J. Biol. Chem. pmid:9603938
Jensen PK et al. Monitoring protein refolding induced by disulfide formation using capillary isoelectric focusing-electrospray ionization mass spectrometry. 1998 Anal. Chem. pmid:9608843
Bakken IJ et al. [U-13C] aspartate metabolism in cultured cortical astrocytes and cerebellar granule neurons studied by NMR spectroscopy. 1998 Glia pmid:9633811
Hilliard CA et al. Chromosome aberrations in vitro related to cytotoxicity of nonmutagenic chemicals and metabolic poisons. 1998 Environ. Mol. Mutagen. pmid:9654240
Shin HH and Choi HS Purification and characterization of cysteine protease from Pleurotus ostreatus. 1998 Biosci. Biotechnol. Biochem. pmid:9720226
Lancaster MK and Harrison SM Changes in contraction, cytosolic Ca2+ and pH during metabolic inhibition and upon restoration of mitochondrial respiration in rat ventricular myocytes. 1998 Exp. Physiol. pmid:9639344
Kinsland C et al. Overexpression of recombinant proteins with a C-terminal thiocarboxylate: implications for protein semisynthesis and thiamin biosynthesis. 1998 Protein Sci. pmid:10082383
Holdobina OV [Changes in the total calcium content and in the activity of alkaline phosphatase and gamma-glutamyltransferase in the blood serum of rats with Mönckeberg's experimental arteriosclerosis]. 1998 Fiziol Zh pmid:9619411
Gilmour KM et al. Transepithelial potential of cultured branchial epithelia from rainbow trout under symmetrical conditions. 1998 In Vitro Cell. Dev. Biol. Anim. pmid:9661043
Post JA et al. pHe, [Ca2+]e, and cell death during metabolic inhibition: role of phospholipase A2 and sarcolemmal phospholipids. 1998 Am. J. Physiol. pmid:9458847
Prakash O and Bhushan G A study of inhibition of urease from seeds of the water melon (Citrullus vulgaris). 1998 J. Enzym. Inhib. pmid:9879515
Vega MC et al. The three-dimensional structure of Cys-47-modified mouse liver glutathione S-transferase P1-1. Carboxymethylation dramatically decreases the affinity for glutathione and is associated with a loss of electron density in the alphaB-310B region. 1998 J. Biol. Chem. pmid:9446594
Bakken IJ et al. [U-13C]glutamate metabolism in astrocytes during hypoglycemia and hypoxia. 1998 J. Neurosci. Res. pmid:9512008
Dizon J et al. Metabolic inhibition in the perfused rat heart: evidence for glycolytic requirement for normal sodium homeostasis. 1998 Am. J. Physiol. pmid:9575910
Schwarzbaum PJ et al. Functional role of ecto-ATPase activity in goldfish hepatocytes. 1998 Am. J. Physiol. pmid:9575966
Parry S et al. Identification of active-site histidine residues of a self-incompatibility ribonuclease from a wild tomato. 1997 Plant Physiol. pmid:9414554
Vezzoli A et al. Quantitative analysis of anaerobic metabolism in resting anoxic muscle by 31P and 1H MRS. 1997 Biochim. Biophys. Acta pmid:9452766
Agalakova NI et al. Differential effects of glycolytic and oxidative metabolism blockers on the Na-K pump in erythrocytes of the frog, Rana temporaria. 1997 J. Comp. Physiol. B, Biochem. Syst. Environ. Physiol. pmid:9404018
Nakayama S et al. Consequences of metabolic inhibition in smooth muscle isolated from guinea-pig stomach. 1997 J. Physiol. (Lond.) pmid:9409485
Kim H et al. Evidence for the essential histidine residues in geranylgeranyl transferase type I from bovine testis. 1997 Biochem. Mol. Biol. Int. pmid:9350353
Ness LS et al. Survival of Escherichia coli cells exposed to iodoacetate and chlorodinitrobenzene is independent of the glutathione-gated K+ efflux systems KefB and KefC. 1997 Appl. Environ. Microbiol. pmid:9327573
Sugimoto S et al. [A procedure for electroretinogram (ERG) recording in mice--effect of monoiodoacetic acid on the ERG in pigmented mice]. 1997 J Toxicol Sci pmid:9430091
Wu ML et al. Capacitative Ca2+ influx in glial cells is inhibited by glycolytic inhibitors. 1997 Glia pmid:9383040
Huang YC et al. Identification of the subunits and target peptides of pig heart NAD-specific isocitrate dehydrogenase modified by the affinity label 8-(4-bromo-2,3-dioxobutylthio)NAD. 1997 Arch. Biochem. Biophys. pmid:9390193
Izumi Y et al. Endogenous monocarboxylates sustain hippocampal synaptic function and morphological integrity during energy deprivation. 1997 J. Neurosci. pmid:9391000
Marrone L and Viswanatha T Effect of selective cysteine --> alanine replacements on the catalytic functions of lysine: N6-hydroxylase. 1997 Biochim. Biophys. Acta pmid:9434117
Xu W et al. Identification of critical positive charges in XIP, the Na/Ca exchange inhibitory peptide. 1997 Arch. Biochem. Biophys. pmid:9169015
Rangarajan M et al. Biochemical characterization of the arginine-specific proteases of Porphyromonas gingivalis W50 suggests a common precursor. 1997 Biochem. J. pmid:9169603
Fang HK et al. Cardiac contractile function during coronary stenosis in dogs: association of adenosine in glycolytic dependence. 1997 Am. J. Physiol. pmid:9176286
Bender AS et al. The rapid L- and D-aspartate uptake in cultured astrocytes. 1997 Neurochem. Res. pmid:9178956
Burton FL and Smith GL The effect of cromakalim on intracellular [Ca2+] in isolated rat skeletal muscle during fatigue and metabolic blockade. 1997 Exp. Physiol. pmid:9179567
Kuwata K et al. Cross-relaxation times of normal and biochemically induced osteoarthritic rabbit knee cartilages. 1997 Jpn. J. Physiol. pmid:9271160
Rego AC et al. Adenosine triphosphate degradation products after oxidative stress and metabolic dysfunction in cultured retinal cells. 1997 J. Neurochem. pmid:9282947
Himmelreich U and Kuchel PW 13C-NMR studies of transmembrane electron transfer to extracellular ferricyanide in human erythrocytes. 1997 Eur. J. Biochem. pmid:9219520
Izumi Y et al. Monocarboxylates (pyruvate and lactate) as alternative energy substrates for the induction of long-term potentiation in rat hippocampal slices. 1997 Neurosci. Lett. pmid:9292881
Monika EM et al. A thioreduction pathway tethered to the membrane for periplasmic cytochromes c biogenesis; in vitro and in vivo studies. 1997 J. Mol. Biol. pmid:9299319
Santori G et al. Different efficacy of iodoacetic acid and N-ethylmaleimide in high-performance liquid chromatographic measurement of liver glutathione. 1997 J. Chromatogr. B Biomed. Sci. Appl. pmid:9300880
Gramolini A and Renaud JM Blocking ATP-sensitive K+ channel during metabolic inhibition impairs muscle contractility. 1997 Am. J. Physiol. pmid:9227423
Matthews RT et al. Iodoacetate produces striatal excitotoxic lesions. 1997 J. Neurochem. pmid:9202321
Xie LH et al. Development of inwardly rectifying K+ channel family in rat ventricular myocytes. 1997 Am. J. Physiol. pmid:9139958
Cappelli-Bigazzi M et al. Role of oxidative metabolism on endothelium-dependent vascular relaxation of isolated vessels. 1997 J. Mol. Cell. Cardiol. pmid:9152848
Carne AF and U S Chemical modification of proteins for sequence analysis. 1997 Methods Mol. Biol. pmid:9116830
Kajikawa H et al. Glucose transport by mixed ruminal bacteria from a cow. 1997 Appl. Environ. Microbiol. pmid:9143117
Peretz M et al. Cysteine reactivity in Thermoanaerobacter brockii alcohol dehydrogenase. 1997 Protein Sci. pmid:9144779
Nasu T and Baba K Mechanics of manganese ions-induced contraction of ileal longitudinal muscle in Ca(2+)-free, high-K+ medium. 1997 Gen. Pharmacol. pmid:9147016
Lorenz JN and Paul RJ Dependence of Ca2+ channel currents on endogenous and exogenous sources of ATP in portal vein smooth muscle. 1997 Am. J. Physiol. pmid:9124463
Loeuille D et al. In vitro magnetic resonance microimaging of experimental osteoarthritis in the rat knee joint. 1997 J. Rheumatol. pmid:9002024
Gali RR and Board PG Identification of an essential cysteine residue in human glutathione synthase. 1997 Biochem. J. pmid:9003420
Oda Y et al. Purification and properties of poly(3-hydroxybutyrate) depolymerase from the fungus Paecilomyces lilacinus D218. 1997 Curr. Microbiol. pmid:9058543
Santos RM et al. Bursting electrical activity generated in the presence of KATP channel blockers. Pharmacology, sensitivity to intracellular pH and modulation by glucose metabolism. 1997 Adv. Exp. Med. Biol. pmid:9544253
Jornot L et al. Modulation of the DNA binding activity of transcription factors CREP, NFkappaB and HSF by H2O2 and TNF alpha. Differences between in vivo and in vitro effects. 1997 FEBS Lett. pmid:9373190
Chen CJ et al. Characterization and purification of a lipoxygenase inhibitor in human epidermoid carcinoma A431 cells. 1997 Biochem. J. pmid:9355752
Waki A et al. Effects of antitumor agents on 3H-2-deoxyglucose uptake in tumor cells and their relationship with the main targets of the antitumor agents. 1997 Ann Nucl Med pmid:9310165
Clarke KA et al. Gait analysis in a rat model of osteoarthrosis. 1997 Physiol. Behav. pmid:9333186
Chandra A et al. Modification of aldose reductase by S-nitrosoglutathione. 1997 Biochemistry pmid:9398310
Umbach AL and Siedow JN The reaction of the soybean cotyledon mitochondrial cyanide-resistant oxidase with sulfhydryl reagents suggests that alpha-keto acid activation involves the formation of a thiohemiacetal. 1996 J. Biol. Chem. pmid:8798784
Han Z et al. DNA-dependent protein kinase is a target for a CPP32-like apoptotic protease. 1996 J. Biol. Chem. pmid:8798786
Wu Y et al. Changes in membrane properties during energy depletion-induced cell injury studied with fluorescence microscopy. 1996 Biophys. J. pmid:8804592
Kanaani J et al. Probing the active site of Tritrichomonas foetus hypoxanthine-guanine-xanthine phosphoribosyltransferase using covalent modification of cysteine residues. 1996 Eur. J. Biochem. pmid:8774725
Hegy GB et al. Carboxymethylation of the human estrogen receptor ligand-binding domain-estradiol complex: HPLC/ESMS peptide mapping shows that cysteine 447 does not react with iodoacetic acid. 1996 Steroids pmid:8776799
Barrigon S et al. Characterization of the calcium overload in cultured neonatal rat cardiomyocytes under metabolic inhibition. 1996 J. Mol. Cell. Cardiol. pmid:8782074
Dekker LR et al. Intracellular Ca2+, intercellular electrical coupling, and mechanical activity in ischemic rabbit papillary muscle. Effects of preconditioning and metabolic blockade. 1996 Circ. Res. pmid:8756000
Lawson SL et al. Effects of both shortening and lengthening the active site nucleophile of Bacillus circulans xylanase on catalytic activity. 1996 Biochemistry pmid:8756474
Collinson IR et al. The F1F0-ATPase complex from bovine heart mitochondria: the molar ratio of the subunits in the stalk region linking the F1 and F0 domains. 1996 Biochemistry pmid:8823202
Chew A et al. Mutations in a putative zinc-binding domain inactivate the mitochondrial intermediate peptidase. 1996 Biochem. Biophys. Res. Commun. pmid:8831696
Xu M and Akabas MH Identification of channel-lining residues in the M2 membrane-spanning segment of the GABA(A) receptor alpha1 subunit. 1996 J. Gen. Physiol. pmid:8833341
Godeas C et al. Rat testis mitochondrial phospholipid hydroperoxide glutathione peroxidase does not protect endogenous vitamin E against Fe2+-induced (lipo)peroxidation. 1996 Biochem. Mol. Med. pmid:8812743
Ballanyi K et al. Functional relevance of anaerobic metabolism in the isolated respiratory network of newborn rats. 1996 Pflugers Arch. pmid:8764977
Ito Y et al. Oxidative stress increases glyceraldehyde-3-phosphate dehydrogenase mRNA levels in isolated rabbit aorta. 1996 Am. J. Physiol. pmid:8769737
Wu Y et al. Alterations in reactive oxygen, pH, and calcium in astrocytoma cells during lethal injury. 1996 Am. J. Physiol. pmid:8772436
Andrés MI et al. Comparative effects of the metabolic inhibitors 2,4-dinitrophenol and iodoacetate on mouse neuroblastoma cells in vitro. 1996 Toxicology pmid:8658553
Reaven E et al. Intracellular events in the "selective" transport of lipoprotein-derived cholesteryl esters. 1996 J. Biol. Chem. pmid:8663101
Morel MH and Bonicel J Determination of the number of cysteine residues in high molecular weight subunits of wheat glutenin. 1996 Electrophoresis pmid:8740165
Boehm EA et al. The utilisation of creatine and its analogues by cytosolic and mitochondrial creatine kinase. 1996 Biochim. Biophys. Acta pmid:8664304
Barnett DK and Bavister BD Inhibitory effect of glucose and phosphate on the second cleavage division of hamster embryos: is it linked to metabolism? 1996 Hum. Reprod. pmid:8671182
Six S et al. Reactivity of the N-terminal cysteine residues in active and inactive forms of FNR, and O2-responsive, Fe containing transcriptional regulator of Escherichia coli. 1996 J. Inorg. Biochem. pmid:8729797
Raia CA et al. Activation of Sulfolobus solfataricus alcohol dehydrogenase by modification of cysteine residue 38 with iodoacetic acid. 1996 Biochemistry pmid:8555238
Lash LH et al. ATP depletion by iodoacetate and cyanide in renal distal tubular cells. 1996 J. Pharmacol. Exp. Ther. pmid:8558430
Webster DR and Oxford MG Regulation of cytoplasmic tubulin carboxypeptidase activity in vitro by cations and sulfhydryl-modifying compounds. 1996 J. Cell. Biochem. pmid:8867817
Hartmund T and Gesser H Cardiac force and high-energy phosphates under metabolic inhibition in four ectothermic vertebrates. 1996 Am. J. Physiol. pmid:8897986
Malek A et al. Energy charge monitoring via magnetic resonance spectroscopy 31P in the perfused human placenta: effects of cadmium, dinitrophenol and iodoacetate. 1996 Placenta pmid:8899879
Dux E et al. Early ultrastructural changes after brief histotoxic hypoxia in cultured cortical and hippocampal CA1 neurons. 1996 Acta Neuropathol. pmid:8960310
Wells JE and Russell JB The effect of growth and starvation on the lysis of the ruminal cellulolytic bacterium Fibrobacter succinogenes. 1996 Appl. Environ. Microbiol. pmid:8919795
Mackert BM et al. Anoxia in vitro does not induce neuronal swelling or death. 1996 J. Neurol. Sci. pmid:8836970
Kelly MJ and Richardson W Possible mechanisms for the protective action of alpha-tocopherol in vascular hypoxia. 1996 J Auton Pharmacol pmid:8842869
Tozawa K et al. Unusual pKa of the carboxylate at the putative catalytic position of the thermophilic F1-ATPase beta subunit determined by 13C-NMR. 1996 FEBS Lett. pmid:8941727
Guzzo A et al. Analysis of the region between amino acids 30 and 42 of intact UmuD by a monocysteine approach. 1996 J. Bacteriol. pmid:8955415
López de Heredia M et al. The integrity of thiol groups is essential for catalytic efficiency of rat liver cholesterol ester hydrolase either in microsomal membranes or after solubilization. 1996 Enzyme Protein pmid:9252786
Reshef A et al. Preconditioning of primary rat neuronal cultures against ischemic injury: characterization of the "time window of protection'. 1996 Brain Res. pmid:9001730
Saransaari P and Oja SS Taurine and neural cell damage. Transport of taurine in adult and developing mice. 1996 Adv. Exp. Med. Biol. pmid:8915386
Dadlez M and Kim PS Rapid formation of the native 14-38 disulfide bond in the early stages of BPTI folding. 1996 Biochemistry pmid:8973187
Nawaz MS et al. Physical, biochemical, and immunological characterization of a thermostable amidase from Klebsiella pneumoniae NCTR 1. 1996 J. Bacteriol. pmid:8636044
Matsushita M et al. Isoflurane preserves adenosine triphosphate levels in anoxic isolated rat hepatocytes by stimulating glycolytic adenosine triphosphate formation. 1996 Anesth. Analg. pmid:8638802
Wu L and Zhang ZY Probing the function of Asp128 in the lower molecular weight protein-tyrosine phosphatase-catalyzed reaction. A pre-steady-state and steady-state kinetic investigation. 1996 Biochemistry pmid:8611532
Grifantini R et al. Topological mapping of the cysteine residues of N-carbamyl-D-amino-acid amidohydrolase and their role in enzymatic activity. 1996 J. Biol. Chem. pmid:8621596
Jones MD et al. Refolding and oxidation of recombinant human stem cell factor produced in Escherichia coli. 1996 J. Biol. Chem. pmid:8626682
Peltier JB and Rossignol M Auxin-induced differential sensitivity of the H+-ATPase in plasma membrane subfractions from tobacco cells. 1996 Biochem. Biophys. Res. Commun. pmid:8605015
Matsumoto Y et al. Creatine kinase kinetics in diabetic cardiomyopathy. 1995 Am. J. Physiol. pmid:7611380
Polliotti BM et al. Culture of first-trimester and full-term human chorionic villus explants: role of human chorionic gonadotropin and human placental lactogen as a viability index. 1995 Early Pregnancy pmid:9363259
Koekemoer TC et al. Isolation and characterization of adipose tissue glycerol-3-phosphate dehydrogenase. 1995 Int. J. Biochem. Cell Biol. pmid:7671141