Iodoacetic acid

Iodoacetic acid is a lipid of Fatty Acyls (FA) class. Iodoacetic acid is associated with abnormalities such as Photoreceptor degeneration and Post MI. The involved functions are known as Hypoxia, Glycolysis, Metabolic Inhibition, Oxidation and PTPS activity. Iodoacetic acid often locates in Extracellular, Muscle, Mitochondria, Cytoplasmic matrix and Tissue membrane. The associated genes with Iodoacetic acid are SLC33A1 gene, GTF2I gene, Mutant Proteins, TRIM33 gene and oxytocin, 1-desamino-(O-Et-Tyr)(2)-.

Cross Reference

Introduction

To understand associated biological information of Iodoacetic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Iodoacetic acid?

Iodoacetic acid is suspected in Photoreceptor degeneration, Post MI and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Iodoacetic acid

MeSH term MeSH ID Detail
Cumulative Trauma Disorders D012090 2 associated lipids
Monckeberg Medial Calcific Sclerosis D050380 1 associated lipids
Clonorchiasis D003003 1 associated lipids
Osteoarthritis, Spine D055013 2 associated lipids
Per page 10 20 50 100 | Total 54

PubChem Associated disorders and diseases

What pathways are associated with Iodoacetic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Iodoacetic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with Iodoacetic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Iodoacetic acid?

There are no associated biomedical information in the current reference collection.

What genes are associated with Iodoacetic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Iodoacetic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Iodoacetic acid

Download all related citations
Per page 10 20 50 100 | Total 2490
Authors Title Published Journal PubMed Link
Gandhi S et al. PINK1-associated Parkinson's disease is caused by neuronal vulnerability to calcium-induced cell death. 2009 Mol. Cell pmid:19285945
Fang M et al. Serum N-glycome biomarker for monitoring development of DENA-induced hepatocellular carcinoma in rat. 2010 Mol. Cancer pmid:20704698
Gol'dshteÄ­n BN et al. [Kinetic manifestations of the interaction of active centers in swine skeletal muscle D-glyceraldehyde-3-phosphate dehydrogenase]. 1976 Jan-Feb Mol. Biol. (Mosk.) pmid:183104
Lockwood BC et al. The use of a highly sensitive electrophoretic method to compare the proteinases of trichomonads. 1987 Mol. Biochem. Parasitol. pmid:3302703
Gbenle GO and Akinrimisi EO Studies on the catalytic properties of the calcium-dependent endoribonuclease of Trypanosoma brucei cytoplasm. 1982 Mol. Biochem. Parasitol. pmid:6178971
Aoki T et al. Mechanism of inactivation of a Fasciola proteolytic enzyme by peptide aldehydes and alkylating agents. 1983 Mol. Biochem. Parasitol. pmid:6877285
Swamy KH and Jaffe JJ Isolation, partial purification and some properties of two acid proteases from adult Dirofilaria immitis. 1983 Mol. Biochem. Parasitol. pmid:6366544
North MJ and Coombs GH Proteinases of Leishmania mexicana amastigotes and promastigotes: analysis by gel electrophoresis. 1981 Mol. Biochem. Parasitol. pmid:7029274
McGaraughty S et al. TRPA1 modulation of spontaneous and mechanically evoked firing of spinal neurons in uninjured, osteoarthritic, and inflamed rats. 2010 Mol Pain pmid:20205719
Sagar DR et al. The contribution of spinal glial cells to chronic pain behaviour in the monosodium iodoacetate model of osteoarthritic pain. 2011 Mol Pain pmid:22093915
Rahman W et al. Descending serotonergic facilitation and the antinociceptive effects of pregabalin in a rat model of osteoarthritic pain. 2009 Mol Pain pmid:19664204
Harvey VL and Dickenson AH Behavioural and electrophysiological characterisation of experimentally induced osteoarthritis and neuropathy in C57Bl/6 mice. 2009 Mol Pain pmid:19379487
Neugebauer V et al. Techniques for assessing knee joint pain in arthritis. 2007 Mol Pain pmid:17391515
Abaei M et al. Neural correlates of hyperalgesia in the monosodium iodoacetate model of osteoarthritis pain. 2016 Mol Pain pmid:27068285
Lee Y et al. Monosodium iodoacetate-induced joint pain is associated with increased phosphorylation of mitogen activated protein kinases in the rat spinal cord. 2011 Mol Pain pmid:21599960
Ferreira-Gomes J et al. Dose-dependent expression of neuronal injury markers during experimental osteoarthritis induced by monoiodoacetate in the rat. 2012 Mol Pain pmid:22769424
Sweet C and Halliwell G Regulation of cellvibriocin activity. 1977 Microbios pmid:617829
el-Rahmany TA Comparison of L-aspartate 4-carboxy-lyases of Cunninghamella elegans and Penicillium citrinum. 1994 Microbiol. Res. pmid:7987614
Sakurai J et al. Effect of oxidizing agents and sulfhydryl group reagents on beta toxin from Clostridium perfringens type C. 1980 Microbiol. Immunol. pmid:6251344
Yoshimura G et al. Identification and molecular characterization of an N-Acetylmuraminidase, Aml, involved in Streptococcus mutans cell separation. 2006 Microbiol. Immunol. pmid:16985295
Carne AF and U S Chemical modification of proteins for sequence analysis. 1997 Methods Mol. Biol. pmid:9116830
Meng TC et al. Development of a modified in-gel assay to identify protein tyrosine phosphatases that are oxidized and inactivated in vivo. 2005 Methods pmid:15588983
Creighton TE Disulfide bond formation in proteins. 1984 Meth. Enzymol. pmid:6503716
Inglis AS Single hydrolysis method for all amino acids, including cysteine and tryptophan. 1983 Meth. Enzymol. pmid:6855579
Kimura M et al. Detection of carboxymethylmetallothionein by sodium dodecyl sulfate-polyacrylamide gel electrophoresis. 1991 Meth. Enzymol. pmid:1779774
Thomas JA et al. Analysis of cells and tissues for S-thiolation of specific proteins. 1995 Meth. Enzymol. pmid:7651223
Dalal P and Romani A Adenosine triphosphate depletion by cyanide results in a Na(+)-dependent Mg(2+) extrusion from liver cells. 2010 Metab. Clin. Exp. pmid:20494376
Shiroyama K et al. Glucose loading during primary culture has opposite effects on the viability of hepatocytes exposed to potassium cyanide and to iodoacetic acid. 2001 Metab. Clin. Exp. pmid:11230789
Young EF et al. Structural characterization of phospholamban in cardiac sarcoplasmic reticulum membranes by cross-linking. 1989 Membr Biochem pmid:2634236
Sixt SU et al. Distinct proteasome subpopulations in the alveolar space of patients with the acute respiratory distress syndrome. 2012 Mediators Inflamm. pmid:22363101
D'Onofrio C et al. The influence of some metabolic inhibitors on in vitro phagocytizing macrophages. I. The behaviour of human macrophages. 1977 Med. Microbiol. Immunol. pmid:916975
Dhaneshwar S and Patil D Chondromodulating chimeric prodrugs of diacetylrhein: synthesis and evaluation in monoiodoacetate-induced hyperalgesia. 2013 Med Chem pmid:22920092
Barry AC et al. Protective effect of glucose on the anoxic myocardium of old and young mice. 1987 Mech. Ageing Dev. pmid:3695592
Veneziale CM and Swenson RP Gluconeogenesis in isolated hepatic parenchymal cells. VII. Effects of monobutyryl cyclic adenosine monophosphate on gluconeogenic intermediates, phosphofructokinase, and fructose diphosphatase. 1975 Mayo Clin. Proc. pmid:165334
Zakrzewska I et al. Low molecular organic inactivators in differentiating organ origin of alpha-amylase in humans. Part I. 1989 Oct-Dec Mater Med Pol pmid:2518736
Damon BM et al. The carnosine C-2 proton's chemical shift reports intracellular pH in oxidative and glycolytic muscle fibers. 2003 Magn Reson Med pmid:12541242
Stewart LC et al. Simultaneous measurement of both lipid and lactate in isolated rat hearts by 1H NMR spectroscopy. 1993 Magn Reson Med pmid:8139446
Battista N et al. Anandamide uptake by synaptosomes from human, mouse and rat brain: inhibition by glutamine and glutamate. 2002 Lipids Health Dis pmid:12617751
Gibson DD et al. GSH-dependent inhibition of lipid peroxidation: properties of a potent cytosolic system which protects cell membranes. 1985 Lipids pmid:4058268
Kawanishi T et al. Suppression of Na+ influx in ATP-depleted hepatocytes. 1995 Life Sci. pmid:7603308
Bartha E et al. Molecular form of human lymphocyte membrane-bound acetylcholinesterase. 1987 Life Sci. pmid:3657387
Yang NC et al. ATP depletion is an important factor in DHEA-induced growth inhibition and apoptosis in BV-2 cells. 2002 Life Sci. pmid:12148690
Turkelson CM Effects of ATP synthesis inhibitors, temperature, 8-bromo c-AMP, and calcium omission on release of corticotropin releasing factor from superfused rat hypothalami. 1988 Life Sci. pmid:3262804
Takaoka M et al. Activation of urinary inactive kallikrein by an extract from the rat kidney cortex. 1985 Life Sci. pmid:3897754
Kagawa S et al. Development and function of B cells in monolayer islet cells of 3-week-old rat. 1987 Life Sci. pmid:2444853
Smit V In vitro suppression of leukemia by alkylated interleukin-3. 1995 Leukemia pmid:7769858
Gill DS and Wickramasinghe SN Observations on the intracellular accumulation of methotrexate and 5-methyltetrahydrofolate in uninduced, dimethylsulphoxide-induced and 1,25-dihydroxyvitamin D3-induced HL60 cells, and blood-monocyte-derived human macrophages. 1988 Leuk. Res. pmid:2833665
Phelps PC et al. Cytosolic ionized calcium and bleb formation after acute cell injury of cultured rabbit renal tubule cells. 1989 Lab. Invest. pmid:2654473
Cazenave JP et al. Effects of sodium periodate on platelet functions. 1976 Lab. Invest. pmid:178961
Buja LM et al. Alterations of ultrastructure and elemental composition in cultured neonatal rat cardiac myocytes after metabolic inhibition with iodoacetic acid. 1985 Lab. Invest. pmid:2413276