Iodoacetic acid

Iodoacetic acid is a lipid of Fatty Acyls (FA) class. Iodoacetic acid is associated with abnormalities such as Photoreceptor degeneration and Post MI. The involved functions are known as Hypoxia, Glycolysis, Metabolic Inhibition, Oxidation and PTPS activity. Iodoacetic acid often locates in Extracellular, Muscle, Mitochondria, Cytoplasmic matrix and Tissue membrane. The associated genes with Iodoacetic acid are SLC33A1 gene, GTF2I gene, Mutant Proteins, TRIM33 gene and oxytocin, 1-desamino-(O-Et-Tyr)(2)-.

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Introduction

To understand associated biological information of Iodoacetic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Iodoacetic acid?

Iodoacetic acid is suspected in Photoreceptor degeneration, Post MI and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Iodoacetic acid

PubChem Associated disorders and diseases

What pathways are associated with Iodoacetic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Iodoacetic acid?

Related references are published most in these journals:

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What functions are associated with Iodoacetic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Iodoacetic acid?

There are no associated biomedical information in the current reference collection.

What genes are associated with Iodoacetic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Iodoacetic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Iodoacetic acid

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Authors Title Published Journal PubMed Link
Bazzocco S et al. Highly Expressed Genes in Rapidly Proliferating Tumor Cells as New Targets for Colorectal Cancer Treatment. 2015 Clin. Cancer Res. pmid:25944804
Procházka E et al. In Vitro Cytotoxicity and Adaptive Stress Responses to Selected Haloacetic Acid and Halobenzoquinone Water Disinfection Byproducts. 2015 Chem. Res. Toxicol. pmid:26327680
Bhattacharjee S et al. Site-Specific Zwitterionic Polymer Conjugates of a Protein Have Long Plasma Circulation. 2015 Chembiochem pmid:26481301
James AD et al. The Plasma Membrane Calcium Pump in Pancreatic Cancer Cells Exhibiting the Warburg Effect Relies on Glycolytic ATP. 2015 J. Biol. Chem. pmid:26294767
Rahman W et al. Electrophysiological evidence for voltage-gated calcium channel 2 (Cav2) modulation of mechano- and thermosensitive spinal neuronal responses in a rat model of osteoarthritis. 2015 Neuroscience pmid:26247695
Jeong YJ et al. Anti-Osteoarthritic Effects of the Litsea japonica Fruit in a Rat Model of Osteoarthritis Induced by Monosodium Iodoacetate. 2015 PLoS ONE pmid:26244981
Ogbonna AC et al. Development of monosodium acetate-induced osteoarthritis and inflammatory pain in ageing mice. 2015 Age (Dordr) pmid:25971876
Yassin NZ et al. Effect of a topical copper indomethacin gel on inflammatory parameters in a rat model of osteoarthritis. 2015 Drug Des Devel Ther pmid:25792809
Wang S and Kaltashov IA Identification of reduction-susceptible disulfide bonds in transferrin by differential alkylation using O(16)/O(18) labeled iodoacetic acid. 2015 J. Am. Soc. Mass Spectrom. pmid:25716754
Sagar DR et al. Dissecting the contribution of knee joint NGF to spinal nociceptive sensitization in a model of OA pain in the rat. 2015 Osteoarthr. Cartil. pmid:25623624
Liu Y et al. Activation of α7 nicotinic acetylcholine receptors prevents monosodium iodoacetate-induced osteoarthritis in rats. 2015 Cell. Physiol. Biochem. pmid:25613062
Barodka V et al. Nitroprusside inhibits calcium-induced impairment of red blood cell deformability. 2014 Transfusion pmid:23781865
Reinbold J et al. Quantitation of glutathione and its oxidation products in erythrocytes by multiple-label stable-isotope dilution. 2014 Anal. Biochem. pmid:24120409
van Buul GM et al. Mesenchymal stem cells reduce pain but not degenerative changes in a mono-iodoacetate rat model of osteoarthritis. 2014 J. Orthop. Res. pmid:24839120
Naveen SV et al. Histology, glycosaminoglycan level and cartilage stiffness in monoiodoacetate-induced osteoarthritis: comparative analysis with anterior cruciate ligament transection in rat model and human osteoarthritis. 2014 Int J Med Sci pmid:24396291
Tong P et al. Chondroprotective activity of a detoxicated traditional Chinese medicine (Fuzi) of Aconitum carmichaeli Debx against severe-stage osteoarthritis model induced by mono-iodoacetate. 2014 J Ethnopharmacol pmid:24315981
Brooke DG et al. Targeting the Warburg Effect in cancer; relationships for 2-arylpyridazinones as inhibitors of the key glycolytic enzyme 6-phosphofructo-2-kinase/2,6-bisphosphatase 3 (PFKFB3). 2014 Bioorg. Med. Chem. pmid:24398380
Sagar DR et al. Osteoprotegerin reduces the development of pain behaviour and joint pathology in a model of osteoarthritis. 2014 Ann. Rheum. Dis. pmid:23723320
Boudenot A et al. Effect of interval-training exercise on subchondral bone in a chemically-induced osteoarthritis model. 2014 Osteoarthr. Cartil. pmid:24928318
Lutas A et al. Metabolism regulates the spontaneous firing of substantia nigra pars reticulata neurons via KATP and nonselective cation channels. 2014 J. Neurosci. pmid:25471572