| MeSH term | MeSH ID | Detail |
|---|---|---|
| Arthritis, Experimental | D001169 | 24 associated lipids |
| Blindness | D001766 | 6 associated lipids |
| Blood Platelet Disorders | D001791 | 12 associated lipids |
| Brain Edema | D001929 | 20 associated lipids |
| Burns | D002056 | 34 associated lipids |
| Byssinosis | D002095 | 11 associated lipids |
| Brain Ischemia | D002545 | 89 associated lipids |
| Clonorchiasis | D003003 | 1 associated lipids |
| Coronary Disease | D003327 | 70 associated lipids |
| Epilepsy | D004827 | 35 associated lipids |
Iodoacetic acid
Iodoacetic acid is a lipid of Fatty Acyls (FA) class. Iodoacetic acid is associated with abnormalities such as Photoreceptor degeneration and Post MI. The involved functions are known as Hypoxia, Glycolysis, Metabolic Inhibition, Oxidation and PTPS activity. Iodoacetic acid often locates in Extracellular, Muscle, Mitochondria, Cytoplasmic matrix and Tissue membrane. The associated genes with Iodoacetic acid are SLC33A1 gene, GTF2I gene, Mutant Proteins, TRIM33 gene and oxytocin, 1-desamino-(O-Et-Tyr)(2)-.
Cross Reference
Introduction
To understand associated biological information of Iodoacetic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Iodoacetic acid?
Iodoacetic acid is suspected in Photoreceptor degeneration, Post MI and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Iodoacetic acid
PubChem Associated disorders and diseases
What pathways are associated with Iodoacetic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Iodoacetic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Iodoacetic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Iodoacetic acid?
There are no associated biomedical information in the current reference collection.
What genes are associated with Iodoacetic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Iodoacetic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Iodoacetic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Wei X et al. | Drinking water disinfection byproduct iodoacetic acid induces tumorigenic transformation of NIH3T3 cells. | 2013 | Environ. Sci. Technol. | pmid:23641915 |
| Nan Y et al. | Functional evaluation of iodoacetic acid induced photoreceptor degeneration in the cat. | 2013 | Sci China Life Sci | pmid:23657794 |
| More AS et al. | Effect of iNOS inhibitor S-methylisothiourea in monosodium iodoacetate-induced osteoathritic pain: implication for osteoarthritis therapy. | 2013 | Pharmacol. Biochem. Behav. | pmid:23287799 |
| La Porta C et al. | Role of CB1 and CB2 cannabinoid receptors in the development of joint pain induced by monosodium iodoacetate. | 2013 | Pain | pmid:23199705 |
| Song M et al. | Monitoring of deiodinase deficiency based on transcriptomic responses in SH-SY5Y cells. | 2013 | Arch. Toxicol. | pmid:23397585 |
| Moon SJ et al. | Augmented chondroprotective effect of coadministration of celecoxib and rebamipide in the monosodium iodoacetate rat model of osteoarthritis. | 2013 | Arch. Pharm. Res. | pmid:23338062 |
| Ogbonna AC et al. | Pain-like behaviour and spinal changes in the monosodium iodoacetate model of osteoarthritis in C57Bl/6 mice. | 2013 | Eur J Pain | pmid:23169679 |
| Ye T et al. | Formation of iodinated disinfection by-products during oxidation of iodide-containing waters with chlorine dioxide. | 2013 | Water Res. | pmid:23561492 |
| Thote T et al. | Localized 3D analysis of cartilage composition and morphology in small animal models of joint degeneration. | 2013 | Osteoarthr. Cartil. | pmid:23747340 |
| Kelly S et al. | Spinal nociceptive reflexes are sensitized in the monosodium iodoacetate model of osteoarthritis pain in the rat. | 2013 | Osteoarthr. Cartil. | pmid:23973147 |
| Mapp PI et al. | Differences in structural and pain phenotypes in the sodium monoiodoacetate and meniscal transection models of osteoarthritis. | 2013 | Osteoarthr. Cartil. | pmid:23973148 |
| Lee J et al. | Coenzyme Q10 ameliorates pain and cartilage degradation in a rat model of osteoarthritis by regulating nitric oxide and inflammatory cytokines. | 2013 | PLoS ONE | pmid:23894457 |
| Wang XD et al. | Estrogen aggravates iodoacetate-induced temporomandibular joint osteoarthritis. | 2013 | J. Dent. Res. | pmid:23934157 |
| Shao H et al. | Intra-articular injection of xanthan gum reduces pain and cartilage damage in a rat osteoarthritis model. | 2013 | Carbohydr Polym | pmid:23399228 |
| Cialdai C et al. | Comparison between oral and intra-articular antinociceptive effect of dexketoprofen and tramadol combination in monosodium iodoacetate-induced osteoarthritis in rats. | 2013 | Eur. J. Pharmacol. | pmid:23891968 |
| Escobar-Hoyos LF et al. | Genotoxic and clastogenic effects of monohaloacetic acid drinking water disinfection by-products in primary human lymphocytes. | 2013 | Water Res. | pmid:23602619 |
| Pals J et al. | Human cell toxicogenomic analysis linking reactive oxygen species to the toxicity of monohaloacetic acid drinking water disinfection byproducts. | 2013 | Environ. Sci. Technol. | pmid:24050308 |
| Dhaneshwar S and Patil D | Chondromodulating chimeric prodrugs of diacetylrhein: synthesis and evaluation in monoiodoacetate-induced hyperalgesia. | 2013 | Med Chem | pmid:22920092 |
| Liu X et al. | An optimized analytical method for the simultaneous detection of iodoform, iodoacetic acid, and other trihalomethanes and haloacetic acids in drinking water. | 2013 | PLoS ONE | pmid:23613747 |
| Thakur M et al. | Characterisation of a peripheral neuropathic component of the rat monoiodoacetate model of osteoarthritis. | 2012 | PLoS ONE | pmid:22470467 |