Iodoacetic acid

Iodoacetic acid is a lipid of Fatty Acyls (FA) class. Iodoacetic acid is associated with abnormalities such as Photoreceptor degeneration and Post MI. The involved functions are known as Hypoxia, Glycolysis, Metabolic Inhibition, Oxidation and PTPS activity. Iodoacetic acid often locates in Extracellular, Muscle, Mitochondria, Cytoplasmic matrix and Tissue membrane. The associated genes with Iodoacetic acid are SLC33A1 gene, GTF2I gene, Mutant Proteins, TRIM33 gene and oxytocin, 1-desamino-(O-Et-Tyr)(2)-.

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Introduction

To understand associated biological information of Iodoacetic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Iodoacetic acid?

Iodoacetic acid is suspected in Photoreceptor degeneration, Post MI and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Iodoacetic acid

MeSH term MeSH ID Detail
Osteoarthritis, Spine D055013 2 associated lipids
Osteophyte D054850 2 associated lipids
Monckeberg Medial Calcific Sclerosis D050380 1 associated lipids
Vitamin B 6 Deficiency D026681 10 associated lipids
Stroke D020521 32 associated lipids
Osteoarthritis, Knee D020370 13 associated lipids
Thrombophilia D019851 6 associated lipids
Arthralgia D018771 8 associated lipids
Hypertrophy, Left Ventricular D017379 12 associated lipids
Reperfusion Injury D015427 65 associated lipids
Per page 10 20 50 100 | Total 54

PubChem Associated disorders and diseases

What pathways are associated with Iodoacetic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Iodoacetic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Iodoacetic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Iodoacetic acid?

There are no associated biomedical information in the current reference collection.

What genes are associated with Iodoacetic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Iodoacetic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Iodoacetic acid

Download all related citations
Per page 10 20 50 100 | Total 2490
Authors Title Published Journal PubMed Link
Bar-Yehuda S et al. Induction of an antiinflammatory effect and prevention of cartilage damage in rat knee osteoarthritis by CF101 treatment. 2009 Arthritis Rheum. pmid:19790055
Tolonen AC et al. Targeted gene inactivation in Clostridium phytofermentans shows that cellulose degradation requires the family 9 hydrolase Cphy3367. 2009 Mol. Microbiol. pmid:19775243
Castillo-Romero A et al. Participation of actin on Giardia lamblia growth and encystation. 2009 PLoS ONE pmid:19774081
Santos-Rosa H et al. Histone H3 tail clipping regulates gene expression. 2009 Nat. Struct. Mol. Biol. pmid:19079264
Chumsae C et al. Identification and localization of unpaired cysteine residues in monoclonal antibodies by fluorescence labeling and mass spectrometry. 2009 Anal. Chem. pmid:19572546
Baragi VM et al. A new class of potent matrix metalloproteinase 13 inhibitors for potential treatment of osteoarthritis: Evidence of histologic and clinical efficacy without musculoskeletal toxicity in rat models. 2009 Arthritis Rheum. pmid:19565489
Suna H et al. Dysideamine, a new sesquiterpene aminoquinone, protects hippocampal neuronal cells against iodoacetic acid-induced cell death. 2009 Bioorg. Med. Chem. pmid:19414266
Huisamen B et al. Signalling pathways activated by glucagon-like peptide-1 (7-36) amide in the rat heart and their role in protection against ischaemia. 2008 Mar-Apr Cardiovasc J Afr pmid:18516352
Liang L et al. Long-term cellular and regional specificity of the photoreceptor toxin, iodoacetic acid (IAA), in the rabbit retina. 2008 Mar-Apr Vis. Neurosci. pmid:18442439
John SA et al. Dynamic modulation of intracellular glucose imaged in single cells using a FRET-based glucose nanosensor. 2008 Pflugers Arch. pmid:18071748
Brown KK et al. P38 MAP kinase inhibitors as potential therapeutics for the treatment of joint degeneration and pain associated with osteoarthritis. 2008 J Inflamm (Lond) pmid:19055838
Bourdineaud JP et al. Feeding mice with diets containing mercury-contaminated fish flesh from French Guiana: a model for the mercurial intoxication of the Wayana Amerindians. 2008 Environ Health pmid:18959803
Srivastava OP et al. Isolation and characterization of betaA3-crystallin associated proteinase from alpha-crystallin fraction of human lenses. 2008 Mol. Vis. pmid:18949065
Samra ZQ and Athar MA Cloning, sequence, expression and characterization of human beta-mannosidase. 2008 Acta Biochim. Pol. pmid:18800177
Lushchak V et al. Pdr12p-dependent and -independent fluorescein extrusion from baker's yeast cells. 2008 Acta Biochim. Pol. pmid:18800175
Le Bihan-Duval E et al. Chicken meat quality: genetic variability and relationship with growth and muscle characteristics. 2008 BMC Genet. pmid:18706119
Thal DR et al. Tracing of temporo-entorhinal connections in the human brain: cognitively impaired argyrophilic grain disease cases show dendritic alterations but no axonal disconnection of temporo-entorhinal association neurons. 2008 Acta Neuropathol. pmid:18075746
Wurm A et al. Glial cell-derived glutamate mediates autocrine cell volume regulation in the retina: activation by VEGF. 2008 J. Neurochem. pmid:17953668
Yang JH et al. Glycolytic oscillations in isolated rabbit ventricular myocytes. 2008 J. Biol. Chem. pmid:18948270
Lau BP and Becalski A Determination of iodoacetic acid using liquid chromatography/electrospray tandem mass spectrometry. 2008 Rapid Commun. Mass Spectrom. pmid:18470871