Iodoacetic acid

Iodoacetic acid is a lipid of Fatty Acyls (FA) class. Iodoacetic acid is associated with abnormalities such as Photoreceptor degeneration and Post MI. The involved functions are known as Hypoxia, Glycolysis, Metabolic Inhibition, Oxidation and PTPS activity. Iodoacetic acid often locates in Extracellular, Muscle, Mitochondria, Cytoplasmic matrix and Tissue membrane. The associated genes with Iodoacetic acid are SLC33A1 gene, GTF2I gene, Mutant Proteins, TRIM33 gene and oxytocin, 1-desamino-(O-Et-Tyr)(2)-.

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Introduction

To understand associated biological information of Iodoacetic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Iodoacetic acid?

Iodoacetic acid is suspected in Photoreceptor degeneration, Post MI and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Iodoacetic acid

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Pain D010146 64 associated lipids
Lung Neoplasms D008175 171 associated lipids
Wounds and Injuries D014947 20 associated lipids
Burns D002056 34 associated lipids
Inflammation D007249 119 associated lipids
Reperfusion Injury D015427 65 associated lipids
Mammary Neoplasms, Experimental D008325 67 associated lipids
Sarcoma 180 D012510 21 associated lipids
Arthritis, Experimental D001169 24 associated lipids
Osteoarthritis D010003 4 associated lipids
Coronary Disease D003327 70 associated lipids
Leukemia, Erythroblastic, Acute D004915 41 associated lipids
Glioma D005910 112 associated lipids
Liver Neoplasms, Experimental D008114 46 associated lipids
Lymphoma D008223 18 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Osteoarthritis, Knee D020370 13 associated lipids
Brain Edema D001929 20 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Iodoacetic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Iodoacetic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Iodoacetic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Iodoacetic acid?

There are no associated biomedical information in the current reference collection.

What genes are associated with Iodoacetic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Iodoacetic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Iodoacetic acid

Download all related citations
Per page 10 20 50 100 | Total 2490
Authors Title Published Journal PubMed Link
Gallis JL et al. Resveratrol plus ethanol counteract the ethanol-induced impairment of energy metabolism: ³¹P NMR study of ATP and sn-glycerol-3-phosphate on isolated and perfused rat liver. 2012 Pharmacol. Res. pmid:22227530
Wang YC et al. Intracellular Na(+) and metabolic modulation of Na/K pump and excitability in the rat suprachiasmatic nucleus neurons. 2012 J. Neurophysiol. pmid:22773774
Cardador MJ and Gallego M Development of a method for the quantitation of chloro-, bromo-, and iodoacetic acids in alcoholic beverages. 2012 J. Agric. Food Chem. pmid:22225467
Wang XD et al. Progression of cartilage degradation, bone resorption and pain in rat temporomandibular joint osteoarthritis induced by injection of iodoacetate. 2012 PLoS ONE pmid:22984604
Lee JH et al. Alteration patterns of trabecular bone microarchitectural characteristics induced by osteoarthritis over time. 2012 Clin Interv Aging pmid:22956865
Moon SJ et al. Rebamipide attenuates pain severity and cartilage degeneration in a rat model of osteoarthritis by downregulating oxidative damage and catabolic activity in chondrocytes. 2012 Osteoarthr. Cartil. pmid:22890185
Vincent A et al. parkin-induced defects in neurophysiology and locomotion are generated by metabolic dysfunction and not oxidative stress. 2012 Hum. Mol. Genet. pmid:22215442
Ferreira-Gomes J et al. Dose-dependent expression of neuronal injury markers during experimental osteoarthritis induced by monoiodoacetate in the rat. 2012 Mol Pain pmid:22769424
Noel JM et al. Iodoacetic acid, but not sodium iodate, creates an inducible swine model of photoreceptor damage. 2012 Exp. Eye Res. pmid:22251455
Hardes K et al. Design, synthesis, and characterization of chromogenic substrates of coagulation factor XIIIa. 2012 Anal. Biochem. pmid:22683584
Rao Y et al. Mapping of sulfur metabolic pathway by LC Orbitrap mass spectrometry. 2012 Anal. Chim. Acta pmid:22405311
More AS et al. Effect of iNOS inhibitor S-methylisothiourea in monosodium iodoacetate-induced osteoathritic pain: implication for osteoarthritis therapy. 2013 Pharmacol. Biochem. Behav. pmid:23287799
La Porta C et al. Role of CB1 and CB2 cannabinoid receptors in the development of joint pain induced by monosodium iodoacetate. 2013 Pain pmid:23199705
Song M et al. Monitoring of deiodinase deficiency based on transcriptomic responses in SH-SY5Y cells. 2013 Arch. Toxicol. pmid:23397585
Moon SJ et al. Augmented chondroprotective effect of coadministration of celecoxib and rebamipide in the monosodium iodoacetate rat model of osteoarthritis. 2013 Arch. Pharm. Res. pmid:23338062
Ogbonna AC et al. Pain-like behaviour and spinal changes in the monosodium iodoacetate model of osteoarthritis in C57Bl/6 mice. 2013 Eur J Pain pmid:23169679
Ye T et al. Formation of iodinated disinfection by-products during oxidation of iodide-containing waters with chlorine dioxide. 2013 Water Res. pmid:23561492
Thote T et al. Localized 3D analysis of cartilage composition and morphology in small animal models of joint degeneration. 2013 Osteoarthr. Cartil. pmid:23747340
Kelly S et al. Spinal nociceptive reflexes are sensitized in the monosodium iodoacetate model of osteoarthritis pain in the rat. 2013 Osteoarthr. Cartil. pmid:23973147
Pals J et al. Human cell toxicogenomic analysis linking reactive oxygen species to the toxicity of monohaloacetic acid drinking water disinfection byproducts. 2013 Environ. Sci. Technol. pmid:24050308