Iodoacetic acid is a lipid of Fatty Acyls (FA) class. Iodoacetic acid is associated with abnormalities such as Photoreceptor degeneration and Post MI. The involved functions are known as Hypoxia, Glycolysis, Metabolic Inhibition, Oxidation and PTPS activity. Iodoacetic acid often locates in Extracellular, Muscle, Mitochondria, Cytoplasmic matrix and Tissue membrane. The associated genes with Iodoacetic acid are SLC33A1 gene, GTF2I gene, Mutant Proteins, TRIM33 gene and oxytocin, 1-desamino-(O-Et-Tyr)(2)-.
To understand associated biological information of Iodoacetic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Iodoacetic acid is suspected in Photoreceptor degeneration, Post MI and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with Iodoacetic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Hudman JF and Glenn AR | Selenite uptake and incorporation by Selenomonas ruminantium. | 1984 | Arch. Microbiol. | pmid:6442129 |
Engel P et al. | Reversible interconversion of the functional state of the gene regulator FNR from Escherichia coli in vivo by O2 and iron availability. | 1991 | Arch. Microbiol. | pmid:1785953 |
Ditzelmüller G et al. | Nucleotide pools of growing, synchronized and stressed cultures of Saccharomyces cerevisiae. | 1983 | Arch. Microbiol. | pmid:6354131 |
Tabillion R and Kaltwasser H | [Energy-dependent 63Ni-uptake by Alcaligenes eutrophus strains H1 and H16 (author's transl)]. | 1977 | Arch. Microbiol. | pmid:889383 |
Neeff J and Mecke D | In vivo and in vitro studies on the glucose dependent inactivation of yeast cytoplasmic malate dehydrogenase. | 1977 | Arch. Microbiol. | pmid:337921 |
Campochiaro PA and Blaydes SH | Photocoagulation does not ablate angiogenic markers in rabbit retina. | 1988 | Arch. Ophthalmol. | pmid:2451908 |
Kawase N et al. | Collagenolytic activity in sonic extracts of Tannerella forsythia. | 2010 | Arch. Oral Biol. | pmid:20619781 |
Chung Y and Cho H | Preparation of highly water soluble tacrolimus derivatives: poly(ethylene glycol) esters as potential prodrugs. | 2004 | Arch. Pharm. Res. | pmid:15460452 |
Moon SJ et al. | Augmented chondroprotective effect of coadministration of celecoxib and rebamipide in the monosodium iodoacetate rat model of osteoarthritis. | 2013 | Arch. Pharm. Res. | pmid:23338062 |
Song M et al. | Monitoring of deiodinase deficiency based on transcriptomic responses in SH-SY5Y cells. | 2013 | Arch. Toxicol. | pmid:23397585 |
Heilmaier HE and Summer KH | Metallothionein content and zinc status in various tissues of rats treated with iodoacetic acid and zinc. | 1985 | Arch. Toxicol. | pmid:3994507 |
Lock EA et al. | Transport of N-acetyl-S-pentachloro-1,3-butadienylcysteine by rat renal cortex. | 1986 | Arch. Toxicol. | pmid:3741137 |
Smith LL | Young Scientists Award lecture 1981: The identification of an accumulation system for diamines and polyamines into the lung and its relevance to paraquat toxicity. | 1982 | Arch. Toxicol. Suppl. | pmid:6954885 |
Peyfoon E et al. | The S-layer glycoprotein of the crenarchaeote Sulfolobus acidocaldarius is glycosylated at multiple sites with chitobiose-linked N-glycans. | 2010 | Archaea | pmid:20936123 |
Van Tol A et al. | Net mass transfer of cholesteryl esters from low density lipoproteins to high density lipoproteins in plasma from normolipidemic subjects. | 1991 Jan-Feb | Arterioscler. Thromb. | pmid:1988004 |
Chang YS et al. | Shear-induced increase in hydraulic conductivity in endothelial cells is mediated by a nitric oxide-dependent mechanism. | 2000 | Arterioscler. Thromb. Vasc. Biol. | pmid:10634798 |
Wilson CG et al. | Aggrecanolysis and in vitro matrix degradation in the immature bovine meniscus: mechanisms and functional implications. | 2009 | Arthritis Res. Ther. | pmid:19919704 |
Krzeski P et al. | Development of musculoskeletal toxicity without clear benefit after administration of PG-116800, a matrix metalloproteinase inhibitor, to patients with knee osteoarthritis: a randomized, 12-month, double-blind, placebo-controlled study. | 2007 | Arthritis Res. Ther. | pmid:17958901 |
Koufany M et al. | Anti-inflammatory effect of antidiabetic thiazolidinediones prevents bone resorption rather than cartilage changes in experimental polyarthritis. | 2008 | Arthritis Res. Ther. | pmid:18199331 |
Dray A and Read SJ | Arthritis and pain. Future targets to control osteoarthritis pain. | 2007 | Arthritis Res. Ther. | pmid:17561993 |
Beyreuther B et al. | Antinociceptive efficacy of lacosamide in the monosodium iodoacetate rat model for osteoarthritis pain. | 2007 | Arthritis Res. Ther. | pmid:17284318 |
Appleton CT et al. | Forced mobilization accelerates pathogenesis: characterization of a preclinical surgical model of osteoarthritis. | 2007 | Arthritis Res. Ther. | pmid:17284317 |
Keravala A et al. | Human, viral or mutant human IL-10 expressed after local adenovirus-mediated gene transfer are equally effective in ameliorating disease pathology in a rabbit knee model of antigen-induced arthritis. | 2006 | Arthritis Res. Ther. | pmid:16704745 |
Mastbergen SC et al. | Differential direct effects of cyclo-oxygenase-1/2 inhibition on proteoglycan turnover of human osteoarthritic cartilage: an in vitro study. | 2006 | Arthritis Res. Ther. | pmid:16356188 |
Mohan G et al. | Application of in vivo micro-computed tomography in the temporal characterisation of subchondral bone architecture in a rat model of low-dose monosodium iodoacetate-induced osteoarthritis. | 2011 | Arthritis Res. Ther. | pmid:22185204 |
Otis C et al. | Concurrent validity of different functional and neuroproteomic pain assessment methods in the rat osteoarthritis monosodium iodoacetate (MIA) model. | 2016 | Arthritis Res. Ther. | pmid:27338815 |
Kim JS et al. | The rat intervertebral disk degeneration pain model: relationships between biological and structural alterations and pain. | 2011 | Arthritis Res. Ther. | pmid:21996269 |
Moreau M et al. | Tiludronate treatment improves structural changes and symptoms of osteoarthritis in the canine anterior cruciate ligament model. | 2011 | Arthritis Res. Ther. | pmid:21693018 |
Uchii M et al. | Role of fibroblast growth factor 8 (FGF8) in animal models of osteoarthritis. | 2008 | Arthritis Res. Ther. | pmid:18699993 |
Catterall JB et al. | Changes in serum and synovial fluid biomarkers after acute injury (NCT00332254). | 2010 | Arthritis Res. Ther. | pmid:21194441 |
Schuelert N and McDougall JJ | Involvement of Nav 1.8 sodium ion channels in the transduction of mechanical pain in a rodent model of osteoarthritis. | 2012 | Arthritis Res. Ther. | pmid:22225591 |
Sniekers YH et al. | Oestrogen is important for maintenance of cartilage and subchondral bone in a murine model of knee osteoarthritis. | 2010 | Arthritis Res. Ther. | pmid:20923566 |
Ferreira-Gomes J et al. | Phenotypic alterations of neurons that innervate osteoarthritic joints in rats. | 2010 | Arthritis Rheum. | pmid:20722015 |
Im HJ et al. | Alteration of sensory neurons and spinal response to an experimental osteoarthritis pain model. | 2010 | Arthritis Rheum. | pmid:20556813 |
Bar-Yehuda S et al. | Induction of an antiinflammatory effect and prevention of cartilage damage in rat knee osteoarthritis by CF101 treatment. | 2009 | Arthritis Rheum. | pmid:19790055 |
Williams JM and Brandt KD | Immobilization ameliorates chemically-induced articular cartilage damage. | 1984 | Arthritis Rheum. | pmid:6696774 |
Sagar DR et al. | Tonic modulation of spinal hyperexcitability by the endocannabinoid receptor system in a rat model of osteoarthritis pain. | 2010 | Arthritis Rheum. | pmid:20722027 |
Schuelert N and McDougall JJ | Cannabinoid-mediated antinociception is enhanced in rat osteoarthritic knees. | 2008 | Arthritis Rheum. | pmid:18163511 |
Williams JM and Brandt KD | Triamcinolone hexacetonide protects against fibrillation and osteophyte formation following chemically induced articular cartilage damage. | 1985 | Arthritis Rheum. | pmid:4063001 |
Nam J et al. | Transcriptome-wide gene regulation by gentle treadmill walking during the progression of monoiodoacetate-induced arthritis. | 2011 | Arthritis Rheum. | pmid:21400474 |
Baragi VM et al. | A new class of potent matrix metalloproteinase 13 inhibitors for potential treatment of osteoarthritis: Evidence of histologic and clinical efficacy without musculoskeletal toxicity in rat models. | 2009 | Arthritis Rheum. | pmid:19565489 |
Xie L et al. | Quantitative imaging of cartilage and bone morphology, reactive oxygen species, and vascularization in a rodent model of osteoarthritis. | 2012 | Arthritis Rheum. | pmid:22231023 |
Kim JS et al. | Characterization of a new animal model for evaluation and treatment of back pain due to lumbar facet joint osteoarthritis. | 2011 | Arthritis Rheum. | pmid:21953085 |
Simchowitz L et al. | Chemotactic factor-induced generation of superoxide radicals by human neutrophils: effect of metabolic inhibitors and antiinflammatory drugs. | 1979 | Arthritis Rheum. | pmid:222300 |
Piscaer TM et al. | Imaging of activated macrophages in experimental osteoarthritis using folate-targeted animal single-photon-emission computed tomography/computed tomography. | 2011 | Arthritis Rheum. | pmid:21437875 |
KOHLER V and BAUER R | [Reticulocytosis of the circulating blood provoked by monoiodoacetic acid as a symptom of the adaptation syndrome]. | 1951 | Arztl Wochensch | pmid:14856887 |
Yang Y and Balcarcel RR | 96-well plate assay for sublethal metabolic activity. | 2004 | Assay Drug Dev Technol | pmid:15357916 |
Blaes N and Covacho C | Transformed rat arterial smooth muscle cells induce platelet aggregation. | 1994 | Atherosclerosis | pmid:7848366 |
Webster DM et al. | Amino acid sequences containing cysteine or cystine residues in ovalbumin from eggs of the quail Coturnix coturnix japonica. | 1981 | Aust. J. Biol. Sci. | pmid:7340765 |
Webster DM and Thompson EO | Carboxymethylation of thiol groups in ovalbumin: implications for proteins that contain both thiol and disulfide groups. | 1982 | Aust. J. Biol. Sci. | pmid:7126053 |
Sammut EB and Kannegieter NJ | Use of sodium monoiodoacetate to fuse the distal hock joints in horses. | 1995 | Aust. Vet. J. | pmid:8787522 |
Whitton C | Chemical arthrodesis of the distal tarsal joints using sodium monoiodoacetate in 104 horses. | 2004 | Aust. Vet. J. | pmid:15181929 |
Thomas JA and Park EM | Oxy radical-initiated protein S-thiolation and enzymic dethiolation. | 1988 | Basic Life Sci. | pmid:3250494 |
Lipasti JA et al. | The relationship between ischemic contracture and no-reflow phenomenon in isolated rat heart. | 1982 Jul-Aug | Basic Res. Cardiol. | pmid:7150210 |
Regling G et al. | [Monoiodoacetic acid-induced arthropathy of the rabbit knee--a contribution to the pathogenesis of arthrosis]. | 1989 | Beitr Orthop Traumatol | pmid:2751625 |
Laiho KU and Trump BF | Mitochondrial changes, ion and water shifts in the cellular injury of ehrlich ascites tumor cells. | 1975 | Beitr Pathol | pmid:170904 |
Talwar HS et al. | Sodium glycolate absorption in rat intestine. | 1984 | Biochem Med | pmid:6477536 |
Chew A et al. | Mutations in a putative zinc-binding domain inactivate the mitochondrial intermediate peptidase. | 1996 | Biochem. Biophys. Res. Commun. | pmid:8831696 |
Brodie AE and Reed DJ | Reversible oxidation of glyceraldehyde 3-phosphate dehydrogenase thiols in human lung carcinoma cells by hydrogen peroxide. | 1987 | Biochem. Biophys. Res. Commun. | pmid:3675570 |
Canfield LM | Vitamin K-dependent oxygenase/carboxylase; differential inactivation by sulfhydryl reagents. | 1987 | Biochem. Biophys. Res. Commun. | pmid:3675572 |
Yasuhara T and Ohashi A | New chelator-sensitive proteases in matrix of yeast mitochondria. | 1987 | Biochem. Biophys. Res. Commun. | pmid:3555485 |
Villalba JM et al. | Thiol groups are involved in NADH-ascorbate free radical reductase activity of rat liver plasma membrane. | 1993 | Biochem. Biophys. Res. Commun. | pmid:8484777 |
Ding PZ | An investigation of cysteine mutants on the cytoplasmic loop X/XI in the melibiose transporter of Escherichia coli by using thiol reagents: implication of structural conservation of charged residues. | 2003 | Biochem. Biophys. Res. Commun. | pmid:12878191 |
Nyberg F et al. | Endopeptidase in human cerebrospinal fluid which cleaves proenkephalin B opioid peptides at consecutive basic amino acids. | 1985 | Biochem. Biophys. Res. Commun. | pmid:2864927 |
Advani S and Roy KB | Properties and secondary structure analysis of BanI endonuclease: identification of putative active site. | 2000 | Biochem. Biophys. Res. Commun. | pmid:11112410 |
Haniu M et al. | Heme binding and substrate-protected cysteine residues in P-450cam. | 1983 | Biochem. Biophys. Res. Commun. | pmid:6639664 |
Fisher JM et al. | Evidence for a membrane sulfhydryl associated with resistance to melphalan in a murine L1210 leukemia line. | 1983 | Biochem. Biophys. Res. Commun. | pmid:6667269 |
Ikeda U et al. | Identification of two new calcium dependent hydrolases in the human heart. | 1986 | Biochem. Biophys. Res. Commun. | pmid:3010997 |
Pasero L et al. | Localization of the two free thiol groups in the porcine pancreatic alpha-amylase I sequence. | 1983 | Biochem. Biophys. Res. Commun. | pmid:6188459 |
Tomlinson G and Kinsch EM | S-mercuric-N-dansyl-cysteine labels the free sulfhydryl groups of human serum cholinesterase. | 1989 | Biochem. Biophys. Res. Commun. | pmid:2916998 |
Harrison DC et al. | A pH-dependent phospholipase A2 contributes to loss of plasma membrane integrity during chemical hypoxia in rat hepatocytes. | 1991 | Biochem. Biophys. Res. Commun. | pmid:1899571 |
Jha S et al. | Covalent modification of cysteine 193 impairs ATPase function of nucleotide-binding domain of a Candida drug efflux pump. | 2003 | Biochem. Biophys. Res. Commun. | pmid:14550284 |
Seya T and Nagasawa S | Isolation of an iC3b forming enzyme from peritoneal polymorphonuclear leukocytes of guinea pigs. | 1983 | Biochem. Biophys. Res. Commun. | pmid:6229252 |
Güther T et al. | Regulation of intracellular magnesium by Mg2+ efflux. | 1984 | Biochem. Biophys. Res. Commun. | pmid:6422934 |
Kuzminskaya EV et al. | Rabbit muscle D-glyceraldehyde-3-phosphate dehydrogenase: half-of-the-sites reactivity of the enzyme modified at arginine residues. | 1992 | Biochem. Biophys. Res. Commun. | pmid:1530616 |
Kirley JW and Day RA | Irreversible inhibition of carbonic anhydrase by the carbon dioxide analog cyanogen. | 1985 | Biochem. Biophys. Res. Commun. | pmid:3918532 |
Holtzer ME et al. | The effect of sulfhydryl blocking groups on the thermal unfolding of alpha alpha tropomyosin coiled coils. | 1990 | Biochem. Biophys. Res. Commun. | pmid:2306243 |
Kyprianou N and Isaacs JT | "Thymineless" death in androgen-independent prostatic cancer cells. | 1989 | Biochem. Biophys. Res. Commun. | pmid:2531584 |
Harrsch PB et al. | Amino acid sequence similarity between spinach chloroplast and mammalian gluconeogenic fructose-1,6-bisphosphatase. | 1985 | Biochem. Biophys. Res. Commun. | pmid:3002349 |
Peltier JB and Rossignol M | Auxin-induced differential sensitivity of the H+-ATPase in plasma membrane subfractions from tobacco cells. | 1996 | Biochem. Biophys. Res. Commun. | pmid:8605015 |
Stan-Lotter H and Bragg PD | Electrophoretic determination of sulfhydryl groups and its application to complex protein samples, in vitro protein synthesis mixtures, and cross-linked proteins. | 1986 | Biochem. Cell Biol. | pmid:3755048 |
Lima-Catelani AR et al. | Variation of genetic expression during development, revealed by esterase patterns in Aedes aegypti (Diptera, Culicidae). | 2004 | Biochem. Genet. | pmid:15168721 |
Okochi VI et al. | Studies on the mechanism of adenosine transport in Trypanosoma vivax. | 1983 | Biochem. Int. | pmid:6679318 |
Goswami A and Rosenberg IN | Reactive thiols in type II iodothyronine 5'-deiodinases: inactivation by iodoacetate. | 1989 | Biochem. Int. | pmid:2818601 |
Berni R et al. | New crystalline derivatives of bovine liver rhodanese. | 1986 | Biochem. Int. | pmid:3460592 |
Hawkins HC and Freedman RB | The reactivities and ionization properties of the active-site dithiol groups of mammalian protein disulphide-isomerase. | 1991 | Biochem. J. | pmid:2025220 |
Hawkins HC et al. | Redox properties and cross-linking of the dithiol/disulphide active sites of mammalian protein disulphide-isomerase. | 1991 | Biochem. J. | pmid:2025221 |
Carne T et al. | The binding and catalytic activities of forms of ligandin after modification of its thiol groups. | 1979 | Biochem. J. | pmid:435243 |
Bridgen J | The reactivity and function of thiol groups in trout actin. | 1972 | Biochem. J. | pmid:4672661 |
Liao TH and Hsieh JC | Hydrolysis of p-nitrophenyl phenylphosphonate catalysed by bovine pancreatic deoxyribonuclease. | 1988 | Biochem. J. | pmid:3214425 |
Luaces AL and Barrett AJ | Affinity purification and biochemical characterization of histolysin, the major cysteine proteinase of Entamoeba histolytica. | 1988 | Biochem. J. | pmid:2898937 |
Clark MG et al. | Catecholamines and Ca2+ mediate an increase in activity and reactive thiols of rat heart phosphofructokinase. | 1987 | Biochem. J. | pmid:2954541 |
RodrÃguez-Aparicio LB et al. | Uptake of N-acetylneuraminic acid by Escherichia coli K-235. Biochemical characterization of the transport system. | 1987 | Biochem. J. | pmid:2825630 |
Csoma C and Polgár L | Proteinase from germinating bean cotyledons. Evidence for involvement of a thiol group in catalysis. | 1984 | Biochem. J. | pmid:6385962 |
Barrett AJ et al. | L-trans-Epoxysuccinyl-leucylamido(4-guanidino)butane (E-64) and its analogues as inhibitors of cysteine proteinases including cathepsins B, H and L. | 1982 | Biochem. J. | pmid:7044372 |
Ewart RB and Taylor KW | The regulation of growth hormone secretion from the isolated rat anterior pituitary in vitro. The role of adenosine 3':5'-cyclic monophosphate. | 1971 | Biochem. J. | pmid:4331962 |
Podoler H and Applebaum SW | The -amylase of the Beetle Callosobruchus chinensis. Properties. | 1971 | Biochem. J. | pmid:5000646 |
Franzen B et al. | Amino acid sequence of the tryptic peptide containing the catalytic-site thiol group of bovine liver uridine diphosphate glucose dehydrogenase. | 1981 | Biochem. J. | pmid:6896145 |
Morgan MS et al. | Participation of cellular thiol/disulphide groups in the uptake, degradation and bioactivity of insulin in primary cultures of rat hepatocytes. | 1985 | Biochem. J. | pmid:3883990 |
Schwartz W and Bird JW | Degradation of myofibrillar proteins by cathepsins B and D. | 1977 | Biochem. J. | pmid:23766 |