Iodoacetic acid is a lipid of Fatty Acyls (FA) class. Iodoacetic acid is associated with abnormalities such as Photoreceptor degeneration and Post MI. The involved functions are known as Hypoxia, Glycolysis, Metabolic Inhibition, Oxidation and PTPS activity. Iodoacetic acid often locates in Extracellular, Muscle, Mitochondria, Cytoplasmic matrix and Tissue membrane. The associated genes with Iodoacetic acid are SLC33A1 gene, GTF2I gene, Mutant Proteins, TRIM33 gene and oxytocin, 1-desamino-(O-Et-Tyr)(2)-.
To understand associated biological information of Iodoacetic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Iodoacetic acid is suspected in Photoreceptor degeneration, Post MI and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Iodoacetic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Barry WH et al. | Effects of graded hypoxia on contraction of cultured chick embryo ventricular cells. | 1980 | Am. J. Physiol. | pmid:7435640 |
Plishker GA et al. | Involvement of a cytoplasmic protein in calcium-dependent potassium efflux in red blood cells. | 1986 | Am. J. Physiol. | pmid:3532815 |
Fiddian-Green RG and Silen W | Mechanisms of disposal of acid and alkali in rabbit duodenum. | 1975 | Am. J. Physiol. | pmid:2019 |
Griendling KK et al. | Pregnancy-induced changes in sheep uterine and carotid arteries. | 1985 | Am. J. Physiol. | pmid:2581458 |
Ramp WK and Demaree DN | Inhibition of net calcium efflux from bone by ethanol in vitro. | 1984 | Am. J. Physiol. | pmid:6696057 |
Wendt IR and Chapman JB | Fluorometric studies of recovery metabolism of rat fast- and slow-twitch muscles. | 1976 | Am. J. Physiol. | pmid:937554 |
Wendt IR and Gibbs CL | Recovery heat production of mammalian fast- and slow-twitch muscles. | 1976 | Am. J. Physiol. | pmid:937562 |
Beauwens R et al. | Polycations reduce vasopressin-induced water flow by endocytic removal of water channels. | 1986 | Am. J. Physiol. | pmid:3010730 |
Post JA et al. | pHe, [Ca2+]e, and cell death during metabolic inhibition: role of phospholipase A2 and sarcolemmal phospholipids. | 1998 | Am. J. Physiol. | pmid:9458847 |
Herchuelz A and Malaisse WJ | Regulation of calcium fluxes in pancreatic islets: two calcium movements' dissociated response to glucose. | 1980 | Am. J. Physiol. | pmid:6767412 |
Sick TJ et al. | Brain potassium ion homeostasis, anoxia, and metabolic inhibition in turtles and rats. | 1982 | Am. J. Physiol. | pmid:6287869 |
Shryock JC et al. | Release of adenosine from pig aortic endothelial cells during hypoxia and metabolic inhibition. | 1988 | Am. J. Physiol. | pmid:3344813 |
Yokozeki H et al. | Partial purification and characterization of cysteine proteinases in eccrine sweat. | 1987 | Am. J. Physiol. | pmid:3109264 |
Chamberlin ME and Mandel LJ | Na+-K+-ATPase activity in medullary thick ascending limb during short-term anoxia. | 1987 | Am. J. Physiol. | pmid:3034075 |
DiGregorio KA et al. | Measurement of superoxide release from single pulmonary alveolar macrophages. | 1987 | Am. J. Physiol. | pmid:3035935 |
Steinberg H et al. | Depression of pulmonary 5-hydroxytryptamine uptake by metabolic inhibitors. | 1975 | Am. J. Physiol. | pmid:1130533 |
Stokes JB et al. | Purification of rat papillary collecting duct cells: functional and metabolic assessment. | 1987 | Am. J. Physiol. | pmid:3303974 |
Murphy E et al. | Biochemical and structural changes in cultured heart cells induced by metabolic inhibition. | 1987 | Am. J. Physiol. | pmid:3688218 |
Johnson V and Maack T | Renal extraction, filtration, absorption, and catabolism of growth hormone. | 1977 | Am. J. Physiol. | pmid:910912 |
Said HM and Redha R | A carrier-mediated system for transport of biotin in rat intestine in vitro. | 1987 | Am. J. Physiol. | pmid:3812688 |
Sahlin K et al. | Effects of lactic acid accumulation and ATP decrease on muscle tension and relaxation. | 1981 | Am. J. Physiol. | pmid:7212053 |
Sayeed MM | Alterations in cellular Ca2+ regulation in the liver in endotoxic shock. | 1986 | Am. J. Physiol. | pmid:3706573 |
Fang HK et al. | Cardiac contractile function during coronary stenosis in dogs: association of adenosine in glycolytic dependence. | 1997 | Am. J. Physiol. | pmid:9176286 |
Koss KL and Grubbs RD | Elevated extracellular Mg2+ increases Mg2+ buffering through a Ca-dependent mechanism in cardiomyocytes. | 1994 | Am. J. Physiol. | pmid:8074196 |
Gramolini A and Renaud JM | Blocking ATP-sensitive K+ channel during metabolic inhibition impairs muscle contractility. | 1997 | Am. J. Physiol. | pmid:9227423 |
Xie LH et al. | Development of inwardly rectifying K+ channel family in rat ventricular myocytes. | 1997 | Am. J. Physiol. | pmid:9139958 |
Pautler EL et al. | Modification of leucine transport across bovine pigment epithelium by metabolic stress. | 1989 | Am. J. Physiol. | pmid:2596588 |
Dobrin P and Canfield T | Identification of smooth muscle series elastic component in intact carotid artery. | 1977 | Am. J. Physiol. | pmid:190898 |
Hurwitz A | Drug uptake into everted intestinal sacs. II. Inhibition of secretion by hypertonicity. | 1979 | Am. J. Physiol. | pmid:35006 |
Selvaggio AM et al. | Mechanisms of H+ secretion by inner medullary collecting duct cells. | 1988 | Am. J. Physiol. | pmid:3348416 |
Hansen SP and Gesser H | Extracellular Ca2+, force, and energy state in cardiac tissue of rainbow trout. | 1987 | Am. J. Physiol. | pmid:3425763 |
Nakamura K et al. | Glycolysis is necessary to preserve myocardial Ca2+ homeostasis during beta-adrenergic stimulation. | 1993 | Am. J. Physiol. | pmid:8384419 |
Ahearn GA | Intestinal electrophysiology and transmural ion transport in freshwater prawns. | 1980 | Am. J. Physiol. | pmid:7395980 |
Okamoto K et al. | ATP from glycolysis is required for normal sodium homeostasis in resting fast-twitch rodent skeletal muscle. | 2001 | Am. J. Physiol. Endocrinol. Metab. | pmid:11500303 |
Harrison GJ et al. | Glycolytic buffering affects cardiac bioenergetic signaling and contractile reserve similar to creatine kinase. | 2003 | Am. J. Physiol. Heart Circ. Physiol. | pmid:12714331 |
Zhou L et al. | Impact of anaerobic glycolysis and oxidative substrate selection on contractile function and mechanical efficiency during moderate severity ischemia. | 2008 | Am. J. Physiol. Heart Circ. Physiol. | pmid:18660443 |
Raddatz E et al. | Differential contribution of mitochondria, NADPH oxidases, and glycolysis to region-specific oxidant stress in the anoxic-reoxygenated embryonic heart. | 2011 | Am. J. Physiol. Heart Circ. Physiol. | pmid:21193588 |
Chen F et al. | Effects of metabolic inhibition on conduction, Ca transients, and arrhythmia vulnerability in embryonic mouse hearts. | 2007 | Am. J. Physiol. Heart Circ. Physiol. | pmid:17660398 |
Singla DK et al. | TGF-β2 treatment enhances cytoprotective factors released from embryonic stem cells and inhibits apoptosis in infarcted myocardium. | 2011 | Am. J. Physiol. Heart Circ. Physiol. | pmid:21297031 |
Merker MP et al. | Intracellular redox status affects transplasma membrane electron transport in pulmonary arterial endothelial cells. | 2002 | Am. J. Physiol. Lung Cell Mol. Physiol. | pmid:11741813 |
Galli GL et al. | Ca2+ cycling in cardiomyocytes from a high-performance reptile, the varanid lizard (Varanus exanthematicus). | 2009 | Am. J. Physiol. Regul. Integr. Comp. Physiol. | pmid:19812356 |
Pilarski JQ et al. | Effects of aerobic and anaerobic metabolic inhibitors on avian intrapulmonary chemoreceptors. | 2009 | Am. J. Physiol. Regul. Integr. Comp. Physiol. | pmid:19297545 |
Cheng AM et al. | Energy dependence of restitution in the gastric mucosa. | 2001 | Am. J. Physiol., Cell Physiol. | pmid:11443042 |
Yanagawa N et al. | Riboflavin transport by isolated perfused rabbit renal proximal tubules. | 2000 | Am. J. Physiol., Cell Physiol. | pmid:11078692 |
Aromolaran AS et al. | Role of glycolytically generated ATP for CaMKII-mediated regulation of intracellular Ca2+ signaling in bovine vascular endothelial cells. | 2007 | Am. J. Physiol., Cell Physiol. | pmid:17344311 |
Gustafson SB et al. | Evaluation of intra-articularly administered sodium monoiodoacetate-induced chemical injury to articular cartilage of horses. | 1992 | Am. J. Vet. Res. | pmid:1497191 |
Yovich JV et al. | Effects of polysulfated glycosaminoglycan on chemical and physical defects in equine articular cartilage. | 1987 | Am. J. Vet. Res. | pmid:3662210 |
Roe SC et al. | Biomechanical properties of canine cortical bone allografts: effects of preparation and storage. | 1988 | Am. J. Vet. Res. | pmid:3041883 |
Nakai T et al. | Characterization of the hemolysin produced by haemophilus pleuropneumoniae. | 1983 | Am. J. Vet. Res. | pmid:6830024 |
Von Behren LA and Pesanti EL | Uptake and degradation of Pneumocystis carinii by macrophages in vitro. | 1978 | Am. Rev. Respir. Dis. | pmid:369410 |