Iodoacetic acid

Iodoacetic acid is a lipid of Fatty Acyls (FA) class. Iodoacetic acid is associated with abnormalities such as Photoreceptor degeneration and Post MI. The involved functions are known as Hypoxia, Glycolysis, Metabolic Inhibition, Oxidation and PTPS activity. Iodoacetic acid often locates in Extracellular, Muscle, Mitochondria, Cytoplasmic matrix and Tissue membrane. The associated genes with Iodoacetic acid are SLC33A1 gene, GTF2I gene, Mutant Proteins, TRIM33 gene and oxytocin, 1-desamino-(O-Et-Tyr)(2)-.

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Introduction

To understand associated biological information of Iodoacetic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Iodoacetic acid?

Iodoacetic acid is suspected in Photoreceptor degeneration, Post MI and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Iodoacetic acid

MeSH term MeSH ID Detail
Arthritis, Experimental D001169 24 associated lipids
Blindness D001766 6 associated lipids
Blood Platelet Disorders D001791 12 associated lipids
Brain Edema D001929 20 associated lipids
Burns D002056 34 associated lipids
Byssinosis D002095 11 associated lipids
Brain Ischemia D002545 89 associated lipids
Clonorchiasis D003003 1 associated lipids
Coronary Disease D003327 70 associated lipids
Epilepsy D004827 35 associated lipids
Leukemia, Erythroblastic, Acute D004915 41 associated lipids
Glioma D005910 112 associated lipids
Glycogen Storage Disease D006008 4 associated lipids
Hemolysis D006461 131 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Hyperalgesia D006930 42 associated lipids
Hyperlipidemias D006949 73 associated lipids
Hypocalcemia D006996 12 associated lipids
Inflammation D007249 119 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Leukemia, Experimental D007942 42 associated lipids
Liver Neoplasms, Experimental D008114 46 associated lipids
Lung Neoplasms D008175 171 associated lipids
Lymphoma D008223 18 associated lipids
Mammary Neoplasms, Experimental D008325 67 associated lipids
Muscle Cramp D009120 3 associated lipids
Nerve Degeneration D009410 53 associated lipids
Osteoarthritis D010003 4 associated lipids
Pain D010146 64 associated lipids
Photosensitivity Disorders D010787 8 associated lipids
Pre-Eclampsia D011225 16 associated lipids
Cumulative Trauma Disorders D012090 2 associated lipids
Retinitis D012173 4 associated lipids
Rickets D012279 6 associated lipids
Rigor Mortis D012298 1 associated lipids
Sarcoma 180 D012510 21 associated lipids
Starvation D013217 47 associated lipids
Temporomandibular Joint Disorders D013705 4 associated lipids
Theileriasis D013801 7 associated lipids
Thrombocytopenia D013921 15 associated lipids
Thymus Neoplasms D013953 15 associated lipids
Vascular Diseases D014652 16 associated lipids
Vitamin D Deficiency D014808 13 associated lipids
Wounds and Injuries D014947 20 associated lipids
Reperfusion Injury D015427 65 associated lipids
Hypertrophy, Left Ventricular D017379 12 associated lipids
Arthralgia D018771 8 associated lipids
Thrombophilia D019851 6 associated lipids
Osteoarthritis, Knee D020370 13 associated lipids
Stroke D020521 32 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Iodoacetic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Iodoacetic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Iodoacetic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Iodoacetic acid?

There are no associated biomedical information in the current reference collection.

What genes are associated with Iodoacetic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Iodoacetic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Iodoacetic acid

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Per page 10 20 50 100 | Total 2490
Authors Title Published Journal PubMed Link
Gallis JL et al. A metabolic link between mitochondrial ATP synthesis and liver glycogen metabolism: NMR study in rats re-fed with butyrate and/or glucose. 2011 Nutr Metab (Lond) pmid:21676253
Horisaki T et al. Isolation and characterization of monochloroacetic acid-degrading bacteria. 2011 J. Gen. Appl. Microbiol. pmid:22139456
Raddatz E et al. Differential contribution of mitochondria, NADPH oxidases, and glycolysis to region-specific oxidant stress in the anoxic-reoxygenated embryonic heart. 2011 Am. J. Physiol. Heart Circ. Physiol. pmid:21193588
Huang J et al. Isolation, characterization and identification of a Paracoccus sp. 2-haloacid-degrading bacterium from the marine sponge Hymeniacidon perlevis. 2011 J. Basic Microbiol. pmid:21298680
Schuelert N et al. Local application of the endocannabinoid hydrolysis inhibitor URB597 reduces nociception in spontaneous and chemically induced models of osteoarthritis. 2011 Pain pmid:21185649
Sacks DB et al. Guidelines and recommendations for laboratory analysis in the diagnosis and management of diabetes mellitus. 2011 Diabetes Care pmid:21617108
Yamairi F et al. Expression of vascular endothelial growth factor (VEGF) associated with histopathological changes in rodent models of osteoarthritis. 2011 J Toxicol Pathol pmid:22272053
Hagen KD et al. Novel structural components of the ventral disc and lateral crest in Giardia intestinalis. 2011 PLoS Negl Trop Dis pmid:22206034
Chen Q et al. A novel neurotrophic drug for cognitive enhancement and Alzheimer's disease. 2011 PLoS ONE pmid:22194796
Mohan G et al. Application of in vivo micro-computed tomography in the temporal characterisation of subchondral bone architecture in a rat model of low-dose monosodium iodoacetate-induced osteoarthritis. 2011 Arthritis Res. Ther. pmid:22185204
Lee M et al. Direct sensing of endothelial oxidants by vascular endothelial growth factor receptor-2 and c-Src. 2011 PLoS ONE pmid:22145046
Potera C Nontoxic medical imaging agents form toxic DBPs. 2011 Environ. Health Perspect. pmid:22134135
House SA et al. Giardia flagellar motility is not directly required to maintain attachment to surfaces. 2011 PLoS Pathog. pmid:21829364
Yu J et al. Mussel protein adhesion depends on interprotein thiol-mediated redox modulation. 2011 Nat. Chem. Biol. pmid:21804534
Li A et al. Serotonin Receptor 2A/C Is Involved in Electroacupuncture Inhibition of Pain in an Osteoarthritis Rat Model. 2011 Evid Based Complement Alternat Med pmid:21799685
Woo YJ et al. Grape seed proanthocyanidin extract ameliorates monosodium iodoacetate-induced osteoarthritis. 2011 Exp. Mol. Med. pmid:21795829
Chhabra SR et al. Towards a rigorous network of protein-protein interactions of the model sulfate reducer Desulfovibrio vulgaris Hildenborough. 2011 PLoS ONE pmid:21738675
Li S et al. A new mutation affecting FRQ-less rhythms in the circadian system of Neurospora crassa. 2011 PLoS Genet. pmid:21731506
Moreau M et al. Tiludronate treatment improves structural changes and symptoms of osteoarthritis in the canine anterior cruciate ligament model. 2011 Arthritis Res. Ther. pmid:21693018
Stitham J et al. Prostacyclin: an inflammatory paradox. 2011 Front Pharmacol pmid:21687516
Phrommao E et al. A novel subtilase with NaCl-activated and oxidant-stable activity from Virgibacillus sp. SK37. 2011 BMC Biotechnol. pmid:21658261
Shen Y et al. Effect of Guanabenz on Rat AMD Models and Rabbit Choroidal Blood Flow. 2011 Open Ophthalmol J pmid:21633720
Valdes AM et al. The Ile585Val TRPV1 variant is involved in risk of painful knee osteoarthritis. 2011 Ann. Rheum. Dis. pmid:21616913
Palaniappan KK et al. Isotopic signature transfer and mass pattern prediction (IsoStamp): an enabling technique for chemically-directed proteomics. 2011 ACS Chem. Biol. pmid:21604797
Lee Y et al. Monosodium iodoacetate-induced joint pain is associated with increased phosphorylation of mitogen activated protein kinases in the rat spinal cord. 2011 Mol Pain pmid:21599960
Singla DK et al. TGF-β2 treatment enhances cytoprotective factors released from embryonic stem cells and inhibits apoptosis in infarcted myocardium. 2011 Am. J. Physiol. Heart Circ. Physiol. pmid:21297031
Jufvas A et al. Histone variants and their post-translational modifications in primary human fat cells. 2011 PLoS ONE pmid:21249133
Liu P et al. Ongoing pain in the MIA model of osteoarthritis. 2011 Neurosci. Lett. pmid:21241772
Dionisio G et al. Cloning and characterization of purple acid phosphatase phytases from wheat, barley, maize, and rice. 2011 Plant Physiol. pmid:21220762
Stevenson GW et al. Monosodium iodoacetate-induced osteoarthritis produces pain-depressed wheel running in rats: implications for preclinical behavioral assessment of chronic pain. 2011 Pharmacol. Biochem. Behav. pmid:21147151
Al-Jallad HF et al. Plasma membrane factor XIIIA transglutaminase activity regulates osteoblast matrix secretion and deposition by affecting microtubule dynamics. 2011 PLoS ONE pmid:21283799
Ferland CE et al. Determination of specific neuropeptides modulation time course in a rat model of osteoarthritis pain by liquid chromatography ion trap mass spectrometry. 2011 Neuropeptides pmid:21855139
Plewa MJ et al. Mammalian cell cytotoxicity and genotoxicity of the haloacetic acids, a major class of drinking water disinfection by-products. 2010 Oct-Dec Environ. Mol. Mutagen. pmid:20839218
Lim KM et al. Low-level mercury can enhance procoagulant activity of erythrocytes: a new contributing factor for mercury-related thrombotic disease. 2010 Environ. Health Perspect. pmid:20308036
Shirran SL and Botting CH A comparison of the accuracy of iTRAQ quantification by nLC-ESI MSMS and nLC-MALDI MSMS methods. 2010 J Proteomics pmid:20230925
McGaraughty S et al. TRPA1 modulation of spontaneous and mechanically evoked firing of spinal neurons in uninjured, osteoarthritic, and inflamed rats. 2010 Mol Pain pmid:20205719
Mann K et al. Phosphoproteomes of Strongylocentrotus purpuratus shell and tooth matrix: identification of a major acidic sea urchin tooth phosphoprotein, phosphodontin. 2010 Proteome Sci pmid:20181113
Calmettes G et al. Improved energy supply regulation in chronic hypoxic mouse counteracts hypoxia-induced altered cardiac energetics. 2010 PLoS ONE pmid:20174637
Edes K et al. JS-K, a nitric oxide prodrug, has enhanced cytotoxicity in colon cancer cells with knockdown of thioredoxin reductase 1. 2010 PLoS ONE pmid:20098717
Kawase N et al. Collagenolytic activity in sonic extracts of Tannerella forsythia. 2010 Arch. Oral Biol. pmid:20619781
Puntel RL et al. Mitochondrial dysfunction induced by different organochalchogens is mediated by thiol oxidation and is not dependent of the classical mitochondrial permeability transition pore opening. 2010 Toxicol. Sci. pmid:20573786
Liu H et al. Domain-level stability of an antibody monitored by reduction, differential alkylation, and mass spectrometry analysis. 2010 Anal. Biochem. pmid:20152794
Chu CR et al. In vivo effects of single intra-articular injection of 0.5% bupivacaine on articular cartilage. 2010 J Bone Joint Surg Am pmid:20194318
Peyfoon E et al. The S-layer glycoprotein of the crenarchaeote Sulfolobus acidocaldarius is glycosylated at multiple sites with chitobiose-linked N-glycans. 2010 Archaea pmid:20936123
Sniekers YH et al. Oestrogen is important for maintenance of cartilage and subchondral bone in a murine model of knee osteoarthritis. 2010 Arthritis Res. Ther. pmid:20923566
Bittner CX et al. High resolution measurement of the glycolytic rate. 2010 Front Neuroenergetics pmid:20890447
Schuelert N et al. Paradoxical effects of the cannabinoid CB2 receptor agonist GW405833 on rat osteoarthritic knee joint pain. 2010 Osteoarthr. Cartil. pmid:20863899
Eby WM et al. Hyperbolastic modeling of tumor growth with a combined treatment of iodoacetate and dimethylsulphoxide. 2010 BMC Cancer pmid:20863400
Li SC et al. Chicken model of steroid-induced bone marrow adipogenesis using proteome analysis: a preliminary study. 2010 Proteome Sci pmid:20840762
Lin D et al. Cysteinyl peptide capture for shotgun proteomics: global assessment of chemoselective fractionation. 2010 J. Proteome Res. pmid:20731415