Iodoacetic acid is a lipid of Fatty Acyls (FA) class. Iodoacetic acid is associated with abnormalities such as Photoreceptor degeneration and Post MI. The involved functions are known as Hypoxia, Glycolysis, Metabolic Inhibition, Oxidation and PTPS activity. Iodoacetic acid often locates in Extracellular, Muscle, Mitochondria, Cytoplasmic matrix and Tissue membrane. The associated genes with Iodoacetic acid are SLC33A1 gene, GTF2I gene, Mutant Proteins, TRIM33 gene and oxytocin, 1-desamino-(O-Et-Tyr)(2)-.
To understand associated biological information of Iodoacetic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Iodoacetic acid is suspected in Photoreceptor degeneration, Post MI and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Iodoacetic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Yassin NZ et al. | Effect of a topical copper indomethacin gel on inflammatory parameters in a rat model of osteoarthritis. | 2015 | Drug Des Devel Ther | pmid:25792809 |
Wang S and Kaltashov IA | Identification of reduction-susceptible disulfide bonds in transferrin by differential alkylation using O(16)/O(18) labeled iodoacetic acid. | 2015 | J. Am. Soc. Mass Spectrom. | pmid:25716754 |
Sagar DR et al. | Dissecting the contribution of knee joint NGF to spinal nociceptive sensitization in a model of OA pain in the rat. | 2015 | Osteoarthr. Cartil. | pmid:25623624 |
Liu Y et al. | Activation of α7 nicotinic acetylcholine receptors prevents monosodium iodoacetate-induced osteoarthritis in rats. | 2015 | Cell. Physiol. Biochem. | pmid:25613062 |
Chiu PR et al. | Vitamin C Protects Chondrocytes against Monosodium Iodoacetate-Induced Osteoarthritis by Multiple Pathways. | 2016 | Int J Mol Sci | pmid:28035982 |
Yuan B et al. | The Role of Glucose Metabolism on Porcine Oocyte Cytoplasmic Maturation and Its Possible Mechanisms. | 2016 | PLoS ONE | pmid:27997591 |
Morais SV et al. | Osteoarthritis model induced by intra-articular monosodium iodoacetate in rats knee. | 2016 | Acta Cir Bras | pmid:27982265 |
Choi HS et al. | Protective Effect of Deer Bone Oil on Cartilage Destruction in Rats with Monosodium Iodoacetate (MIA)-Induced Osteoarthritis. | 2016 | Biol. Pharm. Bull. | pmid:27904047 |
Meesawatsom P et al. | Inhibitory effects of aspirin-triggered resolvin D1 on spinal nociceptive processing in rat pain models. | 2016 | J Neuroinflammation | pmid:27589850 |
Burston JJ et al. | Robust anti-nociceptive effects of monoacylglycerol lipase inhibition in a model of osteoarthritis pain. | 2016 | Br. J. Pharmacol. | pmid:27501482 |