Iodoacetic acid

Iodoacetic acid is a lipid of Fatty Acyls (FA) class. Iodoacetic acid is associated with abnormalities such as Photoreceptor degeneration and Post MI. The involved functions are known as Hypoxia, Glycolysis, Metabolic Inhibition, Oxidation and PTPS activity. Iodoacetic acid often locates in Extracellular, Muscle, Mitochondria, Cytoplasmic matrix and Tissue membrane. The associated genes with Iodoacetic acid are SLC33A1 gene, GTF2I gene, Mutant Proteins, TRIM33 gene and oxytocin, 1-desamino-(O-Et-Tyr)(2)-.

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Introduction

To understand associated biological information of Iodoacetic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Iodoacetic acid?

Iodoacetic acid is suspected in Photoreceptor degeneration, Post MI and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Iodoacetic acid

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Pain D010146 64 associated lipids
Lung Neoplasms D008175 171 associated lipids
Wounds and Injuries D014947 20 associated lipids
Burns D002056 34 associated lipids
Inflammation D007249 119 associated lipids
Reperfusion Injury D015427 65 associated lipids
Mammary Neoplasms, Experimental D008325 67 associated lipids
Sarcoma 180 D012510 21 associated lipids
Per page 10 20 50 100 | Total 54

PubChem Associated disorders and diseases

What pathways are associated with Iodoacetic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Iodoacetic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Iodoacetic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Iodoacetic acid?

There are no associated biomedical information in the current reference collection.

What genes are associated with Iodoacetic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Iodoacetic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Iodoacetic acid

Download all related citations
Per page 10 20 50 100 | Total 2490
Authors Title Published Journal PubMed Link
Wei Y et al. Transient Receptor Potential Vanilloid 5 Mediates Ca2+ Influx and Inhibits Chondrocyte Autophagy in a Rat Osteoarthritis Model. 2017 Cell. Physiol. Biochem. pmid:28535500
McDougall JJ et al. Lysophosphatidic acid provides a missing link between osteoarthritis and joint neuropathic pain. 2017 Osteoarthr. Cartil. pmid:27651153
Thirunavukkarasu K et al. Identification and pharmacological characterization of a novel inhibitor of autotaxin in rodent models of joint pain. 2017 Osteoarthr. Cartil. pmid:27638130
Chiu PR et al. Vitamin C Protects Chondrocytes against Monosodium Iodoacetate-Induced Osteoarthritis by Multiple Pathways. 2016 Int J Mol Sci pmid:28035982
Yuan B et al. The Role of Glucose Metabolism on Porcine Oocyte Cytoplasmic Maturation and Its Possible Mechanisms. 2016 PLoS ONE pmid:27997591
Morais SV et al. Osteoarthritis model induced by intra-articular monosodium iodoacetate in rats knee. 2016 Acta Cir Bras pmid:27982265
Choi HS et al. Protective Effect of Deer Bone Oil on Cartilage Destruction in Rats with Monosodium Iodoacetate (MIA)-Induced Osteoarthritis. 2016 Biol. Pharm. Bull. pmid:27904047
Meesawatsom P et al. Inhibitory effects of aspirin-triggered resolvin D1 on spinal nociceptive processing in rat pain models. 2016 J Neuroinflammation pmid:27589850
Burston JJ et al. Robust anti-nociceptive effects of monoacylglycerol lipase inhibition in a model of osteoarthritis pain. 2016 Br. J. Pharmacol. pmid:27501482
Otis C et al. Concurrent validity of different functional and neuroproteomic pain assessment methods in the rat osteoarthritis monosodium iodoacetate (MIA) model. 2016 Arthritis Res. Ther. pmid:27338815
Pitcher T et al. The Monoiodoacetate Model of Osteoarthritis Pain in the Mouse. 2016 J Vis Exp pmid:27214709
Ziaei A et al. Preliminary investigation of the effects of topical mixture of Lawsonia inermis L. and Ricinus communis L. leaves extract in treatment of osteoarthritis using MIA model in rats. 2016 Daru pmid:27142000
Abaei M et al. Neural correlates of hyperalgesia in the monosodium iodoacetate model of osteoarthritis pain. 2016 Mol Pain pmid:27068285
Miyamoto S et al. Intra-articular injection of mono-iodoacetate induces osteoarthritis of the hip in rats. 2016 BMC Musculoskelet Disord pmid:26992380
Nwosu LN et al. Blocking the tropomyosin receptor kinase A (TrkA) receptor inhibits pain behaviour in two rat models of osteoarthritis. 2016 Ann. Rheum. Dis. pmid:26286016
Yarmola EG et al. Magnetic Capture of a Molecular Biomarker from Synovial Fluid in a Rat Model of Knee Osteoarthritis. 2016 Ann Biomed Eng pmid:26136062
Jeong YJ et al. Anti-Osteoarthritic Effects of the Litsea japonica Fruit in a Rat Model of Osteoarthritis Induced by Monosodium Iodoacetate. 2015 PLoS ONE pmid:26244981
Ogbonna AC et al. Development of monosodium acetate-induced osteoarthritis and inflammatory pain in ageing mice. 2015 Age (Dordr) pmid:25971876
Yassin NZ et al. Effect of a topical copper indomethacin gel on inflammatory parameters in a rat model of osteoarthritis. 2015 Drug Des Devel Ther pmid:25792809
Wang S and Kaltashov IA Identification of reduction-susceptible disulfide bonds in transferrin by differential alkylation using O(16)/O(18) labeled iodoacetic acid. 2015 J. Am. Soc. Mass Spectrom. pmid:25716754