Iodoacetic acid

Iodoacetic acid is a lipid of Fatty Acyls (FA) class. Iodoacetic acid is associated with abnormalities such as Photoreceptor degeneration and Post MI. The involved functions are known as Hypoxia, Glycolysis, Metabolic Inhibition, Oxidation and PTPS activity. Iodoacetic acid often locates in Extracellular, Muscle, Mitochondria, Cytoplasmic matrix and Tissue membrane. The associated genes with Iodoacetic acid are SLC33A1 gene, GTF2I gene, Mutant Proteins, TRIM33 gene and oxytocin, 1-desamino-(O-Et-Tyr)(2)-.

Cross Reference

Introduction

To understand associated biological information of Iodoacetic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Iodoacetic acid?

Iodoacetic acid is suspected in Photoreceptor degeneration, Post MI and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Iodoacetic acid

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Pain D010146 64 associated lipids
Lung Neoplasms D008175 171 associated lipids
Wounds and Injuries D014947 20 associated lipids
Burns D002056 34 associated lipids
Inflammation D007249 119 associated lipids
Reperfusion Injury D015427 65 associated lipids
Mammary Neoplasms, Experimental D008325 67 associated lipids
Sarcoma 180 D012510 21 associated lipids
Per page 10 20 50 100 | Total 54

PubChem Associated disorders and diseases

What pathways are associated with Iodoacetic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Iodoacetic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with Iodoacetic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Iodoacetic acid?

There are no associated biomedical information in the current reference collection.

What genes are associated with Iodoacetic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Iodoacetic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Iodoacetic acid

Download all related citations
Per page 10 20 50 100 | Total 2490
Authors Title Published Journal PubMed Link
pmid:
Xiong H et al. Role of cysteine-82 in the catalytic mechanism of human S-adenosylmethionine decarboxylase. 1999 Biochemistry pmid:10029540
Harada T and Mino Y Some properties of p-coumarate decarboxylase from Cladosporium phlei. 1976 Can. J. Microbiol. pmid:10068
Boeck D and Grosch W [Glutathatione-dehydrogenase of wheat flour. Purification and properties (author's transl)]. 1976 Z Lebensm Unters Forsch pmid:1007616
Kinsland C et al. Overexpression of recombinant proteins with a C-terminal thiocarboxylate: implications for protein semisynthesis and thiamin biosynthesis. 1998 Protein Sci. pmid:10082383
Cooke RD et al. Purification and characterisation of polygalacturonases from a commercial Aspergillus niger preparation. 1976 Biochim. Biophys. Acta pmid:1009121
Rego AC et al. Distinct glycolysis inhibitors determine retinal cell sensitivity to glutamate-mediated injury. 1999 Neurochem. Res. pmid:10215508
Labib RS et al. Studies on extracellular proteases of Streptococcus sanguis. Purification and characterization of a human IgA1 specific protease. 1978 Biochim. Biophys. Acta pmid:102357
Sauermann G Studies on ribonucleic acid metabolism using nuclear columns. Release of rapidly labeled RNA from rat liver nuclei. 1976 Hoppe-Seyler's Z. Physiol. Chem. pmid:10244
Rector ES et al. A method for the preparation of protein-protein conjugates of predetermined composition. 1978 J. Immunol. Methods pmid:102705
Lokshina LA et al. [Isolation of a neutral histone-hydrolyzing protease from bovine spleen]. 1976 Biokhimiia pmid:1030647
Suzuki T An ultramicroscopic study on rigor mortis. 1976 Nov-Dec Forensic Sci pmid:1033890
Lu GW et al. Alteration of oxygen consumption and energy metabolism during repetitive exposure of mice to hypoxia. 1999 Neurochem. Res. pmid:10344590
Jörnvall H et al. Probe of beta-galactosidase structure with iodoacetate. Differential reactivity of thiol groups in wild-type and mutant forms of beta-galactosidase. 1978 Biochemistry pmid:103570
Duncan R and Lloyd JB Pinocytosis in the rat visceral yolk sac. Effects of temperature, metabolic inhibitors and some other modifiers. 1978 Biochim. Biophys. Acta pmid:103581
Hellsten Y The effect of muscle contraction on the regulation of adenosine formation in rat skeletal muscle cells. 1999 J. Physiol. (Lond.) pmid:10420012
Rivett DE and Peet DJ Fatty acids chemically bound to protein forms the hydrophic membrane of the hair cuticle. 1999 Exp. Dermatol. pmid:10439276
Yang XJ et al. Hypothalamic glucose sensor: similarities to and differences from pancreatic beta-cell mechanisms. 1999 Diabetes pmid:10480606
Suzuki S et al. Difference in the effect of phloridzin on alveolar fluid absorption in anesthetized rats and in ex vivo rat lungs. 1999 Jul-Aug Exp. Lung Res. pmid:10483523
Balijepalli S et al. Effect of thiol modification on brain mitochondrial complex I activity. 1999 Neurosci. Lett. pmid:10505616
Chave KJ et al. Site-directed mutagenesis establishes cysteine-110 as essential for enzyme activity in human gamma-glutamyl hydrolase. 1999 Biochem. J. pmid:10527932
Patel AB et al. Arginine acts as a protective and reversal agent against glycolytic inhibitors in spermatozoa. 1999 Physiol Chem Phys Med NMR pmid:10535103
Lai SL et al. Interprotein disulfide bonds formed during isolation process tighten the structure of the postsynaptic density. 1999 J. Neurochem. pmid:10537073
Dirksen TR et al. Effect of metabolic inhibitors on bone lipid synthesis from radioactive bases. 1975 Sep-Oct J. Dent. Res. pmid:1058850
Chang YS et al. Shear-induced increase in hydraulic conductivity in endothelial cells is mediated by a nitric oxide-dependent mechanism. 2000 Arterioscler. Thromb. Vasc. Biol. pmid:10634798
Malcolm CS et al. Characterization of iodoacetate-mediated neurotoxicity in vitro using primary cultures of rat cerebellar granule cells. 2000 Free Radic. Biol. Med. pmid:10656296
Sinclair CJ et al. Stimulation of nucleoside efflux and inhibition of adenosine kinase by A1 adenosine receptor activation. 2000 Biochem. Pharmacol. pmid:10660114
Kim JS and Southard JH Effect of phospholipase A2 inhibitors on the release of arachidonic acid and cell viability in cold-stored hepatocytes. 2000 Cryobiology pmid:10679147
Yoshioka K et al. Characteristics of monocarboxylates as energy substrates other than glucose in rat brain slices and the effect of selective glial poisoning - a 31P NMR study. 2000 Neurosci. Res. pmid:10683525
Nagano H and To KA Purification of collagenase and specificity of its related enzyme from Bacillus subtilis FS-2. 2000 Biosci. Biotechnol. Biochem. pmid:10705465
López M et al. The action of Lonomia achelous caterpillars venom on human factor V. 2000 Thromb. Res. pmid:10706938
Miyagi M and Misono KS Disulfide bond structure of the atrial natriuretic peptide receptor extracellular domain: conserved disulfide bonds among guanylate cyclase-coupled receptors. 2000 Biochim. Biophys. Acta pmid:10719172
Hung AC et al. ATP-stimulated c-fos and zif268 mRNA expression is inhibited by chemical hypoxia in a rat brain-derived type 2 astrocyte cell line, RBA-2. 2000 J. Cell. Biochem. pmid:10723097
Koiwai H et al. Functional expression of two Arabidopsis aldehyde oxidases in the yeast Pichia pastoris. 2000 J. Biochem. pmid:10739959
Rasmussen JT et al. Cysteines involved in the interconversion between dehydrogenase and oxidase forms of bovine xanthine oxidoreductase. 2000 J. Dairy Sci. pmid:10750108
Martínez AD and Sáez JC Regulation of astrocyte gap junctions by hypoxia-reoxygenation. 2000 Brain Res. Brain Res. Rev. pmid:10751675
Larionova NA [The lipid composition characteristics of the blood serum and aortic wall in the modelling of different types of arteriosclerosis]. 2000 Fiziol Zh pmid:10758833
Bordji K et al. Evidence for the presence of peroxisome proliferator-activated receptor (PPAR) alpha and gamma and retinoid Z receptor in cartilage. PPARgamma activation modulates the effects of interleukin-1beta on rat chondrocytes. 2000 J. Biol. Chem. pmid:10766862
Abdel-Fattah AF and Badawi MA Effect of some agents on the activity of cell-free progesterone 11 alpha-hydroxylase and 11 beta-hydroxylase from Aspergillus niger 12Y. 1978 Zentralbl Bakteriol Naturwiss pmid:107681
Collard WT et al. Synthesis of homogeneous glycopeptides and their utility as DNA condensing agents. 2000 Carbohydr. Res. pmid:10782299
Hüser J et al. Functional coupling between glycolysis and excitation-contraction coupling underlies alternans in cat heart cells. 2000 J. Physiol. (Lond.) pmid:10790159
Bailey JR et al. Maintenance of resting tension in the american eel (Anguilla rostrata L.) heart is dependent upon exogenous fuel and the sarcoplasmic reticulum. 2000 J. Exp. Zool. pmid:10797323
Lapko VN et al. Identification of an artifact in the mass spectrometry of proteins derivatized with iodoacetamide. 2000 J Mass Spectrom pmid:10797654
Pannicke T et al. A function of delayed rectifier potassium channels in glial cells: maintenance of an auxiliary membrane potential under pathological conditions. 2000 Brain Res. pmid:10799684
Kulik A et al. Ischemia but not anoxia evokes vesicular and Ca(2+)-independent glutamate release in the dorsal vagal complex in vitro. 2000 J. Neurophysiol. pmid:10805687
Yoshisue K et al. Pharmacokinetics and biological fate of 3-(2,2, 2-trimethylhydrazinium)propionate dihydrate (MET-88), a novel cardioprotective agent, in rats. 2000 Drug Metab. Dispos. pmid:10820142
Mulvany MJ Mechanical properties of frog skeletal muscles in iodoacetic acid rigor. 1975 J. Physiol. (Lond.) pmid:1082023
Sahin-Tóth M and Kaback HR Functional conservation in the putative substrate binding site of the sucrose permease from Escherichia coli. 2000 Biochemistry pmid:10821691
Alvarado RH et al. Chloride transport across isolated skin of Rana pipiens. 1975 Am. J. Physiol. pmid:1082245
Varel VH and Miller DN Effect of antimicrobial agents on livestock waste emissions. 2000 Curr. Microbiol. pmid:10827282