Iodoacetic acid

Iodoacetic acid is a lipid of Fatty Acyls (FA) class. Iodoacetic acid is associated with abnormalities such as Photoreceptor degeneration and Post MI. The involved functions are known as Hypoxia, Glycolysis, Metabolic Inhibition, Oxidation and PTPS activity. Iodoacetic acid often locates in Extracellular, Muscle, Mitochondria, Cytoplasmic matrix and Tissue membrane. The associated genes with Iodoacetic acid are SLC33A1 gene, GTF2I gene, Mutant Proteins, TRIM33 gene and oxytocin, 1-desamino-(O-Et-Tyr)(2)-.

Cross Reference

Introduction

To understand associated biological information of Iodoacetic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Iodoacetic acid?

Iodoacetic acid is suspected in Photoreceptor degeneration, Post MI and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Iodoacetic acid

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Pain D010146 64 associated lipids
Lung Neoplasms D008175 171 associated lipids
Wounds and Injuries D014947 20 associated lipids
Burns D002056 34 associated lipids
Inflammation D007249 119 associated lipids
Reperfusion Injury D015427 65 associated lipids
Mammary Neoplasms, Experimental D008325 67 associated lipids
Sarcoma 180 D012510 21 associated lipids
Per page 10 20 50 100 | Total 54

PubChem Associated disorders and diseases

What pathways are associated with Iodoacetic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Iodoacetic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with Iodoacetic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Iodoacetic acid?

There are no associated biomedical information in the current reference collection.

What genes are associated with Iodoacetic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Iodoacetic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Iodoacetic acid

Download all related citations
Per page 10 20 50 100 | Total 2490
Authors Title Published Journal PubMed Link
Wolf MB and Baynes JW The anti-cancer drug, doxorubicin, causes oxidant stress-induced endothelial dysfunction. 2006 Biochim. Biophys. Acta pmid:16337743
Ralat LA and Colman RF Identification of tyrosine 79 in the tocopherol binding site of glutathione S-transferase pi. 2006 Biochemistry pmid:17029404
Herrmann L et al. Biochemical and molecular characterisation of Tetrahymena thermophila extracellular cysteine proteases. 2006 BMC Microbiol. pmid:16507097
Oestergaard S et al. The utility of measuring C-terminal telopeptides of collagen type II (CTX-II) in serum and synovial fluid samples for estimation of articular cartilage status in experimental models of destructive joint diseases. 2006 Osteoarthr. Cartil. pmid:16500121
Mastbergen SC et al. Differential direct effects of cyclo-oxygenase-1/2 inhibition on proteoglycan turnover of human osteoarthritic cartilage: an in vitro study. 2006 Arthritis Res. Ther. pmid:16356188
Bley KR et al. RO1138452 and RO3244794: characterization of structurally distinct, potent and selective IP (prostacyclin) receptor antagonists. 2006 Br. J. Pharmacol. pmid:16331286
Riley JK et al. Phosphatidylinositol 3-kinase activity is critical for glucose metabolism and embryo survival in murine blastocysts. 2006 J. Biol. Chem. pmid:16272157
Li S et al. Long-term storage of Clonorchis sinensis metacercariae in vitro. 2006 Parasitol. Res. pmid:16767424
Mejía-Toiber J et al. D-beta-hydroxybutyrate prevents glutamate-mediated lipoperoxidation and neuronal damage elicited during glycolysis inhibition in vivo. 2006 Neurochem. Res. pmid:17115265
Chapman JC et al. Mitochondrial 3 beta-hydroxysteroid dehydrogenase (HSD) is essential for the synthesis of progesterone by corpora lutea: an hypothesis. 2005 Reprod. Biol. Endocrinol. pmid:15804366
Rodrigo GC and Standen NB Role of mitochondrial re-energization and Ca2+ influx in reperfusion injury of metabolically inhibited cardiac myocytes. 2005 Cardiovasc. Res. pmid:15885675
Atsriku C et al. Reactivity of zinc finger cysteines: chemical modifications within labile zinc fingers in estrogen receptor. 2005 J. Am. Soc. Mass Spectrom. pmid:16246571
Unni E et al. Se-methylselenocysteine inhibits phosphatidylinositol 3-kinase activity of mouse mammary epithelial tumor cells in vitro. 2005 Breast Cancer Res. pmid:16168115
Nagahara N and Katayama A Post-translational regulation of mercaptopyruvate sulfurtransferase via a low redox potential cysteine-sulfenate in the maintenance of redox homeostasis. 2005 J. Biol. Chem. pmid:16107337
Byrd CM and Hruby DE Development of an in vitro cleavage assay system to examine vaccinia virus I7L cysteine proteinase activity. 2005 Virol. J. pmid:16105175
Libonati JR et al. Sprint training improves postischemic, left ventricular diastolic performance. 2005 J. Appl. Physiol. pmid:16037397
Wood JP et al. Energy substrate requirements for survival of rat retinal cells in culture: the importance of glucose and monocarboxylates. 2005 J. Neurochem. pmid:15836627
Morty RE et al. Identification of the reactive cysteine residues in oligopeptidase B from Trypanosoma brucei. 2005 FEBS Lett. pmid:15811340
Falchi AM et al. Characterization of depolarization and repolarization phases of mitochondrial membrane potential fluctuations induced by tetramethylrhodamine methyl ester photoactivation. 2005 FEBS J. pmid:15794752
Günzel D et al. Mg2+-malate co-transport, a mechanism for Na+-independent Mg2+ transport in neurons of the leech Hirudo medicinalis. 2005 J. Neurophysiol. pmid:15788520
Choi SJ et al. Effect of ketamine on apoptosis by energy deprivation in astroglioma cells using flow cytometry system. 2005 J. Korean Med. Sci. pmid:15716615
Kockskämper J et al. Modulation of sarcoplasmic reticulum Ca2+ release by glycolysis in cat atrial myocytes. 2005 J. Physiol. (Lond.) pmid:15695247
Winmill RE et al. Development of the respiratory response to hypoxia in the isolated brainstem of the bullfrog Rana catesbeiana. 2005 J. Exp. Biol. pmid:15634841
Palacios MC et al. Characterization of an acid phosphatase from Lactobacillus pentosus: regulation and biochemical properties. 2005 J. Appl. Microbiol. pmid:15610436
Meng TC et al. Development of a modified in-gel assay to identify protein tyrosine phosphatases that are oxidized and inactivated in vivo. 2005 Methods pmid:15588983
Perez E et al. Neuroprotective effects of an estratriene analog are estrogen receptor independent in vitro and in vivo. 2005 Brain Res. pmid:15757637
Rogel A et al. Phospholipase C is involved in the adenosine-activated signal transduction pathway conferring protection against iodoacetic acid-induced injury in primary rat neuronal cultures. 2005 Neurosci. Lett. pmid:15619546
Kim JY et al. Partial characterization of a 29 kDa cysteine protease purified from Taenia solium metacestodes. 2005 Korean J. Parasitol. pmid:16340305
Foucher B et al. [Stability of blood glucose collected with or without antiglycolytic agent]. 2004 Sep-Oct Ann. Biol. Clin. (Paris) pmid:15355815
Chung Y and Cho H Preparation of highly water soluble tacrolimus derivatives: poly(ethylene glycol) esters as potential prodrugs. 2004 Arch. Pharm. Res. pmid:15460452
Chung TH et al. 17beta-estradiol reduces the effect of metabolic inhibition on gap junction intercellular communication in rat cardiomyocytes via the estrogen receptor. 2004 J. Mol. Cell. Cardiol. pmid:15522278
Yang Y and Balcarcel RR 96-well plate assay for sublethal metabolic activity. 2004 Assay Drug Dev Technol pmid:15357916
Yang L et al. Purification and characterization of an isoflavone-conjugates-hydrolyzing beta-glucosidase from endophytic bacterium. 2004 J. Agric. Food Chem. pmid:15053533
Beauvieux MC et al. Some processes of energy saving and expenditure occurring during ethanol perfusion in the isolated liver of fed rats; a Nuclear Magnetic Resonance study. 2004 BMC Physiol. pmid:15053831
Lima-Catelani AR et al. Variation of genetic expression during development, revealed by esterase patterns in Aedes aegypti (Diptera, Culicidae). 2004 Biochem. Genet. pmid:15168721
Whitton C Chemical arthrodesis of the distal tarsal joints using sodium monoiodoacetate in 104 horses. 2004 Aust. Vet. J. pmid:15181929
Yep A et al. Identification and characterization of a critical region in the glycogen synthase from Escherichia coli. 2004 J. Biol. Chem. pmid:14665620
Song J et al. Isolation and characterization of an IAA-responsive gene from Gossypium barbadense L. 2004 DNA Seq. pmid:15354358
Nishida T et al. Regeneration of defects in articular cartilage in rat knee joints by CCN2 (connective tissue growth factor). 2004 J. Bone Miner. Res. pmid:15231019
Cylwik J et al. The influence of doxycycline on articular cartilage in experimental osteoarthrosis induced by iodoacetate. 2004 Folia Morphol. (Warsz) pmid:15232785
Persson C et al. Preferential oxidation of the second phosphatase domain of receptor-like PTP-alpha revealed by an antibody against oxidized protein tyrosine phosphatases. 2004 Proc. Natl. Acad. Sci. U.S.A. pmid:14762163
Hondorp ER and Matthews RG Oxidative stress inactivates cobalamin-independent methionine synthase (MetE) in Escherichia coli. 2004 PLoS Biol. pmid:15502870
Janusz MJ et al. Detection of aggrecanase- and MMP-generated catabolic neoepitopes in the rat iodoacetate model of cartilage degeneration. 2004 Osteoarthr. Cartil. pmid:15325638
Hiwatashi K et al. Purification and characterization of a novel prolyl aminopeptidase from Maitake (Grifola frondosa). 2004 Biosci. Biotechnol. Biochem. pmid:15215614
Pyza E and Górska-Andrzejak J Involvement of glial cells in rhythmic size changes in neurons of the housefly's visual system. 2004 J. Neurobiol. pmid:15085538
Rainbow RD et al. SUR2A C-terminal fragments reduce KATP currents and ischaemic tolerance of rat cardiac myocytes. 2004 J. Physiol. (Lond.) pmid:15020694
Dong L and Xu CW Carbohydrates induce mono-ubiquitination of H2B in yeast. 2004 J. Biol. Chem. pmid:14660635
Adachi T et al. S-Glutathiolation by peroxynitrite activates SERCA during arterial relaxation by nitric oxide. 2004 Nat. Med. pmid:15489859
Parkinson FE and Xiong W Stimulus- and cell-type-specific release of purines in cultured rat forebrain astrocytes and neurons. 2004 J. Neurochem. pmid:15009686
Dumond H et al. Site specific changes in gene expression and cartilage metabolism during early experimental osteoarthritis. 2004 Osteoarthr. Cartil. pmid:15023380
Renner R More chloramine complications. 2004 Environ. Sci. Technol. pmid:15487772
Shu W et al. [Study of preparation methods of polyclonal antibody of chymopapain]. 2004 Wei Sheng Yan Jiu pmid:15727194
Maekawa Y et al. A tetrazolium-based colorimetric assay for metabolic activity of stored blood platelets. 2003 Thromb. Res. pmid:12818255
Winkler BS et al. Modulation of the Pasteur effect in retinal cells: implications for understanding compensatory metabolic mechanisms. 2003 Exp. Eye Res. pmid:12742354
Harrison GJ et al. Glycolytic buffering affects cardiac bioenergetic signaling and contractile reserve similar to creatine kinase. 2003 Am. J. Physiol. Heart Circ. Physiol. pmid:12714331
Espelt MV et al. Volumetric and ionic responses of goldfish hepatocytes to anisotonic exposure and energetic limitation. 2003 J. Exp. Biol. pmid:12502772
Ding PZ An investigation of cysteine mutants on the cytoplasmic loop X/XI in the melibiose transporter of Escherichia coli by using thiol reagents: implication of structural conservation of charged residues. 2003 Biochem. Biophys. Res. Commun. pmid:12878191
Tůmová L et al. [Iodoacetic acid as a potential elicitor of increased production of flavonoids in a culture of Ononis arvensis L. in vitro]. 2003 Ceska Slov Farm pmid:12924071
Fadda S et al. Preliminary characterization of beta-decarboxylase activities in Staphylococcus carnosus 833, a strain used in sausage fermentation. 2003 FEMS Microbiol. Lett. pmid:14612250
Massieu L et al. Acetoacetate protects hippocampal neurons against glutamate-mediated neuronal damage during glycolysis inhibition. 2003 Neuroscience pmid:12890508
Bürkert E et al. The C2-like beta-barrel domain mediates the Ca2+-dependent resistance of 5-lipoxygenase activity against inhibition by glutathione peroxidase-1. 2003 J. Biol. Chem. pmid:12893830
Zhang Q et al. Purification and characterization of a novel carbaryl hydrolase from Aspergillus niger PY168. 2003 FEMS Microbiol. Lett. pmid:14612234
Jha S et al. Covalent modification of cysteine 193 impairs ATPase function of nucleotide-binding domain of a Candida drug efflux pump. 2003 Biochem. Biophys. Res. Commun. pmid:14550284
Adinarayana K et al. Purification and partial characterization of thermostable serine alkaline protease from a newly isolated Bacillus subtilis PE-11. 2003 AAPS PharmSciTech pmid:15198551
Bove SE et al. Weight bearing as a measure of disease progression and efficacy of anti-inflammatory compounds in a model of monosodium iodoacetate-induced osteoarthritis. 2003 Osteoarthr. Cartil. pmid:14609535
Vera PL and Meyer-Siegler KL Anatomical location of macrophage migration inhibitory factor in urogenital tissues, peripheral ganglia and lumbosacral spinal cord of the rat. 2003 BMC Neurosci pmid:12908877
Wentzel P et al. Maternal diabetes in vivo and high glucose in vitro diminish GAPDH activity in rat embryos. 2003 Diabetes pmid:12716756
Ito K et al. Novel aminopeptidase specific for glycine from Actinomucor elegans. 2003 Biosci. Biotechnol. Biochem. pmid:12619677
Newcomb LL et al. Glucose regulation of Saccharomyces cerevisiae cell cycle genes. 2003 Eukaryotic Cell pmid:12582131
Di-Capua N et al. Protein kinase C-epsilon is involved in the adenosine-activated signal transduction pathway conferring protection against ischemia-reperfusion injury in primary rat neuronal cultures. 2003 J. Neurochem. pmid:12559003
Kim YJ Partial inhibition of biohydrogenation of linoleic acid can increase the conjugated linoleic acid production of Butyrivibrio fibrisolvens A38. 2003 J. Agric. Food Chem. pmid:12848494
Damon BM et al. The carnosine C-2 proton's chemical shift reports intracellular pH in oxidative and glycolytic muscle fibers. 2003 Magn Reson Med pmid:12541242
Müller M and Ballanyi K Dynamic recording of cell death in the in vitro dorsal vagal nucleus of rats in response to metabolic arrest. 2003 J. Neurophysiol. pmid:12522201
Kito Y and Suzuki H Pacemaker frequency is increased by sodium nitroprusside in the guinea pig gastric antrum. 2003 J. Physiol. (Lond.) pmid:12509488
Ikemoto A et al. Glycolysis and glutamate accumulation into synaptic vesicles. Role of glyceraldehyde phosphate dehydrogenase and 3-phosphoglycerate kinase. 2003 J. Biol. Chem. pmid:12488440
Figueirêdo PM et al. Thiol-independent activity of a cholesterol-binding enterohemolysin produced by enteropathogenic Escherichia coli. 2003 Braz. J. Med. Biol. Res. pmid:14576905
Sugisawa T and Hoshino T Purification and properties of membrane-bound D-sorbitol dehydrogenase from Gluconobacter suboxydans IFO 3255. 2002 Biosci. Biotechnol. Biochem. pmid:11866120
Bogliolo M et al. Alternative metabolic pathways for energy supply and resistance to apoptosis in Fanconi anaemia. 2002 Mutagenesis pmid:11752230
Yang NC et al. ATP depletion is an important factor in DHEA-induced growth inhibition and apoptosis in BV-2 cells. 2002 Life Sci. pmid:12148690
Matsuki N et al. Catabolism of cytoplasmic and intramitochondrial adenine nucleotides in C2C12 skeletal myotube under chemical hypoxia. 2002 J. Vet. Med. Sci. pmid:12014580
Rodrigo GC et al. Dinitrophenol pretreatment of rat ventricular myocytes protects against damage by metabolic inhibition and reperfusion. 2002 J. Mol. Cell. Cardiol. pmid:12056859
Luchnik NV [Phenomenon of pseudomutagenesis: experiments with modifiers of cell metabolism in human lymphocytes]. 2002 Genetika pmid:12449644
Battista N et al. Anandamide uptake by synaptosomes from human, mouse and rat brain: inhibition by glutamine and glutamate. 2002 Lipids Health Dis pmid:12617751
Peral MJ et al. Human, rat and chicken small intestinal Na+ - Cl- -creatine transporter: functional, molecular characterization and localization. 2002 J. Physiol. (Lond.) pmid:12433955
Jung J et al. Interaction of cofilin with triose-phosphate isomerase contributes glycolytic fuel for Na,K-ATPase via Rho-mediated signaling pathway. 2002 J. Biol. Chem. pmid:12359716
Moreira CR et al. Identification of prolylcarboxypeptidase as the cell matrix-associated prekallikrein activator. 2002 FEBS Lett. pmid:12123826
Lawrence CL et al. Effect of metabolic inhibition on glimepiride block of native and cloned cardiac sarcolemmal K(ATP) channels. 2002 Br. J. Pharmacol. pmid:12086984
Vecchiarelli A et al. Antibody to Cryptococcus neoformans capsular glucuronoxylomannan promotes expression of interleukin-12Rbeta2 subunit on human T cells in vitro through effects mediated by antigen-presenting cells. 2002 Immunology pmid:12047756
Maithal K et al. Inhibition of plasmodium falciparum triose-phosphate isomerase by chemical modification of an interface cysteine. Electrospray ionization mass spectrometric analysis of differential cysteine reactivities. 2002 J. Biol. Chem. pmid:12006590
Mizuno Y et al. Cysteine synthase of an extremely thermophilic bacterium, Thermus thermophilus HB8. 2002 Biosci. Biotechnol. Biochem. pmid:12005048
Merker MP et al. Intracellular redox status affects transplasma membrane electron transport in pulmonary arterial endothelial cells. 2002 Am. J. Physiol. Lung Cell Mol. Physiol. pmid:11741813
Takahashi S et al. Substrate-dependence of reduction of MTT: a tetrazolium dye differs in cultured astroglia and neurons. 2002 Neurochem. Int. pmid:11821152
VanPutte CL et al. Characterization of hepatic low-K(m) outer-ring deiodination in red drum (Sciaenops ocellatus). 2001 Comp. Biochem. Physiol. B, Biochem. Mol. Biol. pmid:11250536
Guo Z et al. Iodoacetate protects hippocampal neurons against excitotoxic and oxidative injury: involvement of heat-shock proteins and Bcl-2. 2001 J. Neurochem. pmid:11677264
Bubis J et al. Chemical modification of transducin with iodoacetic acid: transducin-alpha carboxymethylated at Cys(347) allows transducin binding to Light-activated rhodopsin but prevents its release in the presence of GTP. 2001 Arch. Biochem. Biophys. pmid:11697851
Boja ES and Fales HM Overalkylation of a protein digest with iodoacetamide. 2001 Anal. Chem. pmid:11510821
Lawrence CL et al. The KATP channel opener diazoxide protects cardiac myocytes during metabolic inhibition without causing mitochondrial depolarization or flavoprotein oxidation. 2001 Br. J. Pharmacol. pmid:11588107
Delgado EF et al. Properties of myofibril-bound calpain activity in longissimus muscle of callipyge and normal sheep. 2001 J. Anim. Sci. pmid:11518218
Leach RM et al. Divergent roles of glycolysis and the mitochondrial electron transport chain in hypoxic pulmonary vasoconstriction of the rat: identity of the hypoxic sensor. 2001 J. Physiol. (Lond.) pmid:11579170
Okamoto K et al. ATP from glycolysis is required for normal sodium homeostasis in resting fast-twitch rodent skeletal muscle. 2001 Am. J. Physiol. Endocrinol. Metab. pmid:11500303