6-aminohexanoic acid

6-aminohexanoic acid is a lipid of Fatty Acyls (FA) class. 6-aminohexanoic acid is associated with abnormalities such as Blood Clot, Myocardial Infarction, Cerebrovascular accident, Renal impairment and Scoliosis, unspecified. The involved functions are known as Fibrinolysis, Agent, Hemorrhage, plasminogen activation and inhibitors. 6-aminohexanoic acid often locates in Chest, Blood, Body tissue, peritoneal and Plasma membrane. The associated genes with 6-aminohexanoic acid are P4HTM gene, BSND gene, MTPN gene, NDUFS4 gene and Homologous Gene. The related lipids are Phosphatidylserines and Butyric Acid.

Cross Reference

Introduction

To understand associated biological information of 6-aminohexanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with 6-aminohexanoic acid?

6-aminohexanoic acid is suspected in Cerebrovascular accident, Blood Clot, Myocardial Infarction, Renal impairment, Thromboembolism, Postoperative myocardial infarction and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 6-aminohexanoic acid

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Uremia D014511 33 associated lipids
Stomach Ulcer D013276 75 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Sarcoma, Experimental D012513 13 associated lipids
Adenocarcinoma D000230 166 associated lipids
Lupus Erythematosus, Systemic D008180 43 associated lipids
Hyperglycemia D006943 21 associated lipids
Wounds and Injuries D014947 20 associated lipids
Kidney Neoplasms D007680 29 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with 6-aminohexanoic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with 6-aminohexanoic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with 6-aminohexanoic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with 6-aminohexanoic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with 6-aminohexanoic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with 6-aminohexanoic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with 6-aminohexanoic acid

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Authors Title Published Journal PubMed Link
Ljungh A Helicobacter pylori interactions with plasminogen. 2000 Methods pmid:10816376
Reuter SR et al. Selective arterial embolization for control of massive upper gastrointestinal bleeding. 1975 Am J Roentgenol Radium Ther Nucl Med pmid:1081839
Wang W et al. Cyclic peptides incorporating 4-carboxyphenylalanine and phosphotyrosine are potent inhibitors of pp60(c-)(src). 2000 Biochemistry pmid:10819990
Koutský J et al. [Plasminogen activator and other trypsin-like proteases in the uterus wall and their participation on the tissue bleeding (author's transl)]. 1975 Arch Gynakol pmid:1082328
Rao BH et al. Epsilon aminocaproic acid in paediatric cardiac surgery to reduce postoperative blood loss. 2000 Indian J. Med. Res. pmid:10824468
Saleem R et al. The effect of epsilon-aminocaproic acid on HemoSTATUS and kaolin-activated clotting time measurements. 2000 Anesth. Analg. pmid:10825308
Rajamohan G and Dikshit KL Role of the N-terminal region of staphylokinase (SAK): evidence for the participation of the N-terminal region of SAK in the enzyme-substrate complex formation. 2000 FEBS Lett. pmid:10838076
Ghosh K et al. Epsilon-aminocaproic acid inhibits the activity of factor VIII inhibitors in patients with severe haemophilia A in vivo and in vitro. 2000 Acta Haematol. pmid:10838448
Wells TJ A new concept in the control of acute gingival hemorrhage. 1976 J Oral Surg pmid:1083898
Fatah-Ardalani K et al. More porous fibrin gel structure obtained by interaction with Lys-plasminogen than with Glu-plasminogen. 2000 Blood Coagul. Fibrinolysis pmid:10847420
Kimura I et al. Vascular endothelial growth factor- and platelet-derived growth factor-angiogenesis depressed but fetal bovine serum-angiogenesis enhanced choroidal tissue cultures of streptozotocin-diabetic Wistar and GK rats. 2000 Int Angiol pmid:10853682
Lawiński M et al. [E-aminocaproic acid in the treatment of acute pancreatitis]. 1976 Pol Przegl Chir pmid:1085930
North MJ and Ashworth JM Inhibition of the development of the cellular slime mould Dictyostelium discoideum by omega-aminocarboxylic acids. 1976 J. Gen. Microbiol. pmid:1086340
North MJ and Campbell AJ The effect of epsilon-aminocaproic acid on biochemical changes in the development of the cellular slime mould Dictyostelium discoideum. 1976 J. Gen. Microbiol. pmid:1086341
Dalmau A et al. Tranexamic acid reduces red cell transfusion better than epsilon-aminocaproic acid or placebo in liver transplantation. 2000 Anesth. Analg. pmid:10866882
Vergoz D et al. Kasabach-kasabach-. 1976 Jan-Mar Phlebologie pmid:1087029
Kallmes DF et al. Adjuvant use of epsilon-aminocaproic acid (Amicar) in the endovascular treatment of cranial arteriovenous fistulae. 2000 Neuroradiology pmid:10872177
MacDonald M et al. Synthesis and conformation of Gly-Gly dipeptides constrained with phenylalanine-like aminocaproic acid linkers. 2000 Org. Lett. pmid:10880193
Kleking GR and Viurbakh G [Antifibrinolytic and antimycotic properties of 2-thiontetrahydro-1,3,5-thiadiazine]. 1976 Jun-Aug Farmakol Toksikol pmid:1088410
Ledoux D et al. Human plasmin enzymatic activity is inhibited by chemically modified dextrans. 2000 J. Biol. Chem. pmid:10889187
Goretzki L et al. Binding of the NG2 proteoglycan to kringle domains modulates the functional properties of angiostatin and plasmin(ogen). 2000 J. Biol. Chem. pmid:10889192
Gruber EM et al. Synthetic antifibrinolytics are not associated with an increased incidence of baffle fenestration closure after the modified Fontan procedure. 2000 J. Cardiothorac. Vasc. Anesth. pmid:10890476
Takahashi R et al. Affinity chromatography for purification of two urokinases from human urine. 2000 J. Chromatogr. B Biomed. Sci. Appl. pmid:10892585
Romano PE and Robinson JA Traumatic hyphema: a comprehensive review of the past half century yields 8076 cases for which specific medical treatment reduces rebleeding 62%, from 13% to 5% (P<.0001). 2000 Binocul Vis Strabismus Q pmid:10893461
Fukao H et al. Binding of mutant tissue-type plasminogen activators to human endothelial cells and their extracellular matrix. 2000 Life Sci. pmid:10894090
Cattaneo M and Mannucci PM Current status of non-transfusional haemostatic agents. 1999 Haematologica pmid:10907488
Zajicek J et al. The effects of ligand binding on the backbone dynamics of the kringle 1 domain of human plasminogen. 2000 J. Mol. Biol. pmid:10926513
Zhang WY et al. Plasmin-mediated macrophage reversal of low density lipoprotein aggregation. 2000 J. Biol. Chem. pmid:10942782
Horne MK et al. Comparison of the effect of histidine-rich glycoprotein and 6-aminohexanoic acid on plasmin production and fibrinolysis in vitro. 2000 Thromb. Res. pmid:10946092
Dekkers DW et al. Multidrug resistance protein 1 regulates lipid asymmetry in erythrocyte membranes. 2000 Biochem. J. pmid:10947968
Kornblatt JA Understanding the fluorescence changes of human plasminogen when it binds the ligand, 6-aminohexanoate: a synthesis. 2000 Biochim. Biophys. Acta pmid:10962086
Yarzábal A et al. A study of the interaction between Helicobacter pylori and components of the human fibrinolytic system. 2000 Braz. J. Med. Biol. Res. pmid:10973131
Hoffmann K et al. First non-radioactive assay for in vitro screening of histone deacetylase inhibitors. 2000 Pharmazie pmid:10989838
Hu B et al. Intervesicle cross-linking with integrin alpha IIb beta 3 and cyclic-RGD-lipopeptide. A model of cell-adhesion processes. 2000 Biochemistry pmid:11015207
Hawley SB et al. Purification, cloning, and characterization of a profibrinolytic plasminogen-binding protein, TIP49a. 2001 J. Biol. Chem. pmid:11027681
Maineri P et al. Postoperative bleeding after coronary revascularization. Comparison between tranexamic acid and epsilon-aminocaproic acid. 2000 Minerva Cardioangiol pmid:11048468
Stafford-Smith M et al. The association of epsilon-aminocaproic acid with postoperative decrease in creatinine clearance in 1502 coronary bypass patients. 2000 Anesth. Analg. pmid:11049888
Avilan L et al. Interaction of Leishmania mexicana promastigotes with the plasminogen-plasmin system. 2000 Mol. Biochem. Parasitol. pmid:11071275
Boxrud PD and Bock PE Streptokinase binds preferentially to the extended conformation of plasminogen through lysine binding site and catalytic domain interactions. 2000 Biochemistry pmid:11076540
Chauhan S et al. Efficacy of aprotinin, epsilon aminocaproic acid, or combination in cyanotic heart disease. 2000 Ann. Thorac. Surg. pmid:11081890
Hrabálek A et al. Esters of 6-dimethylaminohexanoic acid as skin penetration enhancers. 2000 Pharmazie pmid:11082838
Elliott JT and Prestwich GD Maleimide-functionalized lipids that anchor polypeptides to lipid bilayers and membranes. 2000 Nov-Dec Bioconjug. Chem. pmid:11087332
Mullan S Conservative management of the recently ruptured aneurysm. 1975 Surg Neurol pmid:1111142
Muneer E et al. Mechanism of enhancement by fucoidan and CNBr-fibrinogen digest of the activation of glu-plasminogen by tissue plasminogen activator. 2000 Apr-Jun Eur J Drug Metab Pharmacokinet pmid:11112095
Ries M et al. Differences between neonates and adults in the urokinase-plasminogen activator (u-PA) pathway of the fibrinolytic system. 2000 Thromb. Res. pmid:11113278
Minn SK and Mandel EE Experimental disseminated intravascular coagulation effect of heparin and epsilon-aminocaproic acid on tests of hemostatic function. 1975 Thromb. Res. pmid:1114490
Herren T et al. Regulation of plasminogen binding to neutrophils. 2001 Blood pmid:11159539
Khatib AM et al. Regulation of urokinase plasminogen activator/plasmin-mediated invasion of melanoma cells by the integrin vitronectin receptor alphaVbeta3. 2001 Int. J. Cancer pmid:11169951
Caster WO and Bleecker S Hyperglycemic effect of amino compounds structurally related to caproate in rats. 1975 J. Nutr. pmid:1117341
Vang SN et al. Co-administration of aprotinin and epsilon-aminocaproic acid during cardiopulmonary bypass in a swine model. 2000 J Extra Corpor Technol pmid:11194056