4-aminobutyric acid
4-aminobutyric acid is a lipid of Fatty Acyls (FA) class. 4-aminobutyric acid is associated with abnormalities such as Epilepsy and Premenstrual syndrome. The involved functions are known as Binding (Molecular Function), neuron survival, Process, Uptake and physiological aspects. 4-aminobutyric acid often locates in Microglial, Neurofilament, Neuraxis, Brain region and Neurites. The associated genes with 4-aminobutyric acid are arginine methyl ester, SLC33A1 gene, NKS1 gene, P4HTM gene and ITSN2 gene. The related lipids are pregnenolone sulfate, pregnane-20-one, Pregnanes, Steroids and endogenous steroids.
Cross Reference
Introduction
To understand associated biological information of 4-aminobutyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with 4-aminobutyric acid?
4-aminobutyric acid is suspected in Premenstrual syndrome, Epilepsy and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with 4-aminobutyric acid
PubChem Associated disorders and diseases
What pathways are associated with 4-aminobutyric acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with 4-aminobutyric acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with 4-aminobutyric acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with 4-aminobutyric acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with 4-aminobutyric acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with 4-aminobutyric acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with 4-aminobutyric acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Hammerstad JP and Lytle CR | Release of [3H] GABA from rat cortical slices: neuronal vs glial origin. | 1976 | J. Neurochem. | pmid:965982 |
| pmid:9659873 | ||||
| Atterwill CK and Neal MJ | The subcellular distribution of [14C] GABA and [3H] dopamine in the retina. | 1976 | J. Neurochem. | pmid:965995 |
| Sandoval ME et al. | Studies on the relationship between GABA synthesis and protein synthesis in brain. | 1976 | J. Neurochem. | pmid:966009 |
| Gottesfeld Z et al. | Changes in the GABA system in experimental allergic encephalomyelitis-induced paralysis. | 1976 | J. Neurochem. | pmid:966011 |
| De Mello FG et al. | Ornithine and glutamic acid decarboxylase activities in the developing chick retina. | 1976 | J. Neurochem. | pmid:966019 |
| Mattson ME and O'Brien RD | The binding of acetylcholine to synaptic vesicles from Torpedo californica electroplax. | 1976 | J. Neurochem. | pmid:966022 |
| Matin MA et al. | Modification of pp' DDT induced convulsions by changes in the level of cerebral gamma-aminobutyric acid in mice. | 1976 | J. Neurochem. | pmid:966034 |
| pmid:9660516 | ||||
| pmid:9660518 | ||||
| pmid:9660888 | ||||
| pmid:9660895 | ||||
| pmid:9660897 | ||||
| pmid:9661248 | ||||
| pmid:9661258 | ||||
| Sierra-Paredes G et al. | Extracellular amino acids in the rat hippocampus during picrotoxin threshold seizures in chronic microdialysis experiments. | 1998 | Neurosci. Lett. | pmid:9665662 |
| Jonas P et al. | Corelease of two fast neurotransmitters at a central synapse. | 1998 | Science | pmid:9665886 |
| Rao GP et al. | Study is needed of visual field defects associated with any long term antiepileptic drug. | 1998 | BMJ | pmid:9665915 |
| do Nascimento JL et al. | Veratridine- and glutamate-induced release of [3H]-GABA from cultured chick retina cells: possible involvement of a GAT-1-like subtype of GABA transporter. | 1998 | Brain Res. | pmid:9666133 |
| Phillips I et al. | GABA-evoked depolarisations in the rat cortical wedge: involvement of GABAA receptors and HCO3- ions. | 1998 | Brain Res. | pmid:9666162 |
| Morales M et al. | Acute ethanol induces c-fos immunoreactivity in GABAergic neurons of the central nucleus of the amygdala. | 1998 | Brain Res. | pmid:9666163 |
| Wu SM and Maple BR | Amino acid neurotransmitters in the retina: a functional overview. | 1998 | Vision Res. | pmid:9667005 |
| Huang LH et al. | Glutamatergic neurotransmission from the optic tectum to the contralateral nucleus rotundus in pigeons. | 1998 | Brain Behav. Evol. | pmid:9667809 |
| Borghese CM et al. | Lack of tolerance to the anxiolytic effect of diazepam and pentobarbital following chronic administration in perinatally undernourished rats. | 1998 | Brain Res. Bull. | pmid:9667818 |
| Kaluiev AV | GABA-ergic role in overlapping of memory and anxiety. | 1998 | Fiziol Zh | pmid:9669171 |
| Asahi M et al. | Induction of the N-methyl-D-aspartate receptor subunit 1 in the immortalized neuronal progenitor cell line HC2S2 during differentiation into neurons. | 1998 | J. Neurosci. Res. | pmid:9669319 |
| Sheikh SN and Martin DL | Elevation of brain GABA levels with vigabatrin (gamma-vinylGABA) differentially affects GAD65 and GAD67 expression in various regions of rat brain. | 1998 | J. Neurosci. Res. | pmid:9669322 |
| Kleinrok Z et al. | GABA content and GAD activity in colon tumors taken from patients with colon cancer or from xenografted human colon cancer cells growing as s.c. tumors in athymic nu/nu mice. | 1998 | J. Physiol. Pharmacol. | pmid:9670113 |
| Faingold CL et al. | Ethanol and neurotransmitter interactions--from molecular to integrative effects. | 1998 | Prog. Neurobiol. | pmid:9670216 |
| Davies P et al. | First one in, last one out: the role of gabaergic transmission in generation and degeneration. | 1998 | Prog. Neurobiol. | pmid:9670223 |
| Brook GA et al. | Spontaneous longitudinally orientated axonal regeneration is associated with the Schwann cell framework within the lesion site following spinal cord compression injury of the rat. | 1998 | J. Neurosci. Res. | pmid:9670992 |
| De Sarro G et al. | Gabapentin potentiates the antiseizure activity of certain anticonvulsants in DBA/2 mice. | 1998 | Eur. J. Pharmacol. | pmid:9671096 |
| McMahon LL et al. | Functionally distinct groups of interneurons identified during rhythmic carbachol oscillations in hippocampus in vitro. | 1998 | J. Neurosci. | pmid:9671655 |
| Christensen TA et al. | Multitasking in the olfactory system: context-dependent responses to odors reveal dual GABA-regulated coding mechanisms in single olfactory projection neurons. | 1998 | J. Neurosci. | pmid:9671685 |
| D'Amelio F et al. | Hypergravity exposure decreases gamma-aminobutyric acid immunoreactivity in axon terminals contacting pyramidal cells in the rat somatosensory cortex: a quantitative immunocytochemical image analysis. | 1998 | J. Neurosci. Res. | pmid:9671970 |
| Moore DB et al. | Prenatal ethanol exposure reduces parvalbumin-immunoreactive GABAergic neuronal number in the adult rat cingulate cortex. | 1998 | Neurosci. Lett. | pmid:9672380 |
| Herranz JL | [Tiagabine: recent findings and recommendations for dosage]. | 1998 | Rev Neurol | pmid:9674039 |
| Clarke NP and Bolam JP | Distribution of glutamate receptor subunits at neurochemically characterized synapses in the entopeduncular nucleus and subthalamic nucleus of the rat. | 1998 | J. Comp. Neurol. | pmid:9674565 |
| Tkatch T et al. | Basal forebrain neurons adjacent to the globus pallidus co-express GABAergic and cholinergic marker mRNAs. | 1998 | Neuroreport | pmid:9674570 |
| Gospe SM and Hecht ST | Longitudinal MRI findings in pyridoxine-dependent seizures. | 1998 | Neurology | pmid:9674782 |
| Floeter MK et al. | Physiologic studies of spinal inhibitory circuits in patients with stiff-person syndrome. | 1998 | Neurology | pmid:9674784 |
| Ifergane G et al. | Acute encephalopathy associated with vigabatrin monotherapy in patients with mild renal failure. | 1998 | Neurology | pmid:9674833 |
| Wetherton BM et al. | Structure and function of gustatory neurons in the nucleus of the solitary tract. III. Classification of terminals using cluster analysis. | 1998 | Biotech Histochem | pmid:9674887 |
| Tueth MJ et al. | Special considerations: use of lithium in children, adolescents, and elderly populations. | 1998 | J Clin Psychiatry | pmid:9674939 |
| Keck PE et al. | Anticonvulsants and antipsychotics in the treatment of bipolar disorder. | 1998 | J Clin Psychiatry | pmid:9674940 |
| Kobashi M and Bradley RM | Effects of GABA on neurons of the gustatory and visceral zones of the parabrachial nucleus in rats. | 1998 | Brain Res. | pmid:9675328 |
| pmid:9675429 | ||||
| pmid:9677144 | ||||
| pmid:9678632 | ||||
| pmid:9678653 | ||||
| pmid:9680244 | ||||
| pmid:9680261 | ||||
| pmid:9681405 | ||||
| pmid:9681479 | ||||
| pmid:9681574 | ||||
| pmid:9681936 | ||||
| pmid:9681963 | ||||
| pmid:9682190 | ||||
| pmid:9682629 | ||||
| pmid:9682809 | ||||
| pmid:9682875 | ||||
| pmid:9683011 | ||||
| pmid:9683315 | ||||
| pmid:9684157 | ||||
| Hu LA and King SC | Functional significance of the "signature cysteine" in helix 8 of the Escherichia coli 4-aminobutyrate transporter from the amine-polyamine-choline superfamily. Restoration of Cys-300 to the Cys-less Gabp. | 1998 | J. Biol. Chem. | pmid:9685361 |
| Löscher W et al. | Differences in the distribution of GABA- and GAD-immunoreactive neurons in the anterior and posterior piriform cortex of rats. | 1998 | Brain Res. | pmid:9685574 |
| Ding R et al. | Changes in extracellular glutamate and GABA levels in the hippocampal CA3 and CA1 areas and the induction of glutamic acid decarboxylase-67 in dentate granule cells of rats treated with kainic acid. | 1998 | Brain Res. | pmid:9685600 |
| Soldo BL et al. | Ethanol selectively enhances the hyperpolarizing component of neocortical neuronal responses to locally applied GABA. | 1998 | Brain Res. | pmid:9685636 |
| Calvo N et al. | Metyrapone pretreatment prevents the behavioral and neurochemical sequelae induced by stress. | 1998 | Brain Res. | pmid:9685654 |
| Le Moine C and Gaspar P | Subpopulations of cortical GABAergic interneurons differ by their expression of D1 and D2 dopamine receptor subtypes. | 1998 | Brain Res. Mol. Brain Res. | pmid:9685656 |
| Depaulis A et al. | [GABAergic mechanisms in generalized epilepsies: the neuroanatomical dimension]. | 1997 | Rev. Neurol. (Paris) | pmid:9686242 |
| Taylor CP | Mechanisms of action of gabapentin. | 1997 | Rev. Neurol. (Paris) | pmid:9686247 |
| Schulze A et al. | Disturbed metabolism of guanidino compounds characterized by elevated excretion of beta-guanidinopropionic acid and gamma-guanidinobutyric acid--an effect of vigabatrin treatment? | 1998 | J. Inherit. Metab. Dis. | pmid:9686372 |
| Bettler B et al. | GABAB receptors: drugs meet clones. | 1998 | Curr. Opin. Neurobiol. | pmid:9687348 |
| Bonnet U et al. | CO2/HCO3(-)-withdrawal from the bath medium of hippocampal slices: biphasic effect on intracellular pH and bioelectric activity of CA3-neurons. | 1998 | Brain Res. | pmid:9689466 |
| Pakaski M et al. | Vulnerability of small GABAergic neurons to human beta-amyloid pentapeptide. | 1998 | Brain Res. | pmid:9689474 |
| KerimovSA ChIu and Kasumov | [The effect of an extract of licorice root and of tetrachloroethylene vapors on the level of the mediators of amino acid structure in the brains of young animals]. | 1998 May-Jun | Eksp Klin Farmakol | pmid:9690080 |
| Sergeev LV et al. | [GABA receptors and the cardiovascular system]. | 1998 May-Jun | Eksp Klin Farmakol | pmid:9690086 |
| Horton RW and Meldrum BS | Catalytic inhibitors of GABA-transaminase as anticonvulsants in baboons with photosensitive epilepsy [proceedings]. | 1978 | Br. J. Pharmacol. | pmid:96902 |
| Valeyev AY et al. | Embryonic rat hippocampal neurons and GABAA receptor subunit-transfected non-neuronal cells release GABA tonically. | 1998 | J. Membr. Biol. | pmid:9691117 |
| Yarom M et al. | Identification of inosine as an endogenous modulator for the benzodiazepine binding site of the GABAA receptors. | 1998 Jul-Aug | J. Biomed. Sci. | pmid:9691220 |
| Malatynska E et al. | Schild regression analysis of antidepressant and bicuculline antagonist effects at the GABAA receptor. | 1998 | Pharmacology | pmid:9691231 |
| Larsen M et al. | Effect of isoflurane on release and uptake of gamma-aminobutyric acid from rat cortical synaptosomes. | 1998 | Br J Anaesth | pmid:9691868 |
| Shimazu T et al. | Cholinergic stimulation of the rat hypothalamus: effects of liver glycogen synthesis. | 1976 | Science | pmid:9692 |
| Kano T et al. | Effects of nitric oxide synthase gene knockout on neurotransmitter release in vivo. | 1998 | Neuroscience | pmid:9692709 |
| Khateb A et al. | GABAergic input to cholinergic nucleus basalis neurons. | 1998 | Neuroscience | pmid:9692729 |
| McLaughlin BA et al. | Methylmalonate toxicity in primary neuronal cultures. | 1998 | Neuroscience | pmid:9692761 |
| Kellogg CK et al. | Neurosteroid action at the GABAA receptor in fetal rat forebrain. | 1998 | Brain Res. Dev. Brain Res. | pmid:9693791 |
| Hagedorn M et al. | The embryogenesis of rod photoreceptors in the teleost fish retina, Haplochromis burtoni. | 1998 | Brain Res. Dev. Brain Res. | pmid:9693798 |
| Lim CH and Ho SM | GABAergic modulation of axonal conduction in the developing rat retinotectal pathway. | 1998 | Brain Res. Dev. Brain Res. | pmid:9693806 |
| Clayton GH et al. | Developmental expression of C1C-2 in the rat nervous system. | 1998 | Brain Res. Dev. Brain Res. | pmid:9693808 |
| MankovskiÄ NB et al. | [Effectiveness of gammalon and anticholinesterase preparations in the restorative and residual periods of ischemic stroke in old age]. | 1976 | Vrach Delo | pmid:969409 |
| Lainé J and Axelrad H | Lugaro cells target basket and stellate cells in the cerebellar cortex. | 1998 | Neuroreport | pmid:9694235 |
| Fienberg AA et al. | DARPP-32: regulator of the efficacy of dopaminergic neurotransmission. | 1998 | Science | pmid:9694658 |
| pmid:9694928 | ||||
| Korolkiewicz R et al. | Influence of intracerebroventricular administration of tetanus toxin on experimental seizures and protection afforded by some antiepileptic drugs in mice. | 1998 | Pharmacol. Res. | pmid:9695121 |
| Weber OM et al. | Detection of hidden metabolites by localized proton magnetic resonance spectroscopy in vivo. | 1997 | Technol Health Care | pmid:9696165 |
| Gibbs JW et al. | Physiological analysis of Rasmussen's encephalitis: patch clamp recordings of altered inhibitory neurotransmitter function in resected frontal cortical tissue. | 1998 | Epilepsy Res. | pmid:9696297 |
| Noachtar S et al. | Gabapentin and carbamazepine affect eye movements and posture control differently: a placebo-controlled investigation of acute CNS side effects in healthy volunteers. | 1998 | Epilepsy Res. | pmid:9696300 |
| Matagne A and Klitgaard H | Validation of corneally kindled mice: a sensitive screening model for partial epilepsy in man. | 1998 | Epilepsy Res. | pmid:9696301 |