4-aminobutyric acid
4-aminobutyric acid is a lipid of Fatty Acyls (FA) class. 4-aminobutyric acid is associated with abnormalities such as Epilepsy and Premenstrual syndrome. The involved functions are known as Binding (Molecular Function), neuron survival, Process, Uptake and physiological aspects. 4-aminobutyric acid often locates in Microglial, Neurofilament, Neuraxis, Brain region and Neurites. The associated genes with 4-aminobutyric acid are arginine methyl ester, SLC33A1 gene, NKS1 gene, P4HTM gene and ITSN2 gene. The related lipids are pregnenolone sulfate, pregnane-20-one, Pregnanes, Steroids and endogenous steroids.
Cross Reference
Introduction
To understand associated biological information of 4-aminobutyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with 4-aminobutyric acid?
4-aminobutyric acid is suspected in Premenstrual syndrome, Epilepsy and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with 4-aminobutyric acid
PubChem Associated disorders and diseases
What pathways are associated with 4-aminobutyric acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with 4-aminobutyric acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with 4-aminobutyric acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with 4-aminobutyric acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with 4-aminobutyric acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with 4-aminobutyric acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with 4-aminobutyric acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Casas S et al. | Neuromodulatory effect of progesterone on the dopaminergic, glutamatergic, and GABAergic activities in a male rat model of Parkinson's disease. | 2013 | Neurol. Res. | pmid:23561326 |
| Tian Z et al. | Estrogen receptor GPR30 exerts anxiolytic effects by maintaining the balance between GABAergic and glutamatergic transmission in the basolateral amygdala of ovariectomized mice after stress. | 2013 | Psychoneuroendocrinology | pmid:23669322 |
| Omole F et al. | Easing the burden of premenstrual dysphoric disorder. | 2013 | J Fam Pract | pmid:23326823 |
| Giuliani FA et al. | Allopregnanolone and puberty: modulatory effect on glutamate and GABA release and expression of 3α-hydroxysteroid oxidoreductase in the hypothalamus of female rats. | 2013 | Neuroscience | pmid:23562943 |
| Esser D et al. | Unraveling the function of paralogs of the aldehyde dehydrogenase super family from Sulfolobus solfataricus. | 2013 | Extremophiles | pmid:23296511 |
| Beigi M et al. | TCA cycle involved enzymes SucA and Kgd, as well as MenD: efficient biocatalysts for asymmetric C-C bond formation. | 2013 | Org. Lett. | pmid:23317369 |
| Choi C et al. | A comparative study of short- and long-TE ¹H MRS at 3 T for in vivo detection of 2-hydroxyglutarate in brain tumors. | 2013 | NMR Biomed | pmid:23592268 |
| McNamara RK et al. | Low docosahexaenoic acid status is associated with reduced indices in cortical integrity in the anterior cingulate of healthy male children: a 1H MRS Study. | 2013 | Nutr Neurosci | pmid:23582513 |
| Nizeica V et al. | Bortezomib induced a phrenic palsy in a multiple myeloma patient. | 2013 | Ann. Hematol. | pmid:23370597 |
| Fraccaro E et al. | A study to compare circulating flunixin, meloxicam and gabapentin concentrations with prostaglandin Eâ‚‚ levels in calves undergoing dehorning. | 2013 | Res. Vet. Sci. | pmid:23434065 |
| Hasan A et al. | Epigenetic dysregulation in schizophrenia: molecular and clinical aspects of histone deacetylase inhibitors. | 2013 | Eur Arch Psychiatry Clin Neurosci | pmid:23381549 |
| Kanbayashi Y et al. | Statistical identification of predictors for paclitaxel-induced peripheral neuropathy in patients with breast or gynaecological cancer. | 2013 | Anticancer Res. | pmid:23482795 |
| Arora DS et al. | Hyposensitivity to gamma-aminobutyric acid in the ventral tegmental area during alcohol withdrawal: reversal by histone deacetylase inhibitors. | 2013 | Neuropsychopharmacology | pmid:23474591 |
| Koo J and Zavras A | Antiepileptic drugs (AEDs) during pregnancy and risk of congenital jaw and oral malformation. | 2013 | Oral Dis | pmid:23305414 |
| Shinjyo N et al. | Impact of omega-6 polyunsaturated fatty acid supplementation and γ-aminobutyric acid on astrogliogenesis through the endocannabinoid system. | 2013 | J. Neurosci. Res. | pmid:23633391 |
| Nakane S et al. | Successful treatment of stiff person syndrome with sequential use of tacrolimus. | 2013 | J. Neurol. Neurosurg. Psychiatr. | pmid:23715915 |
| Siebel AM et al. | Antiepileptic drugs prevent changes in adenosine deamination during acute seizure episodes in adult zebrafish. | 2013 | Pharmacol. Biochem. Behav. | pmid:23287800 |
| Bhattarai JP et al. | Genistein excitation of gonadotrophin-releasing hormone neurones in juvenile female mice. | 2013 | J. Neuroendocrinol. | pmid:23351167 |
| Ganguly A and Lee D | Suppression of inhibitory GABAergic transmission by cAMP signaling pathway: alterations in learning and memory mutants. | 2013 | Eur. J. Neurosci. | pmid:23387411 |
| Heo H et al. | Upregulation of TrkB by forskolin facilitated survival of MSC and functional recovery of memory deficient model rats. | 2013 | Biochem. Biophys. Res. Commun. | pmid:23313493 |