4-aminobutyric acid

4-aminobutyric acid is a lipid of Fatty Acyls (FA) class. 4-aminobutyric acid is associated with abnormalities such as Epilepsy and Premenstrual syndrome. The involved functions are known as Binding (Molecular Function), neuron survival, Process, Uptake and physiological aspects. 4-aminobutyric acid often locates in Microglial, Neurofilament, Neuraxis, Brain region and Neurites. The associated genes with 4-aminobutyric acid are arginine methyl ester, SLC33A1 gene, NKS1 gene, P4HTM gene and ITSN2 gene. The related lipids are pregnenolone sulfate, pregnane-20-one, Pregnanes, Steroids and endogenous steroids.

Cross Reference

Introduction

To understand associated biological information of 4-aminobutyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with 4-aminobutyric acid?

4-aminobutyric acid is suspected in Premenstrual syndrome, Epilepsy and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 4-aminobutyric acid

MeSH term MeSH ID Detail
Body Weight D001835 333 associated lipids
Lung Neoplasms D008175 171 associated lipids
Adenocarcinoma D000230 166 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Hemolysis D006461 131 associated lipids
Cell Transformation, Neoplastic D002471 126 associated lipids
Inflammation D007249 119 associated lipids
Hypertension D006973 115 associated lipids
Glioma D005910 112 associated lipids
Weight Gain D015430 101 associated lipids
Insulin Resistance D007333 99 associated lipids
Brain Ischemia D002545 89 associated lipids
Seizures D012640 87 associated lipids
Diabetes Mellitus, Experimental D003921 85 associated lipids
Pancreatic Neoplasms D010190 77 associated lipids
Alzheimer Disease D000544 76 associated lipids
Stomach Ulcer D013276 75 associated lipids
Hyperlipidemias D006949 73 associated lipids
Coronary Disease D003327 70 associated lipids
Reperfusion Injury D015427 65 associated lipids
Pain D010146 64 associated lipids
Weight Loss D015431 56 associated lipids
Diabetes Mellitus, Type 1 D003922 56 associated lipids
Parkinson Disease D010300 53 associated lipids
Nerve Degeneration D009410 53 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Starvation D013217 47 associated lipids
Ischemic Attack, Transient D002546 42 associated lipids
Occupational Diseases D009784 42 associated lipids
Hyperalgesia D006930 42 associated lipids
Arrhythmias, Cardiac D001145 42 associated lipids
Leukemia, Erythroblastic, Acute D004915 41 associated lipids
Arthritis D001168 41 associated lipids
Hypotension D007022 41 associated lipids
Adenoma D000236 40 associated lipids
Diabetic Retinopathy D003930 39 associated lipids
Nervous System Diseases D009422 37 associated lipids
Fever D005334 35 associated lipids
Epilepsy D004827 35 associated lipids
Hyperplasia D006965 34 associated lipids
Spinal Cord Injuries D013119 34 associated lipids
Neurotoxicity Syndromes D020258 34 associated lipids
Memory Disorders D008569 33 associated lipids
Uremia D014511 33 associated lipids
Peripheral Nervous System Diseases D010523 33 associated lipids
Hypothyroidism D007037 32 associated lipids
Drug Eruptions D003875 30 associated lipids
Catalepsy D002375 30 associated lipids
Obesity D009765 29 associated lipids
Kidney Diseases D007674 29 associated lipids
Kidney Neoplasms D007680 29 associated lipids
Adrenoleukodystrophy D000326 29 associated lipids
Insulinoma D007340 28 associated lipids
Neuralgia D009437 28 associated lipids
Brain Diseases D001927 27 associated lipids
Autoimmune Diseases D001327 27 associated lipids
Gastrointestinal Hemorrhage D006471 27 associated lipids
Alcoholism D000437 27 associated lipids
Cerebrovascular Disorders D002561 25 associated lipids
Hyperemia D006940 25 associated lipids
Stomach Neoplasms D013274 24 associated lipids
Arthritis, Experimental D001169 24 associated lipids
Medulloblastoma D008527 22 associated lipids
Hyperglycemia D006943 21 associated lipids
Ataxia D001259 20 associated lipids
Brain Edema D001929 20 associated lipids
Wounds and Injuries D014947 20 associated lipids
Cough D003371 19 associated lipids
Hypothermia D007035 19 associated lipids
Ischemia D007511 18 associated lipids
Down Syndrome D004314 18 associated lipids
Parkinson Disease, Secondary D010302 17 associated lipids
Liver Cirrhosis, Alcoholic D008104 17 associated lipids
Ventricular Fibrillation D014693 16 associated lipids
Hypertrophy D006984 16 associated lipids
Tremor D014202 15 associated lipids
Encephalitis D004660 15 associated lipids
Fetal Resorption D005327 15 associated lipids
Dyskinesia, Drug-Induced D004409 15 associated lipids
Alcoholic Intoxication D000435 15 associated lipids
Reye Syndrome D012202 14 associated lipids
Intellectual Disability D008607 13 associated lipids
Heart Arrest D006323 13 associated lipids
Pain, Postoperative D010149 13 associated lipids
Sarcoma, Experimental D012513 13 associated lipids
Multiple Sclerosis D009103 13 associated lipids
Bradycardia D001919 13 associated lipids
Cerebral Hemorrhage D002543 13 associated lipids
Ketosis D007662 13 associated lipids
Hypocalcemia D006996 12 associated lipids
Death, Sudden D003645 12 associated lipids
Amnesia D000647 12 associated lipids
Retinoblastoma D012175 12 associated lipids
Hyperthyroidism D006980 12 associated lipids
Duodenal Ulcer D004381 12 associated lipids
Hypertension, Portal D006975 12 associated lipids
Migraine Disorders D008881 11 associated lipids
Hyperkinesis D006948 11 associated lipids
Amyotrophic Lateral Sclerosis D000690 11 associated lipids
Exanthema D005076 11 associated lipids
Per page 10 20 50 100 | Total 280

PubChem Associated disorders and diseases

What pathways are associated with 4-aminobutyric acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with 4-aminobutyric acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with 4-aminobutyric acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with 4-aminobutyric acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with 4-aminobutyric acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with 4-aminobutyric acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with 4-aminobutyric acid

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Authors Title Published Journal PubMed Link
Niss AI [Place of neurometabolic stimulators (cerebroprotectors) in the current systematics of psychotropic drugs and their principal kinds of clinical activity]. 1984 Zh Nevropatol Psikhiatr Im S S Korsakova pmid:6464593
Bondarenko TI et al. [Concentration of free amino acids and homocarnosine dipeptide in the cerebrospinal fluid of children with hydrocephalus]. 1983 Zh Nevropatol Psikhiatr Im S S Korsakova pmid:6659780
Tsyganov AI and OzinkovskiÄ­ VV [Effectiveness of the overall treatment of neurosensory hearing disorders using aminalone]. 1977 Nov-Dec Zh Ushn Nos Gorl Bolezn pmid:339592
Lapaev EV et al. [Aminalon as an agent for the prevention of motion sickness]. 1978 Sep-Oct Zh Ushn Nos Gorl Bolezn pmid:360685
IakimovskiÄ­ AF [A comparison of the effects of single and chronic microinjections of GABA and picrotoxin into the caudate nucleus on the conditioned reflexes of dogs]. 1990 May-Jun Zh Vyssh Nerv Deiat Im I P Pavlova pmid:2169148
Talalaenko AN [The role of neurochemical mechanisms of the dorsal raphe nucleus in various models of anxiety states in rats]. 1989 Nov-Dec Zh Vyssh Nerv Deiat Im I P Pavlova pmid:2576490
Norekian TP and Satterly R [A neuronal analysis of the hunting behavior of sea butterfly Clione limacina]. 1991 Sep-Oct Zh Vyssh Nerv Deiat Im I P Pavlova pmid:1662449
Arushanian EB [Stereotyped behavior and the nigro-strio-nigral system]. 1985 Sep-Oct Zh Vyssh Nerv Deiat Im I P Pavlova pmid:2866641
Mukhin EI [Neuropharmacologic analysis of the process of generalization in the cat]. 1986 May-Jun Zh Vyssh Nerv Deiat Im I P Pavlova pmid:2875575
IakimovskiÄ­ AF [Effect of activation and blockade of the GABA-ergic system of the substantia nigra in the midbrain on the realization of conditioned food reflexes in dogs]. 1988 Sep-Oct Zh Vyssh Nerv Deiat Im I P Pavlova pmid:2851896
Belousov AB and Brazhnik ES [The role of GABA-ergic regulation in organizing spontaneous and evoked activity of the septal neurons]. 1988 Nov-Dec Zh Vyssh Nerv Deiat Im I P Pavlova pmid:2854345
Molodavkin GM et al. [Participation of GABA in mediating the effects of ethanol in rats with differing susceptibility to the development of experimental alcoholism]. 1986 May-Jun Zh Vyssh Nerv Deiat Im I P Pavlova pmid:3019039
Kotliar BI and Miasnikov AA [The significance of multiple neuromediator activity in supporting integrative brain functions]. 1988 Sep-Oct Zh Vyssh Nerv Deiat Im I P Pavlova pmid:2906195
RaevskiÄ­ VV [Serotoninergic effects in the early ontogenesis of the cat are effected in the neocortex by inhibitory interneurons]. 1987 Mar-Apr Zh Vyssh Nerv Deiat Im I P Pavlova pmid:3035821
Chizhenkova RA [Effect of GABA on a temporary connection in a neuronal population of the sensorimotor cortex in rabbits]. 1987 Nov-Dec Zh Vyssh Nerv Deiat Im I P Pavlova pmid:3448837
Adrianov OS [Structuro-functional basis of complex forms of higher nervous activity]. 1986 Mar-Apr Zh Vyssh Nerv Deiat Im I P Pavlova pmid:3521135
Shugalev NP and Shiriaev AD [EEG analysis of the effect of stimulation of GABAergic structures of the caudate nucleus on the development of the effect of haloperidol]. 1987 Jan-Feb Zh Vyssh Nerv Deiat Im I P Pavlova pmid:3577401
Saul'skaia NB [Dopamine metabolism and the GABA level in the structures of the nigrostriatal and mesolimbic systems of the rat brain in experimental pathology of higher nervous activity]. 1988 Nov-Dec Zh Vyssh Nerv Deiat Im I P Pavlova pmid:3245325
Aftanas LI and Il'iuchenok RIu [Strengthening interhemispheric interferential inhibition in man with diazepam]. 1986 Jul-Aug Zh Vyssh Nerv Deiat Im I P Pavlova pmid:3020832
Shul'gina GI et al. [Effect of a derivative of GABA, phenibut, on behavior and the activity of visual cortex neurons of the rabbit during elaboration of a defensive reflex and internal inhibition]. 1985 Jul-Aug Zh Vyssh Nerv Deiat Im I P Pavlova pmid:4050110
Talalaenko AN [Neurochemical mechanisms of septal influence on the conditioned avoidance reaction in rats]. 1974 Jul-Aug Zh Vyssh Nerv Deiat Im I P Pavlova pmid:4155847
Uryvaev IuV and Chuppina LM [The influence of the frontal region on evoked potentials in the visual cortex of dogs]. 1974 Jul-Aug Zh Vyssh Nerv Deiat Im I P Pavlova pmid:4155849
Karpova IV [The content of dopamine, its metabolites and GABA in the nigrostriatal system of rats with different learning abilities]. 1992 Jan-Feb Zh Vyssh Nerv Deiat Im I P Pavlova pmid:1316006
Karpova IV [The effect of ethanol on the motor activity of rats and on the content of GABA and dopamine and its metabolites in the nigrostriatal system]. 1992 Sep-Oct Zh Vyssh Nerv Deiat Im I P Pavlova pmid:1336265
Beneshova O [Genetically determined variability in rat behavior and its biochemical correlates]. 1978 Mar-Apr Zh Vyssh Nerv Deiat Im I P Pavlova pmid:565997
Pavlygina RA [Role of the inhibitory process in closing a simple form of temporary connection]. 1978 May-Jun Zh Vyssh Nerv Deiat Im I P Pavlova pmid:676498
Talalaenko AN and Krivobok GK [Differences in hypothalamic monoaminergic mechanisms in heterogeneous conditioned reflexes in rats]. 1979 Nov-Dec Zh Vyssh Nerv Deiat Im I P Pavlova pmid:532342
Adrianov OS et al. [The effect of neurotropic agents on evoked potentials of the association and projection regions of the cat neocortex]. 1975 Sep-Oct Zh Vyssh Nerv Deiat Im I P Pavlova pmid:1210745
Bezdenezhnykh BN [Neurochemical study of phasic responses of a neuron to conditioned and unconditioned stimuli]. 1977 Jan-Feb Zh Vyssh Nerv Deiat Im I P Pavlova pmid:855483
RaevskiÄ­ VV [Formation of serotonin- and GABA-ergic mechanisms of synaptic transmission in the cat neocortex during early ontogenesis]. 1987 Jul-Aug Zh Vyssh Nerv Deiat Im I P Pavlova pmid:2823502
Aleksandrov AA et al. [Inhibitory responses of sensomotor cortex neurons in the rabbit to the initial stages of elaboration of conditioned defensive reflexes]. 1983 Jul-Aug Zh Vyssh Nerv Deiat Im I P Pavlova pmid:6137917
Shabanov PD [Reproduction of "passive" avoidance in rats by administering pharmacologic agents]. 1981 Jan-Feb Zh Vyssh Nerv Deiat Im I P Pavlova pmid:6113722
Shvets-Teneta-Gurií TB [Steady potential level following application of gamma-aminobutyric acid to the surface of the brain]. 1981 Sep-Oct Zh Vyssh Nerv Deiat Im I P Pavlova pmid:6118982
IakimovskiÄ­ AF [The effect of multiple administrations of GABA and bicuculline into the rat neostriatum on the realization of a food-acquisition habit]. 1996 May-Jun Zh Vyssh Nerv Deiat Im I P Pavlova pmid:8755055
Mukhin EI [Neuropharmacologic analysis of the dopamin-, cholin- and GABA-ergic systems of the brain in the organization of reflexes to time]. 1984 Jul-Aug Zh Vyssh Nerv Deiat Im I P Pavlova pmid:6149658
Andreev BV et al. [Anti-stress role of the GABA-ergic system of the brain]. 1982 May-Jun Zh Vyssh Nerv Deiat Im I P Pavlova pmid:7202308
Malakhovskaia DB and Sviderskaia GE [Effect of GABA on motor activity in the rat during the early postnatal period]. 1982 Jan-Feb Zh Vyssh Nerv Deiat Im I P Pavlova pmid:7064553
Riabinskaia EA and Gabibov IM [Effect of gamma-aminobutyric acid on audiogenic seizures and conditioned reflexes in the rat]. 1982 Jan-Feb Zh Vyssh Nerv Deiat Im I P Pavlova pmid:7064567
Zhadina SD et al. [Effect of electric stimulation of afferent pathways on neurons in septal sections]. 1982 May-Jun Zh Vyssh Nerv Deiat Im I P Pavlova pmid:7113454
Godukhin OV [Analysis of thalamo-striate interrelationships]. 1980 Mar-Apr Zh Vyssh Nerv Deiat Im I P Pavlova pmid:7386043
Talalaenko AN et al. [Pharmacologic analysis of monoaminergic mechanisms of the medial hypothalamus in food-getting conditioned reflexes in rats]. 1980 Nov-Dec Zh Vyssh Nerv Deiat Im I P Pavlova pmid:7467841
Aleksandrov AA et al. [Effect of microelectrophoretic application of GABA on the formation of a cellular analog of a conditioned reaction]. 1984 Nov-Dec Zh Vyssh Nerv Deiat Im I P Pavlova pmid:6524071
Shugalev NP [Effect of stimulation of GABA-ergic structures of the substantia nigra and caudate nucleus on food-getting behavior in the cat]. 1983 May-Jun Zh Vyssh Nerv Deiat Im I P Pavlova pmid:6613342
Mekhedova AIa [Comparative evaluation of the effects of piracetam and aminalone in experimental neuroses in the dog]. 1983 Sep-Oct Zh Vyssh Nerv Deiat Im I P Pavlova pmid:6685954
Batuev AS et al. [Audiogenic epilepsy: a morphofunctional analysis]. 1997 Mar-Apr Zh Vyssh Nerv Deiat Im I P Pavlova pmid:9173746
Murzina GB and Sil'kis IG [Long-term potentiation and depression of inhibitory transmission studied by using mathematical modelling of the postsynaptic processes]. 1996 Sep-Oct Zh Vyssh Nerv Deiat Im I P Pavlova pmid:9054144
Kratskin IL et al. [GABA immunoreactivity in the main olfactory bulb of the frog Rana temporaria]. 1989 Jan-Feb Zh. Evol. Biokhim. Fiziol. pmid:2658429
Kenigfest NB et al. [GABA-immunoreactive cells in the brain of the frog Rana temporaria]. 1989 Jan-Feb Zh. Evol. Biokhim. Fiziol. pmid:2786301
AÄ­rapetian SN and Carpenter DO [The modulatory action of superlow doses of mediators on the functional activity of the neuronal membrane]. 1991 Mar-Apr Zh. Evol. Biokhim. Fiziol. pmid:1681636
KozlovskiÄ­ VL [Pharmacological analysis of the ontogenetic traits of the functional receptor activity of glial and neuronal GABA uptake and GABA-T activity in the rat hippocampus]. 1986 Nov-Dec Zh. Evol. Biokhim. Fiziol. pmid:3030028