4-aminobutyric acid is a lipid of Fatty Acyls (FA) class. 4-aminobutyric acid is associated with abnormalities such as Epilepsy and Premenstrual syndrome. The involved functions are known as Binding (Molecular Function), neuron survival, Process, Uptake and physiological aspects. 4-aminobutyric acid often locates in Microglial, Neurofilament, Neuraxis, Brain region and Neurites. The associated genes with 4-aminobutyric acid are arginine methyl ester, SLC33A1 gene, NKS1 gene, P4HTM gene and ITSN2 gene. The related lipids are pregnenolone sulfate, pregnane-20-one, Pregnanes, Steroids and endogenous steroids.
To understand associated biological information of 4-aminobutyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
4-aminobutyric acid is suspected in Premenstrual syndrome, Epilepsy and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with 4-aminobutyric acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Arias P et al. | Changes in mediobasal hypothalamic dopamine and GABA release: a possible mechanism underlying taurine-induced prolactin secretion. | 1998 | Amino Acids | pmid:9871483 |
Ruotsalainen M et al. | Locally infused taurine, GABA and homotaurine alter differently the striatal extracellular concentrations of dopamine and its metabolites in rats. | 1998 | Amino Acids | pmid:9871492 |
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Osborne JP et al. | Infantile spasms and vigabatrin. Study will compare effects of drugs. | 1999 | BMJ | pmid:9872899 |
Bernstein EM and Quick MW | Regulation of gamma-aminobutyric acid (GABA) transporters by extracellular GABA. | 1999 | J. Biol. Chem. | pmid:9873028 |
Serfass L and Casara PJ | General synthesis of 3-substituted alkenyl GABA as potential anticonvulsants. | 1998 | Bioorg. Med. Chem. Lett. | pmid:9873588 |