4-aminobutyric acid is a lipid of Fatty Acyls (FA) class. 4-aminobutyric acid is associated with abnormalities such as Epilepsy and Premenstrual syndrome. The involved functions are known as Binding (Molecular Function), neuron survival, Process, Uptake and physiological aspects. 4-aminobutyric acid often locates in Microglial, Neurofilament, Neuraxis, Brain region and Neurites. The associated genes with 4-aminobutyric acid are arginine methyl ester, SLC33A1 gene, NKS1 gene, P4HTM gene and ITSN2 gene. The related lipids are pregnenolone sulfate, pregnane-20-one, Pregnanes, Steroids and endogenous steroids.
To understand associated biological information of 4-aminobutyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
4-aminobutyric acid is suspected in Premenstrual syndrome, Epilepsy and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with 4-aminobutyric acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
Lipid concept | Cross reference | Weighted score | Related literatures |
---|
Gene | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
pmid:9779447 | ||||
pmid:9779444 | ||||
pmid:9778609 | ||||
pmid:9778608 | ||||
pmid:9778601 | ||||
pmid:9778599 | ||||
pmid:9778575 | ||||
pmid:9778572 | ||||
pmid:9778567 | ||||
pmid:9778244 | ||||
Murugaiah KD and Hemmings HC | Effects of intravenous general anesthetics on [3H]GABA release from rat cortical synaptosomes. | 1998 | Anesthesiology | pmid:9778010 |
Ronquist G et al. | Alpha-aminoisobutyric acid transport into human glia and glioma cells in culture. | 1976 | J. Cell. Physiol. | pmid:977662 |
Mongeau R et al. | Effect of acute, short- and long-term milnacipran administration on rat locus coeruleus noradrenergic and dorsal raphe serotonergic neurons. | 1998 | Neuropharmacology | pmid:9776386 |
Williamson AV et al. | Properties of GABA(A) receptors in cultured rat oligodendrocyte progenitor cells. | 1998 | Neuropharmacology | pmid:9776382 |
Tomasini MC and Antonelli T | Electrically evoked [3H]GABA release from cerebral cortical cultures: an in vitro approach for studying glutamate-induced neurotoxicity. | 1998 | Synapse | pmid:9776128 |
Bakardjiev A | Carnosine and beta-alanine release is stimulated by glutamatergic receptors in cultured rat oligodendrocytes. | 1998 | Glia | pmid:9775986 |
Podell M | Antiepileptic drug therapy. | 1998 | Clin Tech Small Anim Pract | pmid:9775509 |
March PA | Seizures: classification, etiologies, and pathophysiology. | 1998 | Clin Tech Small Anim Pract | pmid:9775502 |
Fadda F and Rossetti ZL | Chronic ethanol consumption: from neuroadaptation to neurodegeneration. | 1998 | Prog. Neurobiol. | pmid:9775400 |
Garaizar C et al. | [Therapeutic failure, treatment and non-treatment of childhood epilepsy]. | 1998 | Rev Neurol | pmid:9774821 |
Murphy SM et al. | Pre-embedding staining for GAD67 versus postembedding staining for GABA as markers for central GABAergic terminals. | 1998 | J. Histochem. Cytochem. | pmid:9774625 |
Ferraro L et al. | The effects of modafinil on striatal, pallidal and nigral GABA and glutamate release in the conscious rat: evidence for a preferential inhibition of striato-pallidal GABA transmission. | 1998 | Neurosci. Lett. | pmid:9774168 |
Tate AK and Malpeli JG | Effects of focal inactivation of dorsal or ventral layers of the lateral geniculate nucleus on cats' ability to see and fixate small targets. | 1998 | J. Neurophysiol. | pmid:9772272 |
Gao F and Wu SM | Characterization of spontaneous inhibitory synaptic currents in salamander retinal ganglion cells. | 1998 | J. Neurophysiol. | pmid:9772236 |
Kapur A and Haberly LB | Duration of NMDA-dependent synaptic potentiation in piriform cortex in vivo is increased after epileptiform bursting. | 1998 | J. Neurophysiol. | pmid:9772226 |
Fernández A et al. | The marginal nuclei of the spinal cord in turtles: neuron assemblies in which gamma-aminobutyric acid and nitric oxide synthase are colocalized. | 1998 | Exp Brain Res | pmid:9772120 |
Corá-Locatelli G et al. | Gabapentin augmentation for fluoxetine-treated patients with obsessive-compulsive disorder. | 1998 | J Clin Psychiatry | pmid:9771822 |
Schwartzkroin PA | GABA synapses enter the molecular big time. | 1998 | Nat. Med. | pmid:9771735 |
Scott RC et al. | Status epilepticus: pathophysiology, epidemiology, and outcomes. | 1998 | Arch. Dis. Child. | pmid:9771258 |
De Luka SR et al. | [Gamma aminobutyric acid--its function, disorders and their sequelae]. | 1998 Jul-Aug | Med. Pregl. | pmid:9769665 |
Mienville JM | Persistent depolarizing action of GABA in rat Cajal-Retzius cells. | 1998 | J. Physiol. (Lond.) | pmid:9769423 |
Engel D et al. | Laminar difference in GABA uptake and GAT-1 expression in rat CA1. | 1998 | J. Physiol. (Lond.) | pmid:9769410 |
Shiah IS and Yatham LN | GABA function in mood disorders: an update and critical review. | 1998 | Life Sci. | pmid:9768867 |
Rutherford LC et al. | BDNF has opposite effects on the quantal amplitude of pyramidal neuron and interneuron excitatory synapses. | 1998 | Neuron | pmid:9768839 |
Santos PF et al. | Differential acetylcholine and GABA release from cultured chick retina cells. | 1998 | Eur. J. Neurosci. | pmid:9767402 |
Avoli M et al. | GABA-dependent generation of ectopic action potentials in the rat hippocampus. | 1998 | Eur. J. Neurosci. | pmid:9767401 |
Tunnicliff G | Centrally-acting drugs and the formation of brain gamma-aminobutyric acid. | 1976 | Gen. Pharmacol. | pmid:976740 |
Ballanyi K and Kulik A | Intracellular Ca2+ during metabolic activation of KATP channels in spontaneously active dorsal vagal neurons in medullary slices. | 1998 | Eur. J. Neurosci. | pmid:9767388 |
Vinay L et al. | Spinal inputs from lateral columns to reticulospinal neurons in lampreys. | 1998 | Brain Res. | pmid:9767174 |
Goebel DJ et al. | Immunocytochemical localization of the NMDA-R2A receptor subunit in the cat retina. | 1998 | Brain Res. | pmid:9767152 |
Sorkin LS et al. | Spinal bicuculline produces hypersensitivity of dorsal horn neurons: effects of excitatory amino acid antagonists. | 1998 | Pain | pmid:9766836 |
Guthmann A et al. | GABA, GABA transporters, GABA(A) receptor subunits, and GAD mRNAs in the rat parabrachial and Kölliker-Fuse nuclei. | 1998 | J. Comp. Neurol. | pmid:9766401 |
Van Bockstaele EJ | Morphological substrates underlying opioid, epinephrine and gamma-aminobutyric acid inhibitory actions in the rat locus coeruleus. | 1998 | Brain Res. Bull. | pmid:9766384 |
Giorgetti M et al. | Imidazenil, a positive allosteric GABAA receptor modulator, inhibits the effects of cocaine on locomotor activity and extracellular dopamine in the nucleus accumbens shell without tolerance liability. | 1998 | J. Pharmacol. Exp. Ther. | pmid:9765322 |
pmid:9764858 | ||||
pmid:9764538 | ||||
Logan WJ | Amino acid transport by two glial cell lines and by proliferating glia. | 1976 | Exp. Neurol. | pmid:976410 |
Orr HT et al. | The levels of free taurine, glutamate, glycine and gamma-amino butyric acid during the postnatal development of the normal and dystrophic retina of the mouse. | 1976 | Exp. Eye Res. | pmid:976379 |
pmid:9763645 | ||||
pmid:9763621 |