4-aminobutyric acid
4-aminobutyric acid is a lipid of Fatty Acyls (FA) class. 4-aminobutyric acid is associated with abnormalities such as Epilepsy and Premenstrual syndrome. The involved functions are known as Binding (Molecular Function), neuron survival, Process, Uptake and physiological aspects. 4-aminobutyric acid often locates in Microglial, Neurofilament, Neuraxis, Brain region and Neurites. The associated genes with 4-aminobutyric acid are arginine methyl ester, SLC33A1 gene, NKS1 gene, P4HTM gene and ITSN2 gene. The related lipids are pregnenolone sulfate, pregnane-20-one, Pregnanes, Steroids and endogenous steroids.
Cross Reference
Introduction
To understand associated biological information of 4-aminobutyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with 4-aminobutyric acid?
4-aminobutyric acid is suspected in Premenstrual syndrome, Epilepsy and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with 4-aminobutyric acid
PubChem Associated disorders and diseases
What pathways are associated with 4-aminobutyric acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with 4-aminobutyric acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with 4-aminobutyric acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with 4-aminobutyric acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with 4-aminobutyric acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with 4-aminobutyric acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with 4-aminobutyric acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Wang C et al. | Succinic Semialdehyde Promotes Prosurvival Capability of Agrobacterium tumefaciens. | 2016 | J. Bacteriol. | pmid:26755630 |
| Åžavk E | Neurologic Itch Management. | 2016 | Curr. Probl. Dermatol. | pmid:27578080 |
| Simm B et al. | Effects of prostaglandin E2 on cells cultured from the rat organum vasculosum laminae terminalis and median preoptic nucleus. | 2016 | Neuroscience | pmid:26608124 |
| Ikarashi Y and Mizoguchi K | Neuropharmacological efficacy of the traditional Japanese Kampo medicine yokukansan and its active ingredients. | 2016 | Pharmacol. Ther. | pmid:27373856 |
| Chinnici F et al. | Discrimination of some European vinegars with protected denomination of origin as a function of their amino acid and biogenic amine content. | 2016 | J. Sci. Food Agric. | pmid:26676828 |
| Wongsamitkul N et al. | Toward Understanding Functional Properties and Subunit Arrangement of α4β2δ γ-Aminobutyric Acid, Type A (GABAA) Receptors. | 2016 | J. Biol. Chem. | pmid:27382064 |
| Deligiannidis KM et al. | Peripartum neuroactive steroid and γ-aminobutyric acid profiles in women at-risk for postpartum depression. | 2016 | Psychoneuroendocrinology | pmid:27209438 |
| Olexová L et al. | Increased anxiety-like behaviour and altered GABAergic system in the amygdala and cerebellum of VPA rats - An animal model of autism. | 2016 | Neurosci. Lett. | pmid:27353514 |
| Martin BS et al. | Rescue of deficient amygdala tonic γ-aminobutyric acidergic currents in the Fmr-/y mouse model of fragile X syndrome by a novel γ-aminobutyric acid type A receptor-positive allosteric modulator. | 2016 | J. Neurosci. Res. | pmid:26308557 |
| Wang L et al. | Metabolic Responses of Poplar to Apripona germari (Hope) as Revealed by Metabolite Profiling. | 2016 | Int J Mol Sci | pmid:27331808 |
| Aseervatham GS et al. | Expression pattern of NMDA receptors reveals antiepileptic potential of apigenin 8-C-glucoside and chlorogenic acid in pilocarpine induced epileptic mice. | 2016 | Biomed. Pharmacother. | pmid:27470339 |
| Piplani S et al. | Neuroinformatics analyses reveal GABAt and SSADH as major proteins involved in anticonvulsant activity of valproic acid. | 2016 | Biomed. Pharmacother. | pmid:27261619 |
| Vazquez-DeRose J et al. | Hypocretin/orexin antagonism enhances sleep-related adenosine and GABA neurotransmission in rat basal forebrain. | 2016 | Brain Struct Funct | pmid:25431268 |
| Tessarin P et al. | Influence of canopy-applied chitosan on the composition of organic cv. Sangiovese and Cabernet Sauvignon berries and wines. | 2016 | Food Chem | pmid:27211677 |
| Buczynski MW et al. | Diacylglycerol lipase disinhibits VTA dopamine neurons during chronic nicotine exposure. | 2016 | Proc. Natl. Acad. Sci. U.S.A. | pmid:26755579 |
| Vanya M et al. | [Preconceptional and perinatal challenges of pregnancy in women with epilepsy]. | 2016 | Orv Hetil | pmid:27039994 |
| Volk DW and Lewis DA | The Role of Endocannabinoid Signaling in Cortical Inhibitory Neuron Dysfunction in Schizophrenia. | 2016 | Biol. Psychiatry | pmid:26210060 |
| Xie M et al. | Gastroprotective effect of gamma-aminobutyric acid against ethanol-induced gastric mucosal injury. | 2017 | Chem. Biol. Interact. | pmid:28456544 |
| Khongrum J and Wattanathorn J | Laser Acupuncture at HT7 Improves the Cerebellar Disorders in Valproic Acid-Rat Model of Autism. | 2017 | J Acupunct Meridian Stud | pmid:28889839 |
| Androsova G et al. | Comparative effectiveness of antiepileptic drugs in patients with mesial temporal lobe epilepsy with hippocampal sclerosis. | 2017 | Epilepsia | pmid:28857179 |