4-aminobutyric acid

4-aminobutyric acid is a lipid of Fatty Acyls (FA) class. 4-aminobutyric acid is associated with abnormalities such as Epilepsy and Premenstrual syndrome. The involved functions are known as Binding (Molecular Function), neuron survival, Process, Uptake and physiological aspects. 4-aminobutyric acid often locates in Microglial, Neurofilament, Neuraxis, Brain region and Neurites. The associated genes with 4-aminobutyric acid are arginine methyl ester, SLC33A1 gene, NKS1 gene, P4HTM gene and ITSN2 gene. The related lipids are pregnenolone sulfate, pregnane-20-one, Pregnanes, Steroids and endogenous steroids.

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Introduction

To understand associated biological information of 4-aminobutyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with 4-aminobutyric acid?

4-aminobutyric acid is suspected in Premenstrual syndrome, Epilepsy and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 4-aminobutyric acid

MeSH term MeSH ID Detail
Fetal Alcohol Spectrum Disorders D063647 6 associated lipids
Genetic Diseases, Inborn D030342 4 associated lipids
Vitamin B 6 Deficiency D026681 10 associated lipids
Hyperammonemia D022124 5 associated lipids
Embryo Loss D020964 5 associated lipids
Paraparesis D020335 1 associated lipids
Neurotoxicity Syndromes D020258 34 associated lipids
Serotonin Syndrome D020230 1 associated lipids
Epilepsy, Reflex D020195 5 associated lipids
Gangliosidoses, GM2 D020143 1 associated lipids
Cocaine-Related Disorders D019970 3 associated lipids
Hemifacial Spasm D019569 1 associated lipids
Neck Pain D019547 2 associated lipids
Gingival Overgrowth D019214 7 associated lipids
Neuroaxonal Dystrophies D019150 3 associated lipids
Congenital Disorders of Glycosylation D018981 1 associated lipids
Encephalitis, Viral D018792 3 associated lipids
Tension-Type Headache D018781 1 associated lipids
Hypokinesia D018476 2 associated lipids
Neuroendocrine Tumors D018358 4 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with 4-aminobutyric acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with 4-aminobutyric acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with 4-aminobutyric acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with 4-aminobutyric acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with 4-aminobutyric acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with 4-aminobutyric acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with 4-aminobutyric acid

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Authors Title Published Journal PubMed Link
Karaseva TL et al. [Gamma-aminobutyric acid metabolism in the rat brain after administration of nootropic agents]. 1988 May-Jun Vopr. Med. Khim. pmid:2971290
Kanunnikova NP and Koval'chuk VG [Characteristics of dopamine and GABA system functions in the brain of animals with different durations of ethanol sleep]. 1986 May-Jun Vopr. Med. Khim. pmid:3727469
Goroshinskaia IA et al. [Monoamine oxidase activity and gamma-aminobutyric acid levels in hyperoxia. The effect of clorgyline]. 1986 Mar-Apr Vopr. Med. Khim. pmid:3705520
Rozanov VA et al. [Effect of repeated injections of GABA on the GABA shunt and various associated reactions in the rat brain]. 1988 Jan-Feb Vopr. Med. Khim. pmid:3369124
Faradzhev AN [The effect of starvation on GABA-transaminase and glutamate decarboxylase activity on mitochondria of dog limbic structures during postnatal ontogenesis]. 1988 Nov-Dec Vopr. Med. Khim. pmid:3238940
Maslova IV et al. [Metabolism of acetylcholine and gamma-aminobutyric acid in the basal ganglia and limbic cortex of rats at different stages in the development of alcohol dependence]. 1986 Jan-Feb Vopr. Med. Khim. pmid:3953003
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Promyslov MSh and Solov'eva TV [Effect of intravenous administration of gamma-hydroxybutyric and succinic acids on the metabolism of gamma-aminobutyric acid in the brain]. 1973 Vopr. Med. Khim. pmid:4153200
Emirbekov EZ and L'vova SP [Nitrogen and carbohydrate-phosphate metabolism in the brain of warm-blooded animals during hypothermia and hibernation]. 1972 Vopr. Med. Khim. pmid:4153228
Galoian AA et al. [Significance of cholinoreactive substances in the brain in the formation and transport of hormones regulating coronary vessel tone]. 1972 Vopr. Med. Khim. pmid:4153240
Khizhniakova TM et al. [Gamma-aminobutyric acid concentration in the brains of animals infected with fixed rabies virus]. 1974 Nov-Dec Vopr. Med. Khim. pmid:4155823
Kunert E and Dovedova EL [Effect of light deprivation on GABA metabolism in subcellular fractions of the rabbit visual system]. 1979 Jul-Aug Vopr. Med. Khim. pmid:473689
Pigareva ZD et al. [Effect of early visual deprivation on the free amino acid and protein content in the brain formations of dogs]. 1976 Mar-Apr Vopr. Med. Khim. pmid:1030888
Veksler IaI et al. [Characteristics of the central nervous system metabolism reaction to stress in acute alcoholic intoxication]. 1978 Mar-Apr Vopr. Med. Khim. pmid:566485
Promyslov MSh and Kapytovskaia IN [Several methodolic features of determining cerebral gamma-aminobutyric acid]. 1977 Jan-Feb Vopr. Med. Khim. pmid:855227
Moskvitina TA et al. [Changes in substrate specificity of brain mitochondrial monoamine oxidase]. 1977 May-Jun Vopr. Med. Khim. pmid:888399
Krichevskaia AA et al. [Content of gamma-aminobutyric acid and glutamate decarboxylase activity in the rat brain during hyperbaric oxygenation and the protective action of urea]. 1974 Vopr. Med. Khim. pmid:4836787
Buniatian GKh et al. [Effect of gamma-aminobutyric acid on formation of tyrosine from L-phenylalanine in brain and liver tissues]. 1971 Jan-Feb Vopr. Med. Khim. pmid:5555148
RaÄ­gorodskaia DI et al. [Change in the catalytic properties of mitochondrial monoamine oxidase in experimental audiogenic epilepsy]. 1991 Mar-Apr Vopr. Med. Khim. pmid:1897194