4-aminobutyric acid

4-aminobutyric acid is a lipid of Fatty Acyls (FA) class. 4-aminobutyric acid is associated with abnormalities such as Epilepsy and Premenstrual syndrome. The involved functions are known as Binding (Molecular Function), neuron survival, Process, Uptake and physiological aspects. 4-aminobutyric acid often locates in Microglial, Neurofilament, Neuraxis, Brain region and Neurites. The associated genes with 4-aminobutyric acid are arginine methyl ester, SLC33A1 gene, NKS1 gene, P4HTM gene and ITSN2 gene. The related lipids are pregnenolone sulfate, pregnane-20-one, Pregnanes, Steroids and endogenous steroids.

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Introduction

To understand associated biological information of 4-aminobutyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with 4-aminobutyric acid?

4-aminobutyric acid is suspected in Premenstrual syndrome, Epilepsy and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 4-aminobutyric acid

MeSH term MeSH ID Detail
Fetal Alcohol Spectrum Disorders D063647 6 associated lipids
Genetic Diseases, Inborn D030342 4 associated lipids
Vitamin B 6 Deficiency D026681 10 associated lipids
Hyperammonemia D022124 5 associated lipids
Embryo Loss D020964 5 associated lipids
Paraparesis D020335 1 associated lipids
Neurotoxicity Syndromes D020258 34 associated lipids
Serotonin Syndrome D020230 1 associated lipids
Epilepsy, Reflex D020195 5 associated lipids
Gangliosidoses, GM2 D020143 1 associated lipids
Cocaine-Related Disorders D019970 3 associated lipids
Hemifacial Spasm D019569 1 associated lipids
Neck Pain D019547 2 associated lipids
Gingival Overgrowth D019214 7 associated lipids
Neuroaxonal Dystrophies D019150 3 associated lipids
Congenital Disorders of Glycosylation D018981 1 associated lipids
Encephalitis, Viral D018792 3 associated lipids
Tension-Type Headache D018781 1 associated lipids
Hypokinesia D018476 2 associated lipids
Neuroendocrine Tumors D018358 4 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with 4-aminobutyric acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with 4-aminobutyric acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with 4-aminobutyric acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with 4-aminobutyric acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with 4-aminobutyric acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with 4-aminobutyric acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with 4-aminobutyric acid

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Authors Title Published Journal PubMed Link
Terasawa E et al. An increase in glutamate release follows a decrease in gamma aminobutyric acid and the pubertal increase in luteinizing hormone releasing hormone release in the female rhesus monkeys. 1999 J. Neuroendocrinol. pmid:10223281
Gonzalo-Ruiz A et al. Localization of amino acids, neuropeptides and cholinergic neurotransmitter markers in identified projections from the mesencephalic tegmentum to the mammillary nuclei of the rat. 1999 J. Chem. Neuroanat. pmid:10223311
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Podell M and Hadjiconstantinou M Low concentrations of cerebrospinal fluid GABA correlate to a reduced response to phenobarbital therapy in primary canine epilepsy. 1999 Mar-Apr J. Vet. Intern. Med. pmid:10225597
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Colado MI et al. Studies on the neuroprotective effect of pentobarbitone on MDMA-induced neurodegeneration. 1999 Psychopharmacology (Berl.) pmid:10229068
Pollák E et al. Localization and source of gamma aminobutyric acid immunoreactivity in the isthmic nucleus of the frog Rana esculenta. 1999 Brain Res. Bull. pmid:10229344
Caviedes BE et al. [In children with refractory epilepsy: vigabatrin or lamotrigine?]. 1999 Mar 1-15 Rev Neurol pmid:10229954
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Calogero AE et al. Gamma-aminobutyric acid (GABA) A and B receptors mediate the stimulatory effects of GABA on the human sperm acrosome reaction: interaction with progesterone. 1999 Fertil. Steril. pmid:10231059
Parsons LH et al. RU 24969, a 5-HT1B/1A receptor agonist, potentiates cocaine-induced increases in nucleus accumbens dopamine. 1999 Synapse pmid:10231132
Rocha L et al. Gabapentin modifies extracellular opioid peptide content in amygdala: a microdialysis study. 1999 Epilepsy Res. pmid:10232790
Gobbi G et al. Prospective study of first-line vigabatrin monotherapy in childhood partial epilepsies. 1999 Epilepsy Res. pmid:10232792