4-aminobutyric acid

4-aminobutyric acid is a lipid of Fatty Acyls (FA) class. 4-aminobutyric acid is associated with abnormalities such as Epilepsy and Premenstrual syndrome. The involved functions are known as Binding (Molecular Function), neuron survival, Process, Uptake and physiological aspects. 4-aminobutyric acid often locates in Microglial, Neurofilament, Neuraxis, Brain region and Neurites. The associated genes with 4-aminobutyric acid are arginine methyl ester, SLC33A1 gene, NKS1 gene, P4HTM gene and ITSN2 gene. The related lipids are pregnenolone sulfate, pregnane-20-one, Pregnanes, Steroids and endogenous steroids.

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Introduction

To understand associated biological information of 4-aminobutyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with 4-aminobutyric acid?

4-aminobutyric acid is suspected in Premenstrual syndrome, Epilepsy and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 4-aminobutyric acid

MeSH term MeSH ID Detail
Fetal Alcohol Spectrum Disorders D063647 6 associated lipids
Genetic Diseases, Inborn D030342 4 associated lipids
Vitamin B 6 Deficiency D026681 10 associated lipids
Hyperammonemia D022124 5 associated lipids
Embryo Loss D020964 5 associated lipids
Paraparesis D020335 1 associated lipids
Neurotoxicity Syndromes D020258 34 associated lipids
Serotonin Syndrome D020230 1 associated lipids
Epilepsy, Reflex D020195 5 associated lipids
Gangliosidoses, GM2 D020143 1 associated lipids
Cocaine-Related Disorders D019970 3 associated lipids
Hemifacial Spasm D019569 1 associated lipids
Neck Pain D019547 2 associated lipids
Gingival Overgrowth D019214 7 associated lipids
Neuroaxonal Dystrophies D019150 3 associated lipids
Congenital Disorders of Glycosylation D018981 1 associated lipids
Encephalitis, Viral D018792 3 associated lipids
Tension-Type Headache D018781 1 associated lipids
Hypokinesia D018476 2 associated lipids
Neuroendocrine Tumors D018358 4 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with 4-aminobutyric acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with 4-aminobutyric acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with 4-aminobutyric acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with 4-aminobutyric acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with 4-aminobutyric acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with 4-aminobutyric acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with 4-aminobutyric acid

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Authors Title Published Journal PubMed Link
Scharfman HE and MacLusky NJ Differential regulation of BDNF, synaptic plasticity and sprouting in the hippocampal mossy fiber pathway of male and female rats. 2014 Neuropharmacology pmid:23660230
Vashchinkina E et al. Neurosteroid Agonist at GABAA receptor induces persistent neuroplasticity in VTA dopamine neurons. 2014 Neuropsychopharmacology pmid:24077066
Mango D et al. Phosphodiesterase 10A controls D1-mediated facilitation of GABA release from striato-nigral projections under normal and dopamine-depleted conditions. 2014 Neuropharmacology pmid:23973317
Chou HT et al. Functional characterization of the agtABCD and agtSR operons for 4-aminobutyrate and 5-aminovalerate uptake and regulation in Pseudomonas aeruginosa PAO1. 2014 Curr. Microbiol. pmid:23982201
Kumar A et al. Hesperidin potentiates the neuroprotective effects of diazepam and gabapentin against pentylenetetrazole-induced convulsions in mice: Possible behavioral, biochemical and mitochondrial alterations. 2014 May-Jun Indian J Pharmacol pmid:24987179
Rizk NN et al. Use of topical lidocaine, diphenhydramine hydrochloride, nystatin, and gabapentin swish in treatment for post-radiation neuropathy and oral mucositis. 2014 May-Jun Pain Physician pmid:24850125
Tao W et al. Brainstem brain-derived neurotrophic factor signaling is required for histone deacetylase inhibitor-induced pain relief. 2015 Mol. Pharmacol. pmid:25852071
Trotti LM et al. Clarithromycin in γ-aminobutyric acid-Related hypersomnolence: A randomized, crossover trial. 2015 Ann. Neurol. pmid:26094838
Zhao W et al. A study on quality components and sleep-promoting effects of GABA black tea. 2015 Food Funct pmid:26290415
Bönnighausen J et al. Disruption of the GABA shunt affects mitochondrial respiration and virulence in the cereal pathogen Fusarium graminearum. 2015 Mol. Microbiol. pmid:26305050
Mirabella R et al. WRKY40 and WRKY6 act downstream of the green leaf volatile E-2-hexenal in Arabidopsis. 2015 Plant J. pmid:26243404
Groundwater PW et al. The Differential Effects of Resveratrol and trans-ε-Viniferin on the GABA-Induced Current in GABAA Receptor Subtypes Expressed in Xenopus Laevis Oocytes. 2015 J Pharm Pharm Sci pmid:26626239
Lee KH et al. Bidirectional Signaling of Neuregulin-2 Mediates Formation of GABAergic Synapses and Maturation of Glutamatergic Synapses in Newborn Granule Cells of Postnatal Hippocampus. 2015 J. Neurosci. pmid:26674872
Sikoglu EM et al. Vitamin D3 Supplemental Treatment for Mania in Youth with Bipolar Spectrum Disorders. 2015 J Child Adolesc Psychopharmacol pmid:26091195
Villumsen IS et al. Pharmacological characterisation of murine α4β1δ GABAA receptors expressed in Xenopus oocytes. 2015 BMC Neurosci pmid:25887256
Ordoñez L et al. Spontaneous reporting of Stevens-Johnson syndrome and toxic epidermal necrolysis associated with antiepileptic drugs. 2015 Eur Rev Med Pharmacol Sci pmid:26221907
Wang H et al. Cocaine-Induced Endocannabinoid Mobilization in the Ventral Tegmental Area. 2015 Cell Rep pmid:26365195
Hieda K et al. Pharmacological effect of functional foods with a hypotensive action. 2015 Nippon Yakurigaku Zasshi pmid:26165340
Lee SH et al. Multiple Forms of Endocannabinoid and Endovanilloid Signaling Regulate the Tonic Control of GABA Release. 2015 J. Neurosci. pmid:26157003
Inkpen H Chronic progressive polyarthritis in a domestic shorthair cat. 2015 Can. Vet. J. pmid:26028686