4-aminobutyric acid

4-aminobutyric acid is a lipid of Fatty Acyls (FA) class. 4-aminobutyric acid is associated with abnormalities such as Epilepsy and Premenstrual syndrome. The involved functions are known as Binding (Molecular Function), neuron survival, Process, Uptake and physiological aspects. 4-aminobutyric acid often locates in Microglial, Neurofilament, Neuraxis, Brain region and Neurites. The associated genes with 4-aminobutyric acid are arginine methyl ester, SLC33A1 gene, NKS1 gene, P4HTM gene and ITSN2 gene. The related lipids are pregnenolone sulfate, pregnane-20-one, Pregnanes, Steroids and endogenous steroids.

Cross Reference

Introduction

To understand associated biological information of 4-aminobutyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with 4-aminobutyric acid?

4-aminobutyric acid is suspected in Premenstrual syndrome, Epilepsy and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 4-aminobutyric acid

MeSH term MeSH ID Detail
Fetal Alcohol Spectrum Disorders D063647 6 associated lipids
Genetic Diseases, Inborn D030342 4 associated lipids
Vitamin B 6 Deficiency D026681 10 associated lipids
Hyperammonemia D022124 5 associated lipids
Embryo Loss D020964 5 associated lipids
Paraparesis D020335 1 associated lipids
Neurotoxicity Syndromes D020258 34 associated lipids
Serotonin Syndrome D020230 1 associated lipids
Epilepsy, Reflex D020195 5 associated lipids
Gangliosidoses, GM2 D020143 1 associated lipids
Cocaine-Related Disorders D019970 3 associated lipids
Hemifacial Spasm D019569 1 associated lipids
Neck Pain D019547 2 associated lipids
Gingival Overgrowth D019214 7 associated lipids
Neuroaxonal Dystrophies D019150 3 associated lipids
Congenital Disorders of Glycosylation D018981 1 associated lipids
Encephalitis, Viral D018792 3 associated lipids
Tension-Type Headache D018781 1 associated lipids
Hypokinesia D018476 2 associated lipids
Neuroendocrine Tumors D018358 4 associated lipids
Per page 10 20 50 100 | Total 280

PubChem Associated disorders and diseases

What pathways are associated with 4-aminobutyric acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with 4-aminobutyric acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with 4-aminobutyric acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with 4-aminobutyric acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with 4-aminobutyric acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with 4-aminobutyric acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with 4-aminobutyric acid

Download all related citations
Per page 10 20 50 100 | Total 40318
Authors Title Published Journal PubMed Link
Bondarenko TI et al. [Concentration of free amino acids and homocarnosine dipeptide in the cerebrospinal fluid of children with hydrocephalus]. 1983 Zh Nevropatol Psikhiatr Im S S Korsakova pmid:6659780
Pozdniakov AV et al. [Proton magnetic-resonance spectroscopy in remitting and secondary-progressive multiple sclerosis]. 2001 Zh Nevrol Psikhiatr Im S S Korsakova pmid:11490432
MikhaÄ­lenko AA et al. [Patterns in the change of the evoked skin autonomic potential in nervous system diseases]. 1997 Zh Nevrol Psikhiatr Im S S Korsakova pmid:9214193
Skvortsova VI et al. [Levels of neurotransmitter amino acids in the cerebrospinal fluid of patients with acute ischemic stroke]. 1999 Zh Nevrol Psikhiatr Im S S Korsakova pmid:10081133
RaevskiÄ­ KS et al. [Features of neurotransmitter pool in cerebrospinal fluid of patients with epilepsy]. 2001 Zh Nevrol Psikhiatr Im S S Korsakova pmid:11517885
Tigranian RA et al. [The concentration of gamma-aminobutyric acid in brain tissue following cranio-cerebral trauma]. 1971 Zh Eksp Klin Med pmid:5161663
Mirzoian SA and Tatevosian AT [Content of neuroactive amino acids in the hypothalamus and liver of rats in experimental stomach ulcer and their changes under the effect of cholinolytic drugs]. 1975 Zh Eksp Klin Med pmid:7089
Estambale BB and Howells RE The efficacy of 22,23-dihydroavermectin B1 (Ivermectin) acting singly or in combination with a benzodiazepine on microfilariae of Onchocerca species and Brugia pahangi (an in vitro study). 1989 Zentralbl. Bakteriol. pmid:2775429
Pandey PK et al. Varying spectrum of amino acids in relation to growth in Helminthosporium oryzae Breda de Haan. 1979 Zentralbl Bakteriol Naturwiss pmid:573034
Ram RP et al. Fluctuation in amino-acid constituents of a developing culture of Sclerotium rolfsii Sacc. and its relation to growth. 1979 Zentralbl Bakteriol Naturwiss pmid:573035
Schubert R et al. [The glutamic acid decarboxylase disc test. An approach for the simplification and speeding up of E. coli detection]. 1988 Zentralbl Bakteriol Mikrobiol Hyg B pmid:3147554
Huckenbeck W and Daldrup T [Degradation of glutamic acid and proline in Clostridium sordellii under cadaveric bacteriological inspection]. 1984 Zentralbl Bakteriol Mikrobiol Hyg A pmid:6151765
Daldrup T and Huckenbeck W [Significance of the putrefactive bacterium Clostridium sordellii for the determination of age of the cadaver]. 1984 Z. Rechtsmed. pmid:6720104
Daldrup T [The kinetics of the postmortal bacterial metabolism of the glutamic acid in brain (author's transl)]. 1981 Z. Rechtsmed. pmid:7234135
Konecki J et al. Free amino acids in cytosol of rat brain after intraventricular administration of 5,6-dihydroxytryptamine and 6-hydroxydopamine. 1987 Z. Naturforsch., C, J. Biosci. pmid:2955598
Yamano K and Shirahama H The structure of a new dipeptide from the mushroom Clitocybe acromelalga. 1994 Mar-Apr Z. Naturforsch., C, J. Biosci. pmid:8018249
Leonard BE The effect of Org. GB 94, imipramine and chlorpromazine on the concentrations of some amino acids in 9 regions of the rat brain. 1975 Nov-Dec Z. Naturforsch., C, Biosci. pmid:130018
Campos-Ortega JA Autoradiographic localization of 3H-gamma-aminobutyric acid uptake in the lamina ganglionaris of Musca and Drosophila. 1974 Z Zellforsch Mikrosk Anat pmid:4847935
Scherer HU et al. [Polyarteritis nodosa - a "classical" case]. 2006 Z Rheumatol pmid:16450153
Mihály A Histochemistry and functional significance of putative neocortical transmitter substances: a review. 1982 Z Mikrosk Anat Forsch pmid:6190322
Carbajo S et al. Contribution to knowledge of GABAergic innervation of the intermediate lobe of the hypophysis. 1989 Z Mikrosk Anat Forsch pmid:2815926
Csoknya M et al. Histochemical characterization of myenteric plexus in domestic fowl small intestine. 1990 Z Mikrosk Anat Forsch pmid:2077764
Ritter J and Wenk H [Chemodifferentiation of the GABA-transaminase-SSA-dehydrogenase system of the olfactory blub, hippocampus and cerebellum during postnatal development of the albino rat]. 1974 Z Mikrosk Anat Forsch pmid:4156621
Golan-Goldhirsh A Effect of the add-back process on the free amino acid pool of potatoes. 1986 Z Lebensm Unters Forsch pmid:3953159
Weiller HG and Radler F [On the metabolism of amino acids by lactic acid bacteria isolated from wine (author's transl)]. 1976 Z Lebensm Unters Forsch pmid:973463
Averdunk R et al. [The role of cyclic AMP and Ca in the altered permeability of tumour cells grown with a deficiency of Mg]. 1975 Z Klin Chem Klin Biochem pmid:175590
Wendel A et al. [Assay and normal levels of L-glutamate-L-cysteine-gamma-ligase (E.C. 6.3.2.2) in human erythrocytes; biosynthesis of glutathione V]. 1975 Z Klin Chem Klin Biochem pmid:1154827
Vogler G [Efficient rapid isolation of E. coli faecalis from water by determining the decarboxylate gamma-aminobutyric acid by thin-layer chromatography]. 1980 Z Gesamte Hyg pmid:7006228
Ferenci P [Hepatic encephalopathy]. 1986 Z Gastroenterol Verh pmid:2422839
Petroianu G et al. [ETICS Study: Empirical therapy of idiopathic chronic singultus]. 1998 Z Gastroenterol pmid:9738303
Wienbeck M et al. [Neural regulation of the secretion of the small and large intestines]. 1987 Z Gastroenterol pmid:2438851
Gerster H [The importance of vitamin B 6 for development of the infant. Human medical and animal experiment studies]. 1996 Z Ernahrungswiss pmid:9082654
Langnickel R and Bluth R [Benzodiazepines--current aspects of the mechanism of action and clinically relevant questions]. 1983 Z Arztl Fortbild (Jena) pmid:6140796
Wiechert P [Significance of pyridoxine and gamma-aminobutyric acid in cerebral seizures]. 1971 Z Arztl Fortbild (Jena) pmid:4157324
Park DS et al. The effects of laminin on the characteristics and differentiation of neuronal cells from epidermal growth factor-responsive neuroepithelial cells. 1998 Yonsei Med. J. pmid:9587253
Han SH et al. Acquired pendular nystagmus with voluntary inhibition. 2001 Yonsei Med. J. pmid:11456403
Jung YC and Namkoong K Pharmacotherapy for alcohol dependence: anticraving medications for relapse prevention. 2006 Yonsei Med. J. pmid:16642544
McKelvey J et al. GABA transport in Saccharomyces cerevisiae. 1990 May-Jun Yeast pmid:2190434
Guo LJ et al. [Effects of gamma-aminobutyric acid on isolated dog cerebral arteries]. 1995 Yao Xue Xue Bao pmid:8571776
Zhou HY et al. [Effects of L-malate, an inhibitor of glutamate decarboxylase, on learning and memory in mice]. 1996 Yao Xue Xue Bao pmid:9863221
Wu Y et al. [Synthesis of N-(4-substituted amino-4-oxobutyryl)-N-substituted glycines]. 1992 Yao Xue Xue Bao pmid:1293947
Guo LJ and Philippu A [Effects of arterial blood pressure change on release of GABA in the posterior hypothalamus conscious of freely moving rats]. 1994 Yao Xue Xue Bao pmid:7992619
Zhang SS et al. [Cerebral glutamate/GABA system to regulate learning and memory]. 1997 Yao Xue Xue Bao pmid:11596319
Jin Y and Zhang SS [The inhibitory effect of succinic acid on the central nervous system (author's transl)]. 1980 Yao Xue Xue Bao pmid:7257803
Zhang SS and Jin Y [Central hypotensive effect of propranolol in relation to brain GABA receptors (author's transl)]. 1982 Yao Xue Xue Bao pmid:6283786
Shi LZ and Niu XY [Increase of 3H-GABA release from rat cultured cortex neurons after chronic exposure to MK801]. 1995 Yao Xue Xue Bao pmid:8701735
Zhang SS et al. [An analysis of the discrepancy between the effects of central and peripheral alpha-adrenoceptor stimulations (author's transl)]. 1979 Yao Xue Xue Bao pmid:231375
Yan H et al. A dynamic and quantitative study of pattern visual evoked potentials and gamma-aminobutyric acid neurones in the lateral geniculate nucleus and the visual cortex of monocular deprivation cats. 1996 Yan Ke Xue Bao pmid:9639837
Jones EA et al. The GABA hypothesis of the pathogenesis of hepatic encephalopathy: current status. 1984 May-Jun Yale J Biol Med pmid:6093394
Akaike N [Gamma-aminobutyric acid (GABA) activates three types of receptor-ionophore complex]. 1985 Yakugaku Zasshi pmid:2419541