4-aminobutyric acid

4-aminobutyric acid is a lipid of Fatty Acyls (FA) class. 4-aminobutyric acid is associated with abnormalities such as Epilepsy and Premenstrual syndrome. The involved functions are known as Binding (Molecular Function), neuron survival, Process, Uptake and physiological aspects. 4-aminobutyric acid often locates in Microglial, Neurofilament, Neuraxis, Brain region and Neurites. The associated genes with 4-aminobutyric acid are arginine methyl ester, SLC33A1 gene, NKS1 gene, P4HTM gene and ITSN2 gene. The related lipids are pregnenolone sulfate, pregnane-20-one, Pregnanes, Steroids and endogenous steroids.

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Introduction

To understand associated biological information of 4-aminobutyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with 4-aminobutyric acid?

4-aminobutyric acid is suspected in Premenstrual syndrome, Epilepsy and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 4-aminobutyric acid

MeSH term MeSH ID Detail
Cranial Nerve Diseases D003389 1 associated lipids
Epilepsy, Post-Traumatic D004834 1 associated lipids
Paraparesis D020335 1 associated lipids
Bulbar Palsy, Progressive D010244 1 associated lipids
Illusions D007088 1 associated lipids
Somatostatinoma D013005 1 associated lipids
Tension-Type Headache D018781 1 associated lipids
Aphakia D001035 1 associated lipids
Postpoliomyelitis Syndrome D016262 1 associated lipids
Stiff-Person Syndrome D016750 1 associated lipids
Gangliosidoses, GM2 D020143 1 associated lipids
Tetanus D013742 1 associated lipids
Pantothenate Kinase-Associated Neurodegeneration D006211 1 associated lipids
Encephalomyelitis, Venezuelan Equine D004685 1 associated lipids
Nervous System Malformations D009421 1 associated lipids
Epilepsy, Complex Partial D017029 1 associated lipids
Myofascial Pain Syndromes D009209 1 associated lipids
Meningitis, Aseptic D008582 1 associated lipids
Athetosis D001264 1 associated lipids
Syringomyelia D013595 1 associated lipids
Gangliosidosis, GM1 D016537 1 associated lipids
Serotonin Syndrome D020230 1 associated lipids
Torticollis D014103 1 associated lipids
Meige Syndrome D008538 1 associated lipids
Carcinoma, Acinar Cell D018267 1 associated lipids
Meningitis, Viral D008587 1 associated lipids
Arachnoid Cysts D016080 1 associated lipids
alpha-Mannosidosis D008363 1 associated lipids
Hiccup D006606 1 associated lipids
Chorea D002819 1 associated lipids
Congenital Disorders of Glycosylation D018981 1 associated lipids
Tongue, Fissured D014063 1 associated lipids
Neuroectodermal Tumors, Primitive D018242 1 associated lipids
Causalgia D002422 1 associated lipids
Polyradiculopathy D011128 1 associated lipids
Muscle Hypertonia D009122 1 associated lipids
Iatrogenic Disease D007049 1 associated lipids
Vision, Low D015354 1 associated lipids
Presbycusis D011304 1 associated lipids
Dandy-Walker Syndrome D003616 1 associated lipids
Hypernatremia D006955 1 associated lipids
Nelson Syndrome D009347 1 associated lipids
Gigantism D005877 1 associated lipids
Mitral Valve Prolapse D008945 1 associated lipids
Hemifacial Spasm D019569 1 associated lipids
High Pressure Neurological Syndrome D006610 1 associated lipids
Hypophosphatasia D007014 1 associated lipids
Phantom Limb D010591 1 associated lipids
Dystonia Musculorum Deformans D004422 1 associated lipids
Angelman Syndrome D017204 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with 4-aminobutyric acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with 4-aminobutyric acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with 4-aminobutyric acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with 4-aminobutyric acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with 4-aminobutyric acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with 4-aminobutyric acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with 4-aminobutyric acid

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Authors Title Published Journal PubMed Link
Ozbek Z et al. Neuroprotective Effect of Genistein in Peripheral Nerve Injury. 2017 Turk Neurosurg pmid:27759874
El-Habr EA et al. A driver role for GABA metabolism in controlling stem and proliferative cell state through GHB production in glioma. 2017 Acta Neuropathol. pmid:28032215
Moghbelinejad S et al. The effects of quercetin on the gene expression of the GABA receptor α5 subunit gene in a mouse model of kainic acid-induced seizure. 2017 J Physiol Sci pmid:27743178
Rowlands BD et al. Acetate metabolism does not reflect astrocytic activity, contributes directly to GABA synthesis, and is increased by silent information regulator 1 activation. 2017 J. Neurochem. pmid:27925207
Kaufmann D et al. sec-Butylpropylacetamide (SPD), a new amide derivative of valproic acid for the treatment of neuropathic and inflammatory pain. 2017 Pharmacol. Res. pmid:27890817
Roberts LD et al. Inorganic Nitrate Mimics Exercise-Stimulated Muscular Fiber-Type Switching and Myokine and γ-Aminobutyric Acid Release. 2017 Diabetes pmid:28028076
Li Z et al. Protective Effect of Resveratrol on the Brain in a Rat Model of Epilepsy. 2017 Neurosci Bull pmid:28161868
Beydemir Åž and Demir Y Antiepileptic drugs: Impacts on human serum paraoxonase-1. 2017 J. Biochem. Mol. Toxicol. pmid:28032682
Silva VO et al. Oral microbe-host interactions: influence of β-glucans on gene expression of inflammatory cytokines and metabolome profile. 2017 BMC Microbiol. pmid:28270109
He A et al. Unveiling the relative efficacy, safety and tolerability of prophylactic medications for migraine: pairwise and network-meta analysis. 2017 J Headache Pain pmid:28220376