4-aminobutyric acid is a lipid of Fatty Acyls (FA) class. 4-aminobutyric acid is associated with abnormalities such as Epilepsy and Premenstrual syndrome. The involved functions are known as Binding (Molecular Function), neuron survival, Process, Uptake and physiological aspects. 4-aminobutyric acid often locates in Microglial, Neurofilament, Neuraxis, Brain region and Neurites. The associated genes with 4-aminobutyric acid are arginine methyl ester, SLC33A1 gene, NKS1 gene, P4HTM gene and ITSN2 gene. The related lipids are pregnenolone sulfate, pregnane-20-one, Pregnanes, Steroids and endogenous steroids.
To understand associated biological information of 4-aminobutyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
4-aminobutyric acid is suspected in Premenstrual syndrome, Epilepsy and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with 4-aminobutyric acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Deeb S et al. | Simultaneous analysis of 22 antiepileptic drugs in postmortem blood, serum and plasma using LC-MS-MS with a focus on their role in forensic cases. | 2014 | J Anal Toxicol | pmid:25217536 |
Ari C et al. | Metabolic therapy with Deanna Protocol supplementation delays disease progression and extends survival in amyotrophic lateral sclerosis (ALS) mouse model. | 2014 | PLoS ONE | pmid:25061944 |
Cusmano DM and Mong JA | In utero exposure to valproic acid changes sleep in juvenile rats: a model for sleep disturbances in autism. | 2014 | Sleep | pmid:25142574 |
Bailey JN et al. | Hypothesis-independent pathway analysis implicates GABA and acetyl-CoA metabolism in primary open-angle glaucoma and normal-pressure glaucoma. | 2014 | Hum. Genet. | pmid:25037249 |
Mititelu Tartau L et al. | Synergic effects of pregabalin-acetaminophen combination in somatic and visceral nociceptive reactivity. | 2014 | Pharmacology | pmid:25059844 |
Pollock E et al. | Metalloproteinase inhibition prevents inhibitory synapse reorganization and seizure genesis. | 2014 | Neurobiol. Dis. | pmid:24946277 |
Blake CB and Smith BN | cAMP-dependent insulin modulation of synaptic inhibition in neurons of the dorsal motor nucleus of the vagus is altered in diabetic mice. | 2014 | Am. J. Physiol. Regul. Integr. Comp. Physiol. | pmid:24990858 |
Ikeda K et al. | Gas chromatography-electron ionization-mass spectrometry quantitation of valproic acid and gabapentin, using dried plasma spots, for therapeutic drug monitoring in in-home medical care. | 2014 | Biomed. Chromatogr. | pmid:24889681 |
Melis M et al. | Enhanced endocannabinoid-mediated modulation of rostromedial tegmental nucleus drive onto dopamine neurons in Sardinian alcohol-preferring rats. | 2014 | J. Neurosci. | pmid:25232109 |
Wilkins HM et al. | Oxaloacetate activates brain mitochondrial biogenesis, enhances the insulin pathway, reduces inflammation and stimulates neurogenesis. | 2014 | Hum. Mol. Genet. | pmid:25027327 |