4-aminobutyric acid
4-aminobutyric acid is a lipid of Fatty Acyls (FA) class. 4-aminobutyric acid is associated with abnormalities such as Epilepsy and Premenstrual syndrome. The involved functions are known as Binding (Molecular Function), neuron survival, Process, Uptake and physiological aspects. 4-aminobutyric acid often locates in Microglial, Neurofilament, Neuraxis, Brain region and Neurites. The associated genes with 4-aminobutyric acid are arginine methyl ester, SLC33A1 gene, NKS1 gene, P4HTM gene and ITSN2 gene. The related lipids are pregnenolone sulfate, pregnane-20-one, Pregnanes, Steroids and endogenous steroids.
Cross Reference
Introduction
To understand associated biological information of 4-aminobutyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with 4-aminobutyric acid?
4-aminobutyric acid is suspected in Premenstrual syndrome, Epilepsy and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with 4-aminobutyric acid
PubChem Associated disorders and diseases
What pathways are associated with 4-aminobutyric acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with 4-aminobutyric acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with 4-aminobutyric acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with 4-aminobutyric acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with 4-aminobutyric acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with 4-aminobutyric acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with 4-aminobutyric acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Nagamatsu S et al. | alpha-soluble N-ethylmaleimide-sensitive factor attachment protein is expressed in pancreatic beta cells and functions in insulin but not gamma-aminobutyric acid secretion. | 1999 | J. Biol. Chem. | pmid:10075705 |
| Jung CS et al. | The GABA(C) receptor is present in cone-horizontal cell axon terminals isolated from catfish retina. | 1999 | Neurosci. Lett. | pmid:10076898 |
| Jarry H et al. | Effects of age on GABA turnover rates in specific hypothalamic areas in female rats. | 1999 | Exp. Clin. Endocrinol. Diabetes | pmid:10077357 |
| Pesold C et al. | Cortical bitufted, horizontal, and Martinotti cells preferentially express and secrete reelin into perineuronal nets, nonsynaptically modulating gene expression. | 1999 | Proc. Natl. Acad. Sci. U.S.A. | pmid:10077664 |
| Christian M and Gillies G | Developing hypothalamic dopaminergic neurones as potential targets for environmental estrogens. | 1999 | J. Endocrinol. | pmid:10077742 |
| Zhang H et al. | Effects of GABA-mediated inhibition on direction-dependent frequency tuning in the frog inferior colliculus. | 1999 | J. Comp. Physiol. A | pmid:10077865 |
| Cestari IN et al. | GABA(A) receptor alpha4 subunit in DBA/2J and C57BL/6J mice. | 1998 | Brain Res. Bull. | pmid:10078620 |
| Sasaki K et al. | Effects of bilobalide on gamma-aminobutyric acid levels and glutamic acid decarboxylase in mouse brain. | 1999 | Eur. J. Pharmacol. | pmid:10078989 |
| Ong J et al. | Evaluation of 3-aminopropanesulphonamide analogues of GABA as antagonists at GABA(B) receptors in peripheral and central preparations. | 1999 | Eur. J. Pharmacol. | pmid:10078994 |
| Menke JJ and Heins JR | Treatment of postherpetic neuralgia. | 1999 Mar-Apr | J Am Pharm Assoc (Wash) | pmid:10079653 |
| Cotrufo R and Bonavita V | [Neurochemical and pharmacological principles in the therapy of epilepsies]. | 1976 Mar-Apr | Acta Neurol (Napoli) | pmid:1007978 |
| Subramanian P and Balamurugan E | Temporal oscillations of serum electrolytes in N-phthaloyl GABA-treated rats. | 1999 | Pharmacol. Biochem. Behav. | pmid:10080244 |
| Zahner B et al. | Once-daily versus twice-daily vigabatrin: is there a difference? The results of a double-blind pilot study. | 1999 | Epilepsia | pmid:10080511 |
| Bianchi L et al. | Simultaneous determination of basal and evoked output levels of aspartate, glutamate, taurine and 4-aminobutyric acid during microdialysis and from superfused brain slices. | 1999 | J. Chromatogr. B Biomed. Sci. Appl. | pmid:10080632 |
| Skvortsova VI et al. | [Levels of neurotransmitter amino acids in the cerebrospinal fluid of patients with acute ischemic stroke]. | 1999 | Zh Nevrol Psikhiatr Im S S Korsakova | pmid:10081133 |
| Meldrum B and Horton R | Blockade of epileptic responses in the photosensitive baboon, Papio papio, by two irreversible inhibitors of GABA-transaminase, gamma-acetylenic GABA (4-amino-hex-5-ynoic acid) and gamma-vinyl GABA (4-amino-hex-5-enoic acid). | 1978 | Psychopharmacology (Berl.) | pmid:100812 |
| Kamardin N et al. | Distinct responses of osphradial neurons to chemical stimuli and neurotransmitters in Lymnaea stagnalis L. | 1999 | Cell. Mol. Neurobiol. | pmid:10081607 |
| Honjo K et al. | GABA may function tonically via GABA(A) receptors to inhibit hypotension and bradycardia by L-DOPA microinjected into depressor sites of the nucleus tractus solitarii in anesthetized rats. | 1999 | Neurosci. Lett. | pmid:10081935 |
| Goshima Y et al. | The evidence for tonic GABAergic regulation of basal L-DOPA release via activation of inhibitory GABA(A) receptors in the nucleus tractus solitarii of anesthetized rats. | 1999 | Neurosci. Lett. | pmid:10081972 |
| Bloms-Funke P et al. | Extracellular single-unit recordings of piriform cortex neurons in rats: influence of different types of anesthesia and characterization of neurons by pharmacological manipulation of serotonin receptors. | 1999 | J. Neurosci. Res. | pmid:10082083 |
| Biswas B and Carlsson A | Effect of intraperitoneally administered GABA on the locomotor activity of mice. | 1978 | Psychopharmacology (Berl.) | pmid:100821 |
| Rezayat M et al. | Effects of CCK antagonists on GABA mechanism-induced antinociception in the formalin test. | 1999 | Eur Neuropsychopharmacol | pmid:10082222 |
| Mäkelä R et al. | Loreclezole and La3+ differentiate cerebellar granule cell GABA(A) receptor subtypes. | 1999 | Eur. J. Pharmacol. | pmid:10082271 |
| Koo B | Vigabatrin in the treatment of infantile spasms. | 1999 | Pediatr. Neurol. | pmid:10082337 |
| Messier C et al. | Contribution of cholinergic and gabaergic functions to memory processes in BALB/cANnCrlBR mice. | 1999 | Brain Res. | pmid:10082853 |
| Maitra R and Reynolds JN | Subunit dependent modulation of GABAA receptor function by neuroactive steroids. | 1999 | Brain Res. | pmid:10082863 |
| Kiyatkin EA and Rebec GV | Modulation of striatal neuronal activity by glutamate and GABA: iontophoresis in awake, unrestrained rats. | 1999 | Brain Res. | pmid:10082887 |
| Dvorak-Carbone H and Schuman EM | Long-term depression of temporoammonic-CA1 hippocampal synaptic transmission. | 1999 | J. Neurophysiol. | pmid:10085331 |
| Lin Q et al. | Inhibition of primate spinothalamic tract neurons by spinal glycine and GABA is modulated by guanosine 3',5'-cyclic monophosphate. | 1999 | J. Neurophysiol. | pmid:10085336 |
| Jensen K et al. | Role of presynaptic L-type Ca2+ channels in GABAergic synaptic transmission in cultured hippocampal neurons. | 1999 | J. Neurophysiol. | pmid:10085349 |
| Subramanian P et al. | Temporal oscillations of phosphatases in N-phthaloyl gamma-aminobutyric acid treated rats. | 1998 | Indian J. Exp. Biol. | pmid:10085783 |
| Seidl JJ and Slawson JG | Gabapentin for painful diabetic neuropathy. | 1999 | J Fam Pract | pmid:10086757 |
| Mozrzymas JW et al. | Chlorpromazine inhibits miniature GABAergic currents by reducing the binding and by increasing the unbinding rate of GABAA receptors. | 1999 | J. Neurosci. | pmid:10087062 |
| Verheugen JA et al. | Noninvasive measurements of the membrane potential and GABAergic action in hippocampal interneurons. | 1999 | J. Neurosci. | pmid:10087068 |
| Polgár E et al. | GABAergic neurons that contain neuropeptide Y selectively target cells with the neurokinin 1 receptor in laminae III and IV of the rat spinal cord. | 1999 | J. Neurosci. | pmid:10087077 |
| Alkondon M et al. | Choline and selective antagonists identify two subtypes of nicotinic acetylcholine receptors that modulate GABA release from CA1 interneurons in rat hippocampal slices. | 1999 | J. Neurosci. | pmid:10087082 |
| Brussaard AB et al. | Changes in properties and neurosteroid regulation of GABAergic synapses in the supraoptic nucleus during the mammalian female reproductive cycle. | 1999 | J. Physiol. (Lond.) | pmid:10087349 |
| Ferraro L et al. | The vigilance promoting drug modafinil increases extracellular glutamate levels in the medial preoptic area and the posterior hypothalamus of the conscious rat: prevention by local GABAA receptor blockade. | 1999 | Neuropsychopharmacology | pmid:10088135 |
| Rogers HJ and Lietman PS | Inhibition by trimethoprim of some effects of epidermal growth factor on human fibroblasts in tissue culture. | 1976 | Biochem. Pharmacol. | pmid:1008900 |
| Möck M et al. | GABAergic inhibition in the rat pontine nuclei is exclusively extrinsic: evidence from an in situ hybridization study for GAD67 mRNA. | 1999 | Exp Brain Res | pmid:10090666 |
| Jóźwiak L et al. | Behavioral studies of the effects of moderate oligemic hypoxia caused by bilateral clamping of carotid arteries in mice. Impairment of spatial working memory. | 1998 Jul-Oct | Pol J Pharmacol | pmid:10091712 |
| pmid:10091848 | ||||
| Rosina A et al. | GAT-1 developmental expression in the rat cerebellar cortex: basket and pinceau formation. | 1999 | Neuroreport | pmid:10094127 |
| Mata MM et al. | On GABA function and physiology in the pineal gland. | 1976 | Brain Res. | pmid:1009426 |
| Coyle JT and Yamamura HI | Neurochemical aspects of the ontogenesis of cholinergic neurons in the rat brain. | 1976 | Brain Res. | pmid:1009427 |
| Deschenes M et al. | A model for an estimate in vivo of the ionic basis of presynaptic inhibition: an intracellular analysis of the GABA-induced depolarization in rat dorsal root ganglia. | 1976 | Brain Res. | pmid:1009434 |
| Deschenes M and Feltz P | GABA-induced rise of extracellular potassium in rat dorsal root ganglia: an electrophysiological study in vivo. | 1976 | Brain Res. | pmid:1009435 |
| Stringer JL and Lorenzo N | The reduction in paired-pulse inhibition in the rat hippocampus by gabapentin is independent of GABA(B) receptor receptor activation. | 1999 | Epilepsy Res. | pmid:10094428 |
| Yoon YH et al. | High vulnerability of GABA-immunoreactive neurons to kainate in rat retinal cultures: correlation with the kainate-stimulated cobalt uptake. | 1999 | Brain Res. | pmid:10095009 |
| Hylland P and Nilsson GE | Extracellular levels of amino acid neurotransmitters during anoxia and forced energy deficiency in crucian carp brain. | 1999 | Brain Res. | pmid:10095011 |