4-aminobutyric acid

4-aminobutyric acid is a lipid of Fatty Acyls (FA) class. 4-aminobutyric acid is associated with abnormalities such as Epilepsy and Premenstrual syndrome. The involved functions are known as Binding (Molecular Function), neuron survival, Process, Uptake and physiological aspects. 4-aminobutyric acid often locates in Microglial, Neurofilament, Neuraxis, Brain region and Neurites. The associated genes with 4-aminobutyric acid are arginine methyl ester, SLC33A1 gene, NKS1 gene, P4HTM gene and ITSN2 gene. The related lipids are pregnenolone sulfate, pregnane-20-one, Pregnanes, Steroids and endogenous steroids.

Cross Reference

Introduction

To understand associated biological information of 4-aminobutyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with 4-aminobutyric acid?

4-aminobutyric acid is suspected in Premenstrual syndrome, Epilepsy and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 4-aminobutyric acid

MeSH term MeSH ID Detail
Acidosis, Lactic D000140 8 associated lipids
Adenocarcinoma D000230 166 associated lipids
Adenoma D000236 40 associated lipids
Adrenal Cortex Diseases D000303 1 associated lipids
Adrenoleukodystrophy D000326 29 associated lipids
Alcohol Amnestic Disorder D000425 2 associated lipids
Alcoholic Intoxication D000435 15 associated lipids
Alcoholism D000437 27 associated lipids
Alzheimer Disease D000544 76 associated lipids
Renal Aminoacidurias D000608 2 associated lipids
Amnesia D000647 12 associated lipids
Amnesia, Retrograde D000648 2 associated lipids
Amyotrophic Lateral Sclerosis D000690 11 associated lipids
Aphakia D001035 1 associated lipids
Arachnoiditis D001100 1 associated lipids
Arrhythmias, Cardiac D001145 42 associated lipids
Arthritis D001168 41 associated lipids
Arthritis, Experimental D001169 24 associated lipids
Ascorbic Acid Deficiency D001206 9 associated lipids
Asphyxia D001237 5 associated lipids
Asthenia D001247 5 associated lipids
Ataxia D001259 20 associated lipids
Athetosis D001264 1 associated lipids
Autoimmune Diseases D001327 27 associated lipids
Basal Ganglia Diseases D001480 8 associated lipids
Urinary Bladder, Neurogenic D001750 3 associated lipids
Body Weight D001835 333 associated lipids
Bradycardia D001919 13 associated lipids
Brain Damage, Chronic D001925 6 associated lipids
Brain Diseases D001927 27 associated lipids
Brain Diseases, Metabolic D001928 9 associated lipids
Brain Edema D001929 20 associated lipids
Catalepsy D002375 30 associated lipids
Catatonia D002389 2 associated lipids
Causalgia D002422 1 associated lipids
Cell Transformation, Neoplastic D002471 126 associated lipids
Central Nervous System Diseases D002493 10 associated lipids
Cerebellar Ataxia D002524 3 associated lipids
Cerebellar Neoplasms D002528 9 associated lipids
Hypoxia, Brain D002534 5 associated lipids
Cerebral Hemorrhage D002543 13 associated lipids
Brain Ischemia D002545 89 associated lipids
Ischemic Attack, Transient D002546 42 associated lipids
Cerebrovascular Disorders D002561 25 associated lipids
Cestode Infections D002590 3 associated lipids
Chorea D002819 1 associated lipids
Choristoma D002828 1 associated lipids
Cleft Palate D002972 9 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Common Bile Duct Diseases D003137 3 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with 4-aminobutyric acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with 4-aminobutyric acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with 4-aminobutyric acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with 4-aminobutyric acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with 4-aminobutyric acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with 4-aminobutyric acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with 4-aminobutyric acid

Download all related citations
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Authors Title Published Journal PubMed Link
Deeb S et al. Simultaneous analysis of 22 antiepileptic drugs in postmortem blood, serum and plasma using LC-MS-MS with a focus on their role in forensic cases. 2014 J Anal Toxicol pmid:25217536
Ari C et al. Metabolic therapy with Deanna Protocol supplementation delays disease progression and extends survival in amyotrophic lateral sclerosis (ALS) mouse model. 2014 PLoS ONE pmid:25061944
Cusmano DM and Mong JA In utero exposure to valproic acid changes sleep in juvenile rats: a model for sleep disturbances in autism. 2014 Sleep pmid:25142574
Bailey JN et al. Hypothesis-independent pathway analysis implicates GABA and acetyl-CoA metabolism in primary open-angle glaucoma and normal-pressure glaucoma. 2014 Hum. Genet. pmid:25037249
Mititelu Tartau L et al. Synergic effects of pregabalin-acetaminophen combination in somatic and visceral nociceptive reactivity. 2014 Pharmacology pmid:25059844
Pollock E et al. Metalloproteinase inhibition prevents inhibitory synapse reorganization and seizure genesis. 2014 Neurobiol. Dis. pmid:24946277
Blake CB and Smith BN cAMP-dependent insulin modulation of synaptic inhibition in neurons of the dorsal motor nucleus of the vagus is altered in diabetic mice. 2014 Am. J. Physiol. Regul. Integr. Comp. Physiol. pmid:24990858
Ikeda K et al. Gas chromatography-electron ionization-mass spectrometry quantitation of valproic acid and gabapentin, using dried plasma spots, for therapeutic drug monitoring in in-home medical care. 2014 Biomed. Chromatogr. pmid:24889681
Melis M et al. Enhanced endocannabinoid-mediated modulation of rostromedial tegmental nucleus drive onto dopamine neurons in Sardinian alcohol-preferring rats. 2014 J. Neurosci. pmid:25232109
Wilkins HM et al. Oxaloacetate activates brain mitochondrial biogenesis, enhances the insulin pathway, reduces inflammation and stimulates neurogenesis. 2014 Hum. Mol. Genet. pmid:25027327