4-aminobutyric acid
4-aminobutyric acid is a lipid of Fatty Acyls (FA) class. 4-aminobutyric acid is associated with abnormalities such as Epilepsy and Premenstrual syndrome. The involved functions are known as Binding (Molecular Function), neuron survival, Process, Uptake and physiological aspects. 4-aminobutyric acid often locates in Microglial, Neurofilament, Neuraxis, Brain region and Neurites. The associated genes with 4-aminobutyric acid are arginine methyl ester, SLC33A1 gene, NKS1 gene, P4HTM gene and ITSN2 gene. The related lipids are pregnenolone sulfate, pregnane-20-one, Pregnanes, Steroids and endogenous steroids.
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Introduction
To understand associated biological information of 4-aminobutyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with 4-aminobutyric acid?
4-aminobutyric acid is suspected in Premenstrual syndrome, Epilepsy and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with 4-aminobutyric acid
PubChem Associated disorders and diseases
What pathways are associated with 4-aminobutyric acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with 4-aminobutyric acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with 4-aminobutyric acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with 4-aminobutyric acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with 4-aminobutyric acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with 4-aminobutyric acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with 4-aminobutyric acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Platt B and Withington DJ | GABA-induced long-term potentiation in the guinea-pig superior colliculus. | 1998 | Neuropharmacology | pmid:9833641 |
| Sooksawate T and Simmonds MA | Increased membrane cholesterol reduces the potentiation of GABA(A) currents by neurosteroids in dissociated hippocampal neurones. | 1998 | Neuropharmacology | pmid:9833640 |
| Anseloni VZ and Brandão ML | Ethopharmacological analysis of behaviour of rats using variations of the elevated plus-maze. | 1997 | Behav Pharmacol | pmid:9832967 |
| Haller J et al. | Aggressive experience affects the sensitivity of neurons towards pharmacological treatment in the hypothalamic attack area. | 1998 | Behav Pharmacol | pmid:9832932 |
| Blázquez M et al. | Gamma-aminobutyric acid up-regulates the expression of a novel secretogranin-II messenger ribonucleic acid in the goldfish pituitary. | 1998 | Endocrinology | pmid:9832423 |
| Smith AJ et al. | Benzodiazepine modulation of recombinant alpha1beta3gamma2 GABA(A) receptor function efficacy determination using the Cytosensor microphysiometer. | 1998 | Eur. J. Pharmacol. | pmid:9832398 |
| Hanania T and Johnson KM | Regulation of neurotransmitter release by endogenous nitric oxide in striatal slices. | 1998 | Eur. J. Pharmacol. | pmid:9832380 |
| Stefanova N | Gamma-aminobutyric acid-immunoreactive neurons in the amygdala of the rat - sex differences and effect of early postnatal castration. | 1998 | Neurosci. Lett. | pmid:9832201 |
| Yang K et al. | Capsaicin facilitates excitatory but not inhibitory synaptic transmission in substantia gelatinosa of the rat spinal cord. | 1998 | Neurosci. Lett. | pmid:9832191 |
| New KC and Rabkin SD | GABA synthesis in astrocytes after infection with defective herpes simplex virus vectors expressing glutamic acid decarboxylase 65 or 67. | 1998 | J. Neurochem. | pmid:9832128 |
| Wu SP et al. | Frequency-dependent inhibition of neuronal activity by topiramate in rat hippocampal slices. | 1998 | Br. J. Pharmacol. | pmid:9831921 |
| Tömböl T | Golgi and electron-microscopic golgi-GABA immunostaining study of the avian optic tectum. | 1998 | Acta Anat (Basel) | pmid:9831770 |
| Hanitzsch R et al. | Impaired function of bipolar cells in the Royal College of Surgeons rat. | 1998 | Acta Anat (Basel) | pmid:9831758 |
| Haas KF and Macdonald RL | GABAA receptor subunit gamma2 and delta subtypes confer unique kinetic properties on recombinant GABAA receptor currents in mouse fibroblasts. | 1999 | J. Physiol. (Lond.) | pmid:9831714 |
| Ikeda T et al. | Dieldrin and picrotoxinin modulation of GABA(A) receptor single channels. | 1998 | Neuroreport | pmid:9831449 |
| Shevelev IA et al. | Contribution of GABAergic inhibition to sensitivity to cross-like figures in striate cortex. | 1998 | Neuroreport | pmid:9831443 |
| Gonzalez-Sicilia L et al. | Stevens-Johnson syndrome associated with gabapentin. | 1998 | Am. J. Med. | pmid:9831433 |
| Ogawa H et al. | GABAergic inhibition and modifications of taste responses in the cortical taste area in rats. | 1998 | Neurosci. Res. | pmid:9831255 |
| Kiser PJ et al. | Expression of two forms of glutamic acid decarboxylase (GAD67 and GAD65) during postnatal development of rat somatosensory barrel cortex. | 1998 | J. Comp. Neurol. | pmid:9831046 |
| Dunne EL et al. | Inhibition of GABAA receptor function by tyrosine kinase inhibitors and their inactive analogues. | 1998 | Mol. Cell. Neurosci. | pmid:9828093 |