4-aminobutyric acid

4-aminobutyric acid is a lipid of Fatty Acyls (FA) class. 4-aminobutyric acid is associated with abnormalities such as Epilepsy and Premenstrual syndrome. The involved functions are known as Binding (Molecular Function), neuron survival, Process, Uptake and physiological aspects. 4-aminobutyric acid often locates in Microglial, Neurofilament, Neuraxis, Brain region and Neurites. The associated genes with 4-aminobutyric acid are arginine methyl ester, SLC33A1 gene, NKS1 gene, P4HTM gene and ITSN2 gene. The related lipids are pregnenolone sulfate, pregnane-20-one, Pregnanes, Steroids and endogenous steroids.

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Introduction

To understand associated biological information of 4-aminobutyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with 4-aminobutyric acid?

4-aminobutyric acid is suspected in Premenstrual syndrome, Epilepsy and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 4-aminobutyric acid

MeSH term MeSH ID Detail
Fetal Alcohol Spectrum Disorders D063647 6 associated lipids
Genetic Diseases, Inborn D030342 4 associated lipids
Vitamin B 6 Deficiency D026681 10 associated lipids
Hyperammonemia D022124 5 associated lipids
Embryo Loss D020964 5 associated lipids
Paraparesis D020335 1 associated lipids
Neurotoxicity Syndromes D020258 34 associated lipids
Serotonin Syndrome D020230 1 associated lipids
Epilepsy, Reflex D020195 5 associated lipids
Gangliosidoses, GM2 D020143 1 associated lipids
Cocaine-Related Disorders D019970 3 associated lipids
Hemifacial Spasm D019569 1 associated lipids
Neck Pain D019547 2 associated lipids
Gingival Overgrowth D019214 7 associated lipids
Neuroaxonal Dystrophies D019150 3 associated lipids
Congenital Disorders of Glycosylation D018981 1 associated lipids
Encephalitis, Viral D018792 3 associated lipids
Tension-Type Headache D018781 1 associated lipids
Hypokinesia D018476 2 associated lipids
Neuroendocrine Tumors D018358 4 associated lipids
Carcinoma, Acinar Cell D018267 1 associated lipids
Neuroectodermal Tumors, Primitive D018242 1 associated lipids
Carcinoma, Embryonal D018236 8 associated lipids
Angelman Syndrome D017204 1 associated lipids
Porphyria, Acute Intermittent D017118 3 associated lipids
Low Back Pain D017116 2 associated lipids
Akathisia, Drug-Induced D017109 2 associated lipids
Epilepsy, Complex Partial D017029 1 associated lipids
Stiff-Person Syndrome D016750 1 associated lipids
Primary Ovarian Insufficiency D016649 2 associated lipids
Gangliosidosis, GM1 D016537 1 associated lipids
Postpoliomyelitis Syndrome D016262 1 associated lipids
Arachnoid Cysts D016080 1 associated lipids
Ocular Motility Disorders D015835 2 associated lipids
Gyrate Atrophy D015799 2 associated lipids
Granuloma, Foreign-Body D015745 5 associated lipids
Weight Loss D015431 56 associated lipids
Weight Gain D015430 101 associated lipids
Reperfusion Injury D015427 65 associated lipids
Retinal Artery Occlusion D015356 2 associated lipids
Vision, Low D015354 1 associated lipids
Wounds and Injuries D014947 20 associated lipids
Wernicke Encephalopathy D014899 2 associated lipids
Vertigo D014717 4 associated lipids
Ventricular Fibrillation D014693 16 associated lipids
Varicose Veins D014648 7 associated lipids
Uremia D014511 33 associated lipids
Tuberous Sclerosis D014402 2 associated lipids
Tuberculosis, Meningeal D014390 3 associated lipids
Tremor D014202 15 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with 4-aminobutyric acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with 4-aminobutyric acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with 4-aminobutyric acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with 4-aminobutyric acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with 4-aminobutyric acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with 4-aminobutyric acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with 4-aminobutyric acid

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Authors Title Published Journal PubMed Link
Trotti LM et al. Clarithromycin in γ-aminobutyric acid-Related hypersomnolence: A randomized, crossover trial. 2015 Ann. Neurol. pmid:26094838
Zhao W et al. A study on quality components and sleep-promoting effects of GABA black tea. 2015 Food Funct pmid:26290415
Bönnighausen J et al. Disruption of the GABA shunt affects mitochondrial respiration and virulence in the cereal pathogen Fusarium graminearum. 2015 Mol. Microbiol. pmid:26305050
Mirabella R et al. WRKY40 and WRKY6 act downstream of the green leaf volatile E-2-hexenal in Arabidopsis. 2015 Plant J. pmid:26243404
Sikoglu EM et al. Vitamin D3 Supplemental Treatment for Mania in Youth with Bipolar Spectrum Disorders. 2015 J Child Adolesc Psychopharmacol pmid:26091195
Villumsen IS et al. Pharmacological characterisation of murine α4β1δ GABAA receptors expressed in Xenopus oocytes. 2015 BMC Neurosci pmid:25887256
Ordoñez L et al. Spontaneous reporting of Stevens-Johnson syndrome and toxic epidermal necrolysis associated with antiepileptic drugs. 2015 Eur Rev Med Pharmacol Sci pmid:26221907
Hieda K et al. Pharmacological effect of functional foods with a hypotensive action. 2015 Nippon Yakurigaku Zasshi pmid:26165340
Lee SH et al. Multiple Forms of Endocannabinoid and Endovanilloid Signaling Regulate the Tonic Control of GABA Release. 2015 J. Neurosci. pmid:26157003
Inkpen H Chronic progressive polyarthritis in a domestic shorthair cat. 2015 Can. Vet. J. pmid:26028686