4-aminobutyric acid is a lipid of Fatty Acyls (FA) class. 4-aminobutyric acid is associated with abnormalities such as Epilepsy and Premenstrual syndrome. The involved functions are known as Binding (Molecular Function), neuron survival, Process, Uptake and physiological aspects. 4-aminobutyric acid often locates in Microglial, Neurofilament, Neuraxis, Brain region and Neurites. The associated genes with 4-aminobutyric acid are arginine methyl ester, SLC33A1 gene, NKS1 gene, P4HTM gene and ITSN2 gene. The related lipids are pregnenolone sulfate, pregnane-20-one, Pregnanes, Steroids and endogenous steroids.
To understand associated biological information of 4-aminobutyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
4-aminobutyric acid is suspected in Premenstrual syndrome, Epilepsy and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with 4-aminobutyric acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
Lipid concept | Cross reference | Weighted score | Related literatures |
---|
Gene | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Pérez-Redondo R et al. | ArgR of Streptomyces coelicolor is a versatile regulator. | 2012 | PLoS ONE | pmid:22403700 |
Voss U et al. | Glucagon-like peptides 1 and 2 and vasoactive intestinal peptide are neuroprotective on cultured and mast cell co-cultured rat myenteric neurons. | 2012 | BMC Gastroenterol | pmid:22463807 |
Capozzi V et al. | Biotechnology and pasta-making: lactic Acid bacteria as a new driver of innovation. | 2012 | Front Microbiol | pmid:22457660 |
Kaczmarek-Hájek K et al. | Molecular and functional properties of P2X receptors--recent progress and persisting challenges. | 2012 | Purinergic Signal. | pmid:22547202 |
Fournier S et al. | Corticosterone promotes emergence of fictive air breathing in Xenopus laevis Daudin tadpole brainstems. | 2012 | J. Exp. Biol. | pmid:22399659 |
Zhang M et al. | Effect of dietary γ-aminobutyric acid on laying performance, egg quality, immune activity and endocrine hormone in heat-stressed Roman hens. | 2012 | Anim. Sci. J. | pmid:22339695 |
Gold M et al. | Critical appraisal of the role of davunetide in the treatment of progressive supranuclear palsy. | 2012 | Neuropsychiatr Dis Treat | pmid:22347799 |
Crépin A et al. | Quorum sensing signaling molecules produced by reference and emerging soft-rot bacteria (Dickeya and Pectobacterium spp.). | 2012 | PLoS ONE | pmid:22539957 |
Wyrembek P et al. | Falcarindiol allosterically modulates GABAergic currents in cultured rat hippocampal neurons. | 2012 | J. Nat. Prod. | pmid:22432736 |
MartÃnez-Antonio A et al. | Regulatory design governing progression of population growth phases in bacteria. | 2012 | PLoS ONE | pmid:22363461 |
de Soysa TY et al. | Macondo crude oil from the Deepwater Horizon oil spill disrupts specific developmental processes during zebrafish embryogenesis. | 2012 | BMC Biol. | pmid:22559716 |
Buddhala C et al. | Calpain cleavage of brain glutamic acid decarboxylase 65 is pathological and impairs GABA neurotransmission. | 2012 | PLoS ONE | pmid:22427928 |
Amoateng P et al. | Anticonvulsant and related neuropharmacological effects of the whole plant extract of Synedrella nodiflora (L.) Gaertn (Asteraceae). | 2012 | J Pharm Bioallied Sci | pmid:22557925 |
Cao S et al. | A mitochondria-dependent pathway mediates the apoptosis of GSE-induced yeast. | 2012 | PLoS ONE | pmid:22403727 |
Schumacher M et al. | Progesterone synthesis in the nervous system: implications for myelination and myelin repair. | 2012 | Front Neurosci | pmid:22347156 |
Guttuso T | Nighttime awakenings responding to gabapentin therapy in late premenopausal women: a case series. | 2012 | J Clin Sleep Med | pmid:22505864 |
Popic J et al. | Propofol-induced changes in neurotrophic signaling in the developing nervous system in vivo. | 2012 | PLoS ONE | pmid:22496799 |
Martin FP et al. | Metabolomic applications to decipher gut microbial metabolic influence in health and disease. | 2012 | Front Physiol | pmid:22557976 |
Mathew J et al. | Decreased GABA receptor in the cerebral cortex of epileptic rats: effect of Bacopa monnieri and Bacoside-A. | 2012 | J. Biomed. Sci. | pmid:22364254 |
Malek AA et al. | Absence of membrane phosphatidylcholine does not affect virulence and stress tolerance phenotypes in the opportunistic pathogen Pseudomonas aeruginosa. | 2012 | PLoS ONE | pmid:22363496 |
Bregestovski P and Bernard C | Excitatory GABA: How a Correct Observation May Turn Out to be an Experimental Artifact. | 2012 | Front Pharmacol | pmid:22529813 |
Khakhalin AS and Aizenman CD | GABAergic transmission and chloride equilibrium potential are not modulated by pyruvate in the developing optic tectum of Xenopus laevis tadpoles. | 2012 | PLoS ONE | pmid:22496804 |
Shetty PK et al. | Cellular Links between Neuronal Activity and Energy Homeostasis. | 2012 | Front Pharmacol | pmid:22470340 |
Mulligan MK et al. | Complex control of GABA(A) receptor subunit mRNA expression: variation, covariation, and genetic regulation. | 2012 | PLoS ONE | pmid:22506031 |
Hayashi Y et al. | Neuropathological similarities and differences between schizophrenia and bipolar disorder: a flow cytometric postmortem brain study. | 2012 | PLoS ONE | pmid:22438888 |
Streeter CC et al. | Effects of yoga on the autonomic nervous system, gamma-aminobutyric-acid, and allostasis in epilepsy, depression, and post-traumatic stress disorder. | 2012 | Med. Hypotheses | pmid:22365651 |
Chamma I et al. | Role of the neuronal K-Cl co-transporter KCC2 in inhibitory and excitatory neurotransmission. | 2012 | Front Cell Neurosci | pmid:22363264 |
Roth FC and Draguhn A | GABA metabolism and transport: effects on synaptic efficacy. | 2012 | Neural Plast. | pmid:22530158 |
Shin HW and Chung SJ | Drug-induced parkinsonism. | 2012 | J Clin Neurol | pmid:22523509 |
Diamantopoulou A et al. | Denial of reward in the neonate shapes sociability and serotonergic activity in the adult rat. | 2012 | PLoS ONE | pmid:22479443 |
Bouchez G et al. | Quantification of extracellular levels of corticosterone in the basolateral amygdaloid complex of freely-moving rats: a dialysis study of circadian variation and stress-induced modulation. | 2012 | Brain Res. | pmid:22464880 |
Byun SH and Jeon YH | Treatment of idiopathic persistent hiccups with positive pressure ventilation -a case report-. | 2012 | Korean J Pain | pmid:22514778 |
Wadman RI et al. | Drug treatment for spinal muscular atrophy types II and III. | 2012 | Cochrane Database Syst Rev | pmid:22513940 |
Hossaini M et al. | Distribution of glycine/GABA neurons in the ventromedial medulla with descending spinal projections and evidence for an ascending glycine/GABA projection. | 2012 | PLoS ONE | pmid:22558137 |
Xie W et al. | Pyrosequencing the Bemisia tabaci transcriptome reveals a highly diverse bacterial community and a robust system for insecticide resistance. | 2012 | PLoS ONE | pmid:22558125 |
Segklia A et al. | Bmp7 regulates the survival, proliferation, and neurogenic properties of neural progenitor cells during corticogenesis in the mouse. | 2012 | PLoS ONE | pmid:22461901 |
Tachikawa M et al. | γ-Aminobutyric acid transporter 2 mediates the hepatic uptake of guanidinoacetate, the creatine biosynthetic precursor, in rats. | 2012 | PLoS ONE | pmid:22384273 |
Suchecki D et al. | REM Sleep Rebound as an Adaptive Response to Stressful Situations. | 2012 | Front Neurol | pmid:22485105 |
Levi CE et al. | GABA induction of the Saccharomyces cerevisiae UGA4 gene depends on the quality of the carbon source: role of the key transcription factors acting in this process. | 2012 | Biochem. Biophys. Res. Commun. | pmid:22525679 |
Hellier JL et al. | α7-Nicotinic acetylcholine receptor: role in early odor learning preference in mice. | 2012 | PLoS ONE | pmid:22514723 |
Yoshimura Y et al. | Different localization patterns of anthocyanin species in the pericarp of black rice revealed by imaging mass spectrometry. | 2012 | PLoS ONE | pmid:22363605 |
Asiedu MN et al. | Modulation of spinal GABAergic analgesia by inhibition of chloride extrusion capacity in mice. | 2012 | J Pain | pmid:22537560 |
Szczot M et al. | Modulation of GABAergic synaptic currents and current responses by α-thujone and dihydroumbellulone. | 2012 | J. Nat. Prod. | pmid:22364543 |
Demirbilek H et al. | Hypophosphatasia presenting with pyridoxine-responsive seizures, hypercalcemia, and pseudotumor cerebri: case report. | 2012 | J Clin Res Pediatr Endocrinol | pmid:22394703 |
Addae C et al. | All-trans-retinoid acid induces the differentiation of encapsulated mouse embryonic stem cells into GABAergic neurons. | 2012 | Differentiation | pmid:22466603 |
Zhang Q et al. | Early exercise affects mitochondrial transcription factors expression after cerebral ischemia in rats. | 2012 | Int J Mol Sci | pmid:22408416 |
Frankle WG et al. | [11C]flumazenil binding is increased in a dose-dependent manner with tiagabine-induced elevations in GABA levels. | 2012 | PLoS ONE | pmid:22384252 |
Balagurunathan B et al. | Reconstruction and analysis of a genome-scale metabolic model for Scheffersomyces stipitis. | 2012 | Microb. Cell Fact. | pmid:22356827 |
Braakman R and Smith E | The emergence and early evolution of biological carbon-fixation. | 2012 | PLoS Comput. Biol. | pmid:22536150 |
Kim JW et al. | Alcohol and cognition in the elderly: a review. | 2012 | Psychiatry Investig | pmid:22396679 |