4-aminobutyric acid

4-aminobutyric acid is a lipid of Fatty Acyls (FA) class. 4-aminobutyric acid is associated with abnormalities such as Epilepsy and Premenstrual syndrome. The involved functions are known as Binding (Molecular Function), neuron survival, Process, Uptake and physiological aspects. 4-aminobutyric acid often locates in Microglial, Neurofilament, Neuraxis, Brain region and Neurites. The associated genes with 4-aminobutyric acid are arginine methyl ester, SLC33A1 gene, NKS1 gene, P4HTM gene and ITSN2 gene. The related lipids are pregnenolone sulfate, pregnane-20-one, Pregnanes, Steroids and endogenous steroids.

Cross Reference

Introduction

To understand associated biological information of 4-aminobutyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with 4-aminobutyric acid?

4-aminobutyric acid is suspected in Premenstrual syndrome, Epilepsy and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 4-aminobutyric acid

MeSH term MeSH ID Detail
Retinoblastoma D012175 12 associated lipids
Retrograde Degeneration D012183 4 associated lipids
Reye Syndrome D012202 14 associated lipids
Sarcoma, Experimental D012513 13 associated lipids
Sarcoma, Yoshida D012517 5 associated lipids
Sclerosis D012598 5 associated lipids
Scrapie D012608 7 associated lipids
Seizures D012640 87 associated lipids
Self Mutilation D012652 2 associated lipids
Skin Diseases, Vesiculobullous D012872 5 associated lipids
Sleep Deprivation D012892 5 associated lipids
Sleep Wake Disorders D012893 7 associated lipids
Somatostatinoma D013005 1 associated lipids
Spasms, Infantile D013036 3 associated lipids
Spinal Cord Diseases D013118 4 associated lipids
Spinal Cord Injuries D013119 34 associated lipids
Starvation D013217 47 associated lipids
Stomach Neoplasms D013274 24 associated lipids
Stomach Ulcer D013276 75 associated lipids
Strabismus D013285 1 associated lipids
Per page 10 20 50 100 | Total 280

PubChem Associated disorders and diseases

What pathways are associated with 4-aminobutyric acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with 4-aminobutyric acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with 4-aminobutyric acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with 4-aminobutyric acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with 4-aminobutyric acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with 4-aminobutyric acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with 4-aminobutyric acid

Download all related citations
Per page 10 20 50 100 | Total 40318
Authors Title Published Journal PubMed Link
pmid:9757034
pmid:9758155
pmid:9758225
pmid:9758228
Villeneuve N et al. [Treatment of infantile spasms with vigabatrin as first-line therapy and in monotherapy: apropos of 70 infants]. 1998 Arch Pediatr pmid:9759271
pmid:9759916
pmid:9759971
pmid:9759975
pmid:9760046
pmid:9760077
pmid:9760138
Belumian AA et al. [Ionic mechanisms of action of glycine and gamma-aminobutyric acid on the postsynaptic membrane of amphibian motoneurons]. 1976 Dokl. Akad. Nauk SSSR pmid:976054
pmid:9761298
pmid:9761322
pmid:9761324
pmid:9762870
pmid:9763458
pmid:9763492
pmid:9763621
pmid:9763645
Orr HT et al. The levels of free taurine, glutamate, glycine and gamma-amino butyric acid during the postnatal development of the normal and dystrophic retina of the mouse. 1976 Exp. Eye Res. pmid:976379
Logan WJ Amino acid transport by two glial cell lines and by proliferating glia. 1976 Exp. Neurol. pmid:976410
pmid:9764538
pmid:9764858
Giorgetti M et al. Imidazenil, a positive allosteric GABAA receptor modulator, inhibits the effects of cocaine on locomotor activity and extracellular dopamine in the nucleus accumbens shell without tolerance liability. 1998 J. Pharmacol. Exp. Ther. pmid:9765322
Van Bockstaele EJ Morphological substrates underlying opioid, epinephrine and gamma-aminobutyric acid inhibitory actions in the rat locus coeruleus. 1998 Brain Res. Bull. pmid:9766384
Guthmann A et al. GABA, GABA transporters, GABA(A) receptor subunits, and GAD mRNAs in the rat parabrachial and Kölliker-Fuse nuclei. 1998 J. Comp. Neurol. pmid:9766401
Sorkin LS et al. Spinal bicuculline produces hypersensitivity of dorsal horn neurons: effects of excitatory amino acid antagonists. 1998 Pain pmid:9766836
Goebel DJ et al. Immunocytochemical localization of the NMDA-R2A receptor subunit in the cat retina. 1998 Brain Res. pmid:9767152
Vinay L et al. Spinal inputs from lateral columns to reticulospinal neurons in lampreys. 1998 Brain Res. pmid:9767174
Ballanyi K and Kulik A Intracellular Ca2+ during metabolic activation of KATP channels in spontaneously active dorsal vagal neurons in medullary slices. 1998 Eur. J. Neurosci. pmid:9767388
Tunnicliff G Centrally-acting drugs and the formation of brain gamma-aminobutyric acid. 1976 Gen. Pharmacol. pmid:976740
Avoli M et al. GABA-dependent generation of ectopic action potentials in the rat hippocampus. 1998 Eur. J. Neurosci. pmid:9767401
Santos PF et al. Differential acetylcholine and GABA release from cultured chick retina cells. 1998 Eur. J. Neurosci. pmid:9767402
Rutherford LC et al. BDNF has opposite effects on the quantal amplitude of pyramidal neuron and interneuron excitatory synapses. 1998 Neuron pmid:9768839
Shiah IS and Yatham LN GABA function in mood disorders: an update and critical review. 1998 Life Sci. pmid:9768867
Engel D et al. Laminar difference in GABA uptake and GAT-1 expression in rat CA1. 1998 J. Physiol. (Lond.) pmid:9769410
Mienville JM Persistent depolarizing action of GABA in rat Cajal-Retzius cells. 1998 J. Physiol. (Lond.) pmid:9769423
De Luka SR et al. [Gamma aminobutyric acid--its function, disorders and their sequelae]. 1998 Jul-Aug Med. Pregl. pmid:9769665
Scott RC et al. Status epilepticus: pathophysiology, epidemiology, and outcomes. 1998 Arch. Dis. Child. pmid:9771258
Schwartzkroin PA GABA synapses enter the molecular big time. 1998 Nat. Med. pmid:9771735
Corá-Locatelli G et al. Gabapentin augmentation for fluoxetine-treated patients with obsessive-compulsive disorder. 1998 J Clin Psychiatry pmid:9771822
Fernández A et al. The marginal nuclei of the spinal cord in turtles: neuron assemblies in which gamma-aminobutyric acid and nitric oxide synthase are colocalized. 1998 Exp Brain Res pmid:9772120
Kapur A and Haberly LB Duration of NMDA-dependent synaptic potentiation in piriform cortex in vivo is increased after epileptiform bursting. 1998 J. Neurophysiol. pmid:9772226
Gao F and Wu SM Characterization of spontaneous inhibitory synaptic currents in salamander retinal ganglion cells. 1998 J. Neurophysiol. pmid:9772236
Tate AK and Malpeli JG Effects of focal inactivation of dorsal or ventral layers of the lateral geniculate nucleus on cats' ability to see and fixate small targets. 1998 J. Neurophysiol. pmid:9772272
Ferraro L et al. The effects of modafinil on striatal, pallidal and nigral GABA and glutamate release in the conscious rat: evidence for a preferential inhibition of striato-pallidal GABA transmission. 1998 Neurosci. Lett. pmid:9774168
Murphy SM et al. Pre-embedding staining for GAD67 versus postembedding staining for GABA as markers for central GABAergic terminals. 1998 J. Histochem. Cytochem. pmid:9774625
Garaizar C et al. [Therapeutic failure, treatment and non-treatment of childhood epilepsy]. 1998 Rev Neurol pmid:9774821
Fadda F and Rossetti ZL Chronic ethanol consumption: from neuroadaptation to neurodegeneration. 1998 Prog. Neurobiol. pmid:9775400