4-aminobutyric acid

4-aminobutyric acid is a lipid of Fatty Acyls (FA) class. 4-aminobutyric acid is associated with abnormalities such as Epilepsy and Premenstrual syndrome. The involved functions are known as Binding (Molecular Function), neuron survival, Process, Uptake and physiological aspects. 4-aminobutyric acid often locates in Microglial, Neurofilament, Neuraxis, Brain region and Neurites. The associated genes with 4-aminobutyric acid are arginine methyl ester, SLC33A1 gene, NKS1 gene, P4HTM gene and ITSN2 gene. The related lipids are pregnenolone sulfate, pregnane-20-one, Pregnanes, Steroids and endogenous steroids.

Cross Reference

Introduction

To understand associated biological information of 4-aminobutyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with 4-aminobutyric acid?

4-aminobutyric acid is suspected in Premenstrual syndrome, Epilepsy and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 4-aminobutyric acid

MeSH term MeSH ID Detail
Asphyxia D001237 5 associated lipids
Ascorbic Acid Deficiency D001206 9 associated lipids
Arthritis, Experimental D001169 24 associated lipids
Arthritis D001168 41 associated lipids
Arrhythmias, Cardiac D001145 42 associated lipids
Arachnoiditis D001100 1 associated lipids
Aphakia D001035 1 associated lipids
Amyotrophic Lateral Sclerosis D000690 11 associated lipids
Amnesia, Retrograde D000648 2 associated lipids
Amnesia D000647 12 associated lipids
Renal Aminoacidurias D000608 2 associated lipids
Alzheimer Disease D000544 76 associated lipids
Alcoholism D000437 27 associated lipids
Alcoholic Intoxication D000435 15 associated lipids
Alcohol Amnestic Disorder D000425 2 associated lipids
Adrenoleukodystrophy D000326 29 associated lipids
Adrenal Cortex Diseases D000303 1 associated lipids
Adenoma D000236 40 associated lipids
Adenocarcinoma D000230 166 associated lipids
Acidosis, Lactic D000140 8 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with 4-aminobutyric acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with 4-aminobutyric acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with 4-aminobutyric acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with 4-aminobutyric acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with 4-aminobutyric acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with 4-aminobutyric acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with 4-aminobutyric acid

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Authors Title Published Journal PubMed Link
Meye FJ et al. Morphine withdrawal enhances constitutive μ-opioid receptor activity in the ventral tegmental area. 2012 J. Neurosci. pmid:23152596
Geng Y et al. Triptolide down-regulates COX-2 expression and PGE2 release by suppressing the activity of NF-κB and MAP kinases in lipopolysaccharide-treated PC12 cells. 2012 Phytother Res pmid:21717513
Hazell GG et al. G protein-coupled receptors in the hypothalamic paraventricular and supraoptic nuclei--serpentine gateways to neuroendocrine homeostasis. 2012 Front Neuroendocrinol pmid:21802439
Perego C et al. Neurosteroid allopregnanolone regulates EAAC1-mediated glutamate uptake and triggers actin changes in Schwann cells. 2012 J. Cell. Physiol. pmid:21688266
Lin PP et al. Inhibition of cardiac hypertrophy by probiotic-fermented purple sweet potato yogurt in spontaneously hypertensive rat hearts. 2012 Int. J. Mol. Med. pmid:23064753
Hagerman R et al. Fragile X syndrome and targeted treatment trials. 2012 Results Probl Cell Differ pmid:22009360
Bracamontes JR et al. A neurosteroid potentiation site can be moved among GABAA receptor subunits. 2012 J. Physiol. (Lond.) pmid:22988137
Li WR et al. Pharmacokinetics of natural borneol after oral administration in mice brain and its effect on excitation ratio. 2012 Eur J Drug Metab Pharmacokinet pmid:21948240
Wang M et al. Acute restraint stress enhances hippocampal endocannabinoid function via glucocorticoid receptor activation. 2012 J. Psychopharmacol. (Oxford) pmid:21890595
Garrido P et al. Aging impairs the control of prefrontal cortex on the release of corticosterone in response to stress and on memory consolidation. 2012 Neurobiol. Aging pmid:21794953
Bosch OG et al. Reconsidering GHB: orphan drug or new model antidepressant? 2012 J. Psychopharmacol. (Oxford) pmid:21926421
Lucenteforte E et al. Complementary and Alternative Drugs Use among Preoperative Patients: A Cross-Sectional Study in Italy. 2012 Evid Based Complement Alternat Med pmid:21822441
Lecker I et al. Tranexamic acid concentrations associated with human seizures inhibit glycine receptors. 2012 J. Clin. Invest. pmid:23187124
Al-Wadei HA et al. Social stress promotes and γ-aminobutyric acid inhibits tumor growth in mouse models of non-small cell lung cancer. 2012 Cancer Prev Res (Phila) pmid:21955519
López-López J et al. Inferior alveolar nerve injury resulting from overextension of an endodontic sealer: non-surgical management using the GABA analogue pregabalin. 2012 Int Endod J pmid:21883296
Benjaminsen E et al. A man in his seventies with prolonged myasthenic crisis. 2012 Tidsskr. Nor. Laegeforen. pmid:23076489
Uetake K et al. Calming effect of orally administered γ-aminobutyric acid in Shih Tzu dogs. 2012 Anim. Sci. J. pmid:23216545
Duszczyk-Budhathoki M et al. Administration of thimerosal to infant rats increases overflow of glutamate and aspartate in the prefrontal cortex: protective role of dehydroepiandrosterone sulfate. 2012 Neurochem. Res. pmid:22015977
Maschio M et al. Effect of pregabalin add-on treatment on seizure control, quality of life, and anxiety in patients with brain tumour-related epilepsy: a pilot study. 2012 Epileptic Disord pmid:23248037
Rossi S et al. Interleukin-1β causes anxiety by interacting with the endocannabinoid system. 2012 J. Neurosci. pmid:23035099