| MeSH term | MeSH ID | Detail |
|---|---|---|
| Insulin Resistance | D007333 | 99 associated lipids |
| Brain Ischemia | D002545 | 89 associated lipids |
| Seizures | D012640 | 87 associated lipids |
| Diabetes Mellitus, Experimental | D003921 | 85 associated lipids |
| Pancreatic Neoplasms | D010190 | 77 associated lipids |
| Alzheimer Disease | D000544 | 76 associated lipids |
| Stomach Ulcer | D013276 | 75 associated lipids |
| Hyperlipidemias | D006949 | 73 associated lipids |
| Coronary Disease | D003327 | 70 associated lipids |
| Reperfusion Injury | D015427 | 65 associated lipids |
4-aminobutyric acid
4-aminobutyric acid is a lipid of Fatty Acyls (FA) class. 4-aminobutyric acid is associated with abnormalities such as Epilepsy and Premenstrual syndrome. The involved functions are known as Binding (Molecular Function), neuron survival, Process, Uptake and physiological aspects. 4-aminobutyric acid often locates in Microglial, Neurofilament, Neuraxis, Brain region and Neurites. The associated genes with 4-aminobutyric acid are arginine methyl ester, SLC33A1 gene, NKS1 gene, P4HTM gene and ITSN2 gene. The related lipids are pregnenolone sulfate, pregnane-20-one, Pregnanes, Steroids and endogenous steroids.
Cross Reference
Introduction
To understand associated biological information of 4-aminobutyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with 4-aminobutyric acid?
4-aminobutyric acid is suspected in Premenstrual syndrome, Epilepsy and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with 4-aminobutyric acid
PubChem Associated disorders and diseases
What pathways are associated with 4-aminobutyric acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with 4-aminobutyric acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with 4-aminobutyric acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with 4-aminobutyric acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with 4-aminobutyric acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with 4-aminobutyric acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with 4-aminobutyric acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Perrais D and Ropert N | Effect of zolpidem on miniature IPSCs and occupancy of postsynaptic GABAA receptors in central synapses. | 1999 | J. Neurosci. | pmid:9880578 |
| Jin Y et al. | The Caenorhabditis elegans gene unc-25 encodes glutamic acid decarboxylase and is required for synaptic transmission but not synaptic development. | 1999 | J. Neurosci. | pmid:9880574 |
| Glitsch M and Marty A | Presynaptic effects of NMDA in cerebellar Purkinje cells and interneurons. | 1999 | J. Neurosci. | pmid:9880571 |
| Feely M | Fortnightly review: drug treatment of epilepsy. | 1999 | BMJ | pmid:9880286 |
| Yan XX and Ribak CE | Alteration of GABA transporter expression in the rat cerebral cortex following needle puncture and colchicine injection. | 1999 | Brain Res. | pmid:9878808 |
| Ikarashi Y et al. | Modulation of acetylcholine release via GABAA and GABAB receptors in rat striatum. | 1999 | Brain Res. | pmid:9878759 |
| Commons KG et al. | In the ventromedial nucleus of the rat hypothalamus, GABA-immunolabeled neurons are abundant and are innervated by both enkephalin- and GABA-immunolabeled axon terminals. | 1999 | Brain Res. | pmid:9878688 |
| Serrao M et al. | A case of myokymia-cramp syndrome successfully treated with gabapentin. | 1998 | Acta Neurol. Scand. | pmid:9875627 |
| Brockhaus J and Ballanyi K | Synaptic inhibition in the isolated respiratory network of neonatal rats. | 1998 | Eur. J. Neurosci. | pmid:9875360 |
| Cattaert D and Le Ray D | Direct glutamate-mediated presynaptic inhibition of sensory afferents by the postsynaptic motor neurons. | 1998 | Eur. J. Neurosci. | pmid:9875352 |
| Gonzalez LE et al. | Stimulation of benzodiazepine receptors in the dorsal hippocampus and median raphé reveals differential GABAergic control in two animal tests of anxiety. | 1998 | Eur. J. Neurosci. | pmid:9875346 |
| Pernberg J et al. | Structure and dynamics of receptive fields in the visual cortex of the cat (area 18) and the influence of GABAergic inhibition. | 1998 | Eur. J. Neurosci. | pmid:9875339 |
| Wickelgren I | Drug may suppress the craving for nicotine. | 1998 | Science | pmid:9874627 |
| Czupryn A et al. | Neurotransmitter system markers in adult barrel field. | 1998 | Somatosens Mot Res | pmid:9874522 |
| Kogo M et al. | Examination of the relationships between jaw opener and closer rhythmical muscle activity in an in vitro brainstem jaw-attached preparation. | 1998 | Somatosens Mot Res | pmid:9874519 |
| Bonanno G et al. | GABA(B) receptors as potential targets for drugs able to prevent excessive excitatory amino acid transmission in the spinal cord. | 1998 | Eur. J. Pharmacol. | pmid:9874164 |
| McGraw T and Stacey BR | Gabapentin for treatment of neuropathic pain in a 12-year-old girl. | 1998 | Clin J Pain | pmid:9874016 |
| Carruthers NI et al. | Synthesis of a series of sulfinic acid analogs of GABA and evaluation of their GABAB receptor affinities. | 1998 | Bioorg. Med. Chem. Lett. | pmid:9873676 |
| Serfass L and Casara PJ | General synthesis of 3-substituted alkenyl GABA as potential anticonvulsants. | 1998 | Bioorg. Med. Chem. Lett. | pmid:9873588 |
| Bernstein EM and Quick MW | Regulation of gamma-aminobutyric acid (GABA) transporters by extracellular GABA. | 1999 | J. Biol. Chem. | pmid:9873028 |
| Osborne JP et al. | Infantile spasms and vigabatrin. Study will compare effects of drugs. | 1999 | BMJ | pmid:9872899 |
| Hakkinen HM and Kulonen E | Ethanol intoxication and gamma-aminobutyric acid. | 1976 | J. Neurochem. | pmid:987162 |
| Lima L et al. | Taurine, glutamate and GABA modulate the outgrowth from goldfish retinal explants and its concentrations are affected by the crush of the optic nerve. | 1998 | Amino Acids | pmid:9871499 |
| Ruotsalainen M et al. | Locally infused taurine, GABA and homotaurine alter differently the striatal extracellular concentrations of dopamine and its metabolites in rats. | 1998 | Amino Acids | pmid:9871492 |
| Arias P et al. | Changes in mediobasal hypothalamic dopamine and GABA release: a possible mechanism underlying taurine-induced prolactin secretion. | 1998 | Amino Acids | pmid:9871483 |
| Soghomonian JJ and Martin DL | Two isoforms of glutamate decarboxylase: why? | 1998 | Trends Pharmacol. Sci. | pmid:9871412 |
| Fabian-Fine R et al. | Peripheral synapses at identified mechanosensory neurons in spiders: three-dimensional reconstruction and GABA immunocytochemistry. | 1999 | J. Neurosci. | pmid:9870959 |
| Zhang W et al. | Citron binds to PSD-95 at glutamatergic synapses on inhibitory neurons in the hippocampus. | 1999 | J. Neurosci. | pmid:9870942 |
| de Oliveira JO et al. | Comments on Gould, PAIN, 74 (1998) 341-343. | 1998 | Pain | pmid:9870579 |
| Rada P et al. | In vivo monitoring of gabapentin in rats: a microdialysis study coupled to capillary electrophoresis and laser-induced fluorescence detection. | 1998 | Electrophoresis | pmid:9870398 |
| Dudel J and Hatt H | Four types of GABA receptors in crayfish leg muscles characterized by desensitization and specific antagonist. | 1976 | Pflugers Arch. | pmid:986633 |
| Frye MA et al. | Gabapentin does not alter single-dose lithium pharmacokinetics. | 1998 | J Clin Psychopharmacol | pmid:9864078 |
| O'Connor WT | Functional neuroanatomy of the basal ganglia as studied by dual-probe microdialysis. | 1998 | Nucl. Med. Biol. | pmid:9863560 |
| Zhou HY et al. | [Effects of L-malate, an inhibitor of glutamate decarboxylase, on learning and memory in mice]. | 1996 | Yao Xue Xue Bao | pmid:9863221 |
| Zhang DQ and Yang XL | [The selective suppression of GABA on cone-driven horizontal cells in carp retina]. | 1997 | Sheng Li Xue Bao | pmid:9863185 |
| Xu XG et al. | Exacerbation of cold restraint-induced gastric ulcer by GABA in mice. | 1996 | Zhongguo Yao Li Xue Bao | pmid:9863175 |
| Hua SY et al. | Different VAMP/synaptobrevin complexes for spontaneous and evoked transmitter release at the crayfish neuromuscular junction. | 1998 | J. Neurophysiol. | pmid:9862918 |
| Berman NJ and Maler L | Inhibition evoked from primary afferents in the electrosensory lateral line lobe of the weakly electric fish (Apteronotus leptorhynchus). | 1998 | J. Neurophysiol. | pmid:9862915 |
| Harris JA and Westbrook RF | Evidence that GABA transmission mediates context-specific extinction of learned fear. | 1998 | Psychopharmacology (Berl.) | pmid:9862409 |
| Zhang J and Mifflin SW | Receptor subtype specific effects of GABA agonists on neurons receiving aortic depressor nerve inputs within the nucleus of the solitary tract. | 1998 | J. Auton. Nerv. Syst. | pmid:9862393 |
| Davies J | Effects of morphine and naloxone on Renshaw cells and spinal interneurones in morphine dependent and non-dependent rats. | 1976 | Brain Res. | pmid:986228 |
| Iwasa K et al. | Gamma aminobutyric acid immunoreactivity in the mouse adrenal gland during postnatal development. | 1998 | Arch. Histol. Cytol. | pmid:9862152 |
| Pyza E and Meinertzhagen IA | Neurotransmitters alter the numbers of synapses and organelles in photoreceptor terminals in the lamina of the housefly, Musca domestica. | 1998 | J. Comp. Physiol. A | pmid:9861706 |
| Jen PH et al. | Corticofugal regulation of auditory sensitivity in the bat inferior colliculus. | 1998 | J. Comp. Physiol. A | pmid:9861704 |
| Serretti A et al. | GABAA alpha-1 subunit gene not associated with depressive symptomatology in mood disorders. | 1998 | Psychiatr. Genet. | pmid:9861645 |
| Malick JB and Goldstein JM | Gamma-aminobutyric acid: selective inhibition of electrically induced head-turning following intracaudate administration. | 1976 | Arch Int Pharmacodyn Ther | pmid:986127 |
| Sagatelian AK et al. | [GABA-Activated cloride currents in isolated spinal neurons from lamprey, Lampetra fluviatilis]. | 1998 Jul-Aug | Zh. Evol. Biokhim. Fiziol. | pmid:9859181 |
| Arroyo S et al. | [Drug-resistant epilepsy]. | 1998 | Rev Neurol | pmid:9859169 |
| Santos PF et al. | [3H]acetylcholine release from rat amacrine-like neurons is inhibited by adenosine A1 receptor activation. | 1998 | Neuroreport | pmid:9858381 |
| Lewis DA | Chandelier cells: shedding light on altered cortical circuitry in schizophrenia. | 1998 | Mol. Psychiatry | pmid:9857967 |