4-aminobutyric acid is a lipid of Fatty Acyls (FA) class. 4-aminobutyric acid is associated with abnormalities such as Epilepsy and Premenstrual syndrome. The involved functions are known as Binding (Molecular Function), neuron survival, Process, Uptake and physiological aspects. 4-aminobutyric acid often locates in Microglial, Neurofilament, Neuraxis, Brain region and Neurites. The associated genes with 4-aminobutyric acid are arginine methyl ester, SLC33A1 gene, NKS1 gene, P4HTM gene and ITSN2 gene. The related lipids are pregnenolone sulfate, pregnane-20-one, Pregnanes, Steroids and endogenous steroids.
To understand associated biological information of 4-aminobutyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
4-aminobutyric acid is suspected in Premenstrual syndrome, Epilepsy and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with 4-aminobutyric acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Chou HT et al. | Functional characterization of the agtABCD and agtSR operons for 4-aminobutyrate and 5-aminovalerate uptake and regulation in Pseudomonas aeruginosa PAO1. | 2014 | Curr. Microbiol. | pmid:23982201 |
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Valdeolivas S et al. | The inhibition of 2-arachidonoyl-glycerol (2-AG) biosynthesis, rather than enhancing striatal damage, protects striatal neurons from malonate-induced death: a potential role of cyclooxygenase-2-dependent metabolism of 2-AG. | 2013 | Cell Death Dis | pmid:24136226 |
Owada K | [Therapeuetic aspects of cluster headache in the practical clinical site]. | 2013 | Rinsho Shinkeigaku | pmid:24291904 |
Liu J et al. | Pharmacological treatment for pain in Guillain-Barré syndrome. | 2013 | Cochrane Database Syst Rev | pmid:24142399 |
Kostić N et al. | Effects of derivatization reagents consisting of n-alkyl chloroformate/n-alcohol combinations in LC-ESI-MS/MS analysis of zwitterionic antiepileptic drugs. | 2013 | Talanta | pmid:24148378 |
Gialanella B et al. | Low back pain radiating to the leg: an atypical cause. | 2013 | Clin Ter | pmid:24217828 |
Muhammad SI et al. | Upregulation of genes related to bone formation by γ-amino butyric acid and γ-oryzanol in germinated brown rice is via the activation of GABAB-receptors and reduction of serum IL-6 in rats. | 2013 | Clin Interv Aging | pmid:24098073 |
Owusu-Ware SK et al. | Novel analytical approaches for the study of mobility and relaxation phenomena in positional isomers of GABA. | 2013 | Phys Chem Chem Phys | pmid:24154789 |
Thangamani D et al. | The anticonvulsant enaminone E139 attenuates paclitaxel-induced neuropathic pain in rodents. | 2013 | ScientificWorldJournal | pmid:24385872 |