4-aminobutyric acid is a lipid of Fatty Acyls (FA) class. 4-aminobutyric acid is associated with abnormalities such as Epilepsy and Premenstrual syndrome. The involved functions are known as Binding (Molecular Function), neuron survival, Process, Uptake and physiological aspects. 4-aminobutyric acid often locates in Microglial, Neurofilament, Neuraxis, Brain region and Neurites. The associated genes with 4-aminobutyric acid are arginine methyl ester, SLC33A1 gene, NKS1 gene, P4HTM gene and ITSN2 gene. The related lipids are pregnenolone sulfate, pregnane-20-one, Pregnanes, Steroids and endogenous steroids.
To understand associated biological information of 4-aminobutyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
4-aminobutyric acid is suspected in Premenstrual syndrome, Epilepsy and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with 4-aminobutyric acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Tasker JG et al. | Local glutamatergic and GABAergic synaptic circuits and metabotropic glutamate receptors in the hypothalamic paraventricular and supraoptic nuclei. | 1998 | Adv. Exp. Med. Biol. | pmid:10026791 |
Thomas A and Amico JA | Progesterone regulates hypothalamic oxytocin mRNA levels through gamma aminobutyric acid. | 1998 | Adv. Exp. Med. Biol. | pmid:10026792 |
Wilke RA et al. | Membrane excitability in the neurohypophysis. | 1998 | Adv. Exp. Med. Biol. | pmid:10026805 |
Abe M and Matsuda M | A correlation between changes in gamma-aminobutyric acid metabolism and seizures induced by antivitamin B6. | 1976 | J. Biochem. | pmid:1002683 |
Pan HL et al. | Gabapentin suppresses ectopic nerve discharges and reverses allodynia in neuropathic rats. | 1999 | J. Pharmacol. Exp. Ther. | pmid:10027839 |
Nomura M et al. | Novel characteristic for distinguishing Lactococcus lactis subsp. lactis from subsp. cremoris. | 1999 | Int. J. Syst. Bacteriol. | pmid:10028257 |
Rocha ES et al. | An analysis of low level doses of cholinesterase inhibitors in cultured neurons and hippocampal slices of rats. | 1998 | Drug Chem Toxicol | pmid:10028411 |
Patte C et al. | GABA inhibits endozepine release from cultured rat astrocytes. | 1999 | Glia | pmid:10028922 |
Bird M and Owen A | Neurite outgrowth-regulating properties of GABA and the effect of serum on mouse spinal cord neurons in culture. | 1998 | J. Anat. | pmid:10029183 |
Renno WM et al. | Quantitative immunoelectron microscopic colocalization of GABA and enkephalin in the ventrocaudal periaqueductal gray of the rat. | 1999 | Synapse | pmid:10029240 |