4-aminobutyric acid
4-aminobutyric acid is a lipid of Fatty Acyls (FA) class. 4-aminobutyric acid is associated with abnormalities such as Epilepsy and Premenstrual syndrome. The involved functions are known as Binding (Molecular Function), neuron survival, Process, Uptake and physiological aspects. 4-aminobutyric acid often locates in Microglial, Neurofilament, Neuraxis, Brain region and Neurites. The associated genes with 4-aminobutyric acid are arginine methyl ester, SLC33A1 gene, NKS1 gene, P4HTM gene and ITSN2 gene. The related lipids are pregnenolone sulfate, pregnane-20-one, Pregnanes, Steroids and endogenous steroids.
Cross Reference
Introduction
To understand associated biological information of 4-aminobutyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with 4-aminobutyric acid?
4-aminobutyric acid is suspected in Premenstrual syndrome, Epilepsy and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with 4-aminobutyric acid
PubChem Associated disorders and diseases
What pathways are associated with 4-aminobutyric acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with 4-aminobutyric acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with 4-aminobutyric acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with 4-aminobutyric acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with 4-aminobutyric acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with 4-aminobutyric acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with 4-aminobutyric acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Ylinen A | Antiepileptic efficacy of vigabatrin in people with severe epilepsy and intellectual disability. | 1998 | J Intellect Disabil Res | pmid:10030432 |
| Mikati MA et al. | Gabapentin in the treatment of refractory partial epilepsy in children with intellectual disability. | 1998 | J Intellect Disabil Res | pmid:10030434 |
| Corrigall WA et al. | Electrophysiological studies of fetal mouse olifactory bulb explants during development of synaptic functions in culture. | 1976 | J. Neurobiol. | pmid:1003199 |
| Perry TL and Hansen S | Is GABA detectable in human CSF? | 1976 | J. Neurochem. | pmid:1003229 |
| Lodge D et al. | The uptake of GABA and beta-alanine in slices of cat and rat CNS tissue: regional differences in susceptibility to inhibitors. | 1976 | J. Neurochem. | pmid:1003233 |
| Lake N and Voaden MJ | Exchange versus net uptake of exogenously-applied gamma-aminobutyric acid in retina. | 1976 | J. Neurochem. | pmid:1003234 |
| Dumoulin A et al. | Presence of the vesicular inhibitory amino acid transporter in GABAergic and glycinergic synaptic terminal boutons. | 1999 | J. Cell. Sci. | pmid:10036231 |
| Tredway TL et al. | N-type voltage-dependent calcium channels mediate the nicotinic enhancement of GABA release in chick brain. | 1999 | J. Neurophysiol. | pmid:10036250 |
| Hirose N et al. | Effects of propofol and fentanyl on extracellular levels of gamma-aminobutyric acid in the rat nucleus accumbens: an in vivo microdialysis study. | 1998 | J Oral Sci | pmid:10036830 |
| Sellstrom A et al. | Functional assessment of GABA uptake or exchange by synaptosomal fractions. | 1976 | Nature | pmid:1004608 |
| Göthert M et al. | Inhibition of catecholamine release from the adrenal medulla by halothane. Site and mechanism of action. | 1976 | Naunyn Schmiedebergs Arch. Pharmacol. | pmid:1004635 |
| Zsilla G et al. | Regional changes in the rate of turnover of acetylcholine in rat brain following diazepam or muscimol. | 1976 | Naunyn Schmiedebergs Arch. Pharmacol. | pmid:1004636 |
| Thomas A et al. | The effects of progesterone on oxytocin mRNA levels in the paraventricular nucleus of the female rat can be altered by the administration of diazepam or RU486. | 1999 | J. Neuroendocrinol. | pmid:10048469 |
| Hirota K et al. | GABAergic mechanisms in the action of general anesthetics. | 1998 | Toxicol. Lett. | pmid:10049143 |
| Ikemoto Y et al. | Volatile anesthetics and a volatile convulsant differentially affect GABA(A) receptor-chloride channel complex. | 1998 | Toxicol. Lett. | pmid:10049146 |
| Thompson SA et al. | Functional characteristics of recombinant human GABA(A) receptors containing the epsilon-subunit. | 1998 | Toxicol. Lett. | pmid:10049148 |
| Crump FT et al. | Localization of the brain-specific high-affinity l-proline transporter in cultured hippocampal neurons: molecular heterogeneity of synaptic terminals. | 1999 | Mol. Cell. Neurosci. | pmid:10049529 |
| DeToledo JC et al. | Skin eruption with gabapentin in a patient with repeated AED-induced Stevens-Johnson's syndrome. | 1999 | Ther Drug Monit | pmid:10051068 |
| Zeng XJ and Tietz EI | Benzodiazepine tolerance at GABAergic synapses on hippocampal CA1 pyramidal cells. | 1999 | Synapse | pmid:10051107 |
| Katona I et al. | Postsynaptic targets of somatostatin-immunoreactive interneurons in the rat hippocampus. | 1999 | Neuroscience | pmid:10051188 |