4-aminobutyric acid is a lipid of Fatty Acyls (FA) class. 4-aminobutyric acid is associated with abnormalities such as Epilepsy and Premenstrual syndrome. The involved functions are known as Binding (Molecular Function), neuron survival, Process, Uptake and physiological aspects. 4-aminobutyric acid often locates in Microglial, Neurofilament, Neuraxis, Brain region and Neurites. The associated genes with 4-aminobutyric acid are arginine methyl ester, SLC33A1 gene, NKS1 gene, P4HTM gene and ITSN2 gene. The related lipids are pregnenolone sulfate, pregnane-20-one, Pregnanes, Steroids and endogenous steroids.
To understand associated biological information of 4-aminobutyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
4-aminobutyric acid is suspected in Premenstrual syndrome, Epilepsy and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with 4-aminobutyric acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Holt RA et al. | Decreased GABA enhancement of benzodiazepine binding after a single dose of diazepam. | 1999 | J. Neurochem. | pmid:10217306 |
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Burrows KB and Meshul CK | High-dose methamphetamine treatment alters presynaptic GABA and glutamate immunoreactivity. | 1999 | Neuroscience | pmid:10218784 |
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Shen W et al. | Pregnenolone sulfate and dehydroepiandrosterone sulfate inhibit GABA-gated chloride currents in Xenopus oocytes expressing picrotoxin-insensitive GABA(A) receptors. | 1999 | Neuropharmacology | pmid:10218867 |
Melnick IV et al. | Rat hippocampal neurons maintain their own GABAergic synaptic transmission in culture. | 1999 | Neurosci. Lett. | pmid:10218878 |
Kaehler ST et al. | Hyperforin enhances the extracellular concentrations of catecholamines, serotonin and glutamate in the rat locus coeruleus. | 1999 | Neurosci. Lett. | pmid:10218890 |
Novotny EJ et al. | GABA changes with vigabatrin in the developing human brain. | 1999 | Epilepsia | pmid:10219272 |
Boyd RA et al. | Effects of age and gender on single-dose pharmacokinetics of gabapentin. | 1999 | Epilepsia | pmid:10219274 |
Pollák E and Molnár L | Distribution of GABA-immunoreactive neurons in the terminal ganglion of the isopod Porcellio scaber. | 1998 | Neurobiology (Bp) | pmid:10220781 |
Jelitai M et al. | Non-synaptic effects of glutamic acid and GABA in cultures of developing neural cells. | 1998 | Neurobiology (Bp) | pmid:10220788 |
Cabras PL et al. | Clinical experience with gabapentin in patients with bipolar or schizoaffective disorder: results of an open-label study. | 1999 | J Clin Psychiatry | pmid:10221286 |
Dahl-Jørgensen A et al. | Serum and CNTF stimulate oligodendroglia and reduce fiber outgrowth from striatal cultures. | 1999 | Exp. Neurol. | pmid:10222111 |
Schlösser B et al. | Local disinhibition of neocortical neuronal circuits causes augmentation of glutamatergic and GABAergic synaptic transmission in the rat neostriatum in vitro. | 1999 | Exp. Neurol. | pmid:10222121 |
Petroff OA et al. | Effects of valproate and other antiepileptic drugs on brain glutamate, glutamine, and GABA in patients with refractory complex partial seizures. | 1999 | Seizure | pmid:10222306 |